{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:26:30Z","timestamp":1793759190908,"version":"4.6.1"},"reference-count":13,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["dom-pubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Obesity Metabolism"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Accurate continuous glucose monitoring (CGM) is essential for diabetes management. This study evaluated the accuracy and safety of the LinX CGM system over 15\u2009days in adults with diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective, multicentre, open\u2010label clinical performance study, 87 adults who wore two LinX sensors were enrolled. Reference glucose was measured using a Biosen analyser. Primary endpoints were the proportions of readings within \u00b115%\/\u00b140% of reference values and mean absolute relative difference (MARD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall\n                      <jats:styled-content style=\"fixed-case\">MARD<\/jats:styled-content>\n                      was 8.66% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 8.27%\u20139.05%). For glucose concentrations in the range of 3.9\u201310.0\u2009mmol\/L (70\u2013180\u2009mg\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      ), 87.2% of readings were within \u00b115%; for concentrations \u2265\u200910.0\u2009mmol\/L (\u2265\u2009180\u2009mg\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      ), 90.2% were within \u00b115%. Within \u00b140%, agreement rates were 99.8% and 100.0%, respectively. Sensor survival at 15\u2009days was 96.0%. No serious adverse events occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The LinX CGM system demonstrated good analytical accuracy and favourable short\u2010term safety over a 15\u2010day wear period in adults with diabetes.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      Chinese Clinical Trial Registry: ChiCTR2200064004\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dom.71392","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:12:16Z","timestamp":1790903536000},"page":"11927-11935","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Accuracy and Safety of the\n                    <scp>LinX<\/scp>\n                    Continuous Glucose Monitoring System in Adults With Diabetes: A Prospective Multicentre Open\u2010Label Clinical Performance Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4537-8969","authenticated-orcid":false,"given":"Yang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Endocrinology The Eighth Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The First Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yimei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The Eighth Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The Eighth Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingguang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The Seventh Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Beijing Pinggu Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Microtech Medical Device (Hangzhou) Co. Ltd.  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The Eighth Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3344-3540","authenticated-orcid":false,"given":"Yiming","family":"Mu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology The First Medical Center of PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci18-0002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2017.3"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.19975"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc23-2194"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.19976"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci23-0036"},{"key":"e_1_2_11_8_1","first-page":"537","article-title":"Continuous Glucose Monitoring in Type 1 Diabetes, Type 2 Diabetes, and Diabetes During Pregnancy: A Systematic Review With Meta\u2010Analysis of Randomized Controlled Trials","volume":"7","author":"Rizos E. C.","year":"2025","journal-title":"Diabetes Technology & Therapeutics"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25-S007"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2022.0011"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/19322968251329364"},{"key":"e_1_2_11_12_1","unstructured":"Center for Medical Device Evaluation National Medical Products Administration \u201cGuidelines for the Technical Review of Registration for Continuous Glucose Monitoring Systems \u201d2023 https:\/\/www.cnpharm.com\/upload\/resources\/file\/2023\/07\/18\/141594.pdf."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2019.0014"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1932296817706377"}],"container-title":["Diabetes, Obesity and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dom.71392","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dom.71392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:02:53Z","timestamp":1793757773000},"score":1,"resource":{"primary":{"URL":"https:\/\/dom-pubs.onlinelibrary.wiley.com\/doi\/10.1111\/dom.71392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":13,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["10.1111\/dom.71392"],"URL":"https:\/\/doi.org\/10.1111\/dom.71392","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/DOM.71392\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/review5","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/DOM.71392\/v1\/review1","asserted-by":"object"}]},"ISSN":["1462-8902","1463-1326"],"issn-type":[{"value":"1462-8902","type":"print"},{"value":"1463-1326","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"assertion":[{"value":"2026-05-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}