{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T15:05:17Z","timestamp":1770563117088,"version":"3.49.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases of the Esophagus"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1111\/dote.12491","type":"journal-article","created":{"date-parts":[[2016,6,25]],"date-time":"2016-06-25T16:23:10Z","timestamp":1466871790000},"source":"Crossref","is-referenced-by-count":24,"title":["Complications of botulinum toxin injections for treatment of esophageal motility disorders\u2020"],"prefix":"10.1093","author":[{"given":"Froukje B.","family":"van Hoeij","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology; Academic Medical Center, University of Amsterdam; Amsterdam Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan F.","family":"Tack","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology; University Hospital Gasthuisberg, University of Leuven; Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E.","family":"Pandolfino","sequence":"additional","affiliation":[{"name":"Department of Medicine; Northwestern Memorial Hospital, Northwestern University; Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel M.","family":"Sternbach","sequence":"additional","affiliation":[{"name":"Department of Medicine; Northwestern Memorial Hospital, Northwestern University; Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Roman","sequence":"additional","affiliation":[{"name":"Department of Physiology; Hospices Civils de Lyon, Lyon 1 University; Lyon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 J. P. M.","family":"Smout","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology; Academic Medical Center, University of Amsterdam; Amsterdam Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert J.","family":"Bredenoord","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology; Academic Medical Center, University of Amsterdam; Amsterdam Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2016,6,24]]},"reference":[{"issue":"9","key":"10.1111\/dote.12491-BIB0001|dote12491-cit-0001","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.cgh.2013.03.021","article-title":"Botulinum toxin reduces Dysphagia in patients with nonachalasia primary esophageal motility disorders","volume":"11","author":"Vanuytsel","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"5","key":"10.1111\/dote.12491-BIB0002|dote12491-cit-0002","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1053\/gast.1996.v110.pm8613045","article-title":"Botulinum toxin for achalasia: long-term outcome and predictors of response","volume":"110","author":"Pasricha","year":"1996","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1111\/dote.12491-BIB0003|dote12491-cit-0003","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1038\/ajg.2012.332","article-title":"Major complications of pneumatic dilation and Heller myotomy for achalasia: single-center experience and systematic review of the literature","volume":"107","author":"Lynch","year":"2012","journal-title":"Am J Gastroenterol"},{"issue":"12","key":"10.1111\/dote.12491-BIB0004|dote12491-cit-0004","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1055\/s-2001-18935","article-title":"Treatment of achalasia: botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-up","volume":"33","author":"Allescher","year":"2001","journal-title":"Endoscopy"},{"issue":"1","key":"10.1111\/dote.12491-BIB0005|dote12491-cit-0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2036.2003.01598.x","article-title":"Review article: botulinum toxin in the therapy of gastrointestinal motility disorders","volume":"18","author":"Gui","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/dote.12491-BIB0006|dote12491-cit-0006","first-page":"Cd005046","article-title":"Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia","volume":"12","author":"Leyden","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl. 2","key":"10.1111\/dote.12491-BIB0007|dote12491-cit-0007","article-title":"Fatal mediastinitis following botulinum toxin injection for esophageal spasm","volume":"45","author":"Marjoux","year":"2013","journal-title":"Endoscopy"},{"issue":"8839","key":"10.1111\/dote.12491-BIB0008|dote12491-cit-0008","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/0140-6736(93)90109-T","article-title":"Botulinum toxin for achalasia","volume":"341","author":"Pasricha","year":"1993","journal-title":"Lancet"},{"issue":"17","key":"10.1111\/dote.12491-BIB0009|dote12491-cit-0009","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1056\/NEJM199104253241707","article-title":"Therapeutic uses of botulinum toxin","volume":"324","author":"Jankovic","year":"1991","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1111\/dote.12491-BIB0010|dote12491-cit-0010","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1067\/mge.2001.119256","article-title":"Treatment of symptomatic diffuse esophageal spasm by endoscopic injections of botulinum toxin: a prospective study with long-term follow-up","volume":"54","author":"Storr","year":"2001","journal-title":"Gastrointest Endosc"},{"issue":"5","key":"10.1111\/dote.12491-BIB0011|dote12491-cit-0011","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1136\/gut.46.5.597","article-title":"A multicentre randomised study of intrasphincteric botulinum toxin in patients with oesophageal achalasia. GISMAD Achalasia Study Group","volume":"46","author":"Annese","year":"2000","journal-title":"Gut"},{"issue":"1","key":"10.1111\/dote.12491-BIB0012|dote12491-cit-0012","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/gut.41.1.87","article-title":"Achalasia: outcome of patients treated with intrasphincteric injection of botulinum toxin","volume":"41","author":"Cuilliere","year":"1997","journal-title":"Gut"},{"issue":"7","key":"10.1111\/dote.12491-BIB0013|dote12491-cit-0013","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1185\/030079904125003962","article-title":"Safety of botulinum toxin type A: a systematic review and meta-analysis","volume":"20","author":"Naumann","year":"2004","journal-title":"Curr Med Res Opin"},{"issue":"3","key":"10.1111\/dote.12491-BIB0014|dote12491-cit-0014","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/01.sla.0000114217.52941.c5","article-title":"Randomized controlled trial of botulinum toxin versus laparoscopic heller myotomy for esophageal achalasia","volume":"239","author":"Zaninotto","year":"2004","journal-title":"Ann Surgery"},{"issue":"5","key":"10.1111\/dote.12491-BIB0015|dote12491-cit-0015","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1097\/01.meg.0000059132.68845.be","article-title":"Pneumothorax complicating botulinum toxin injection in the body of a dilated oesophagus in achalasia","volume":"15","author":"Weusten","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"3","key":"10.1111\/dote.12491-BIB0016|dote12491-cit-0016","doi-asserted-by":"crossref","first-page":"290 e5","DOI":"10.1016\/j.ajem.2013.10.017","article-title":"A new facial expression to botox!","volume":"32","author":"Aggarwal","year":"2014","journal-title":"Am J Emerg Med"},{"issue":"11","key":"10.1111\/dote.12491-BIB0017|dote12491-cit-0017","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1111\/j.1572-0241.2001.05290.x","article-title":"Urinary retention secondary to detrusor muscle hypofunction after botulinum toxin injection for achalasia","volume":"96","author":"Khurana","year":"2001","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1111\/dote.12491-BIB0018|dote12491-cit-0018","doi-asserted-by":"crossref","first-page":"38,","DOI":"10.1097\/00005176-200207000-00009","article-title":"Clinical quiz. Sinus tract between esophagus and fundus","volume":"35","author":"Fitzgerald","year":"2002","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"7","key":"10.1111\/dote.12491-BIB0019|dote12491-cit-0019","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.gie.2009.10.034","article-title":"Acute reversible gastroparesis and megaduodenum after botulinum toxin injection for achalasia","volume":"71","author":"Radaelli","year":"2010","journal-title":"Gastrointest Endosc"},{"issue":"2","key":"10.1111\/dote.12491-BIB0020|dote12491-cit-0020","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1097\/00004836-199809000-00017","article-title":"Symptomatic gastroparesis in a patient with achalasia","volume":"27","author":"Gutierrez-Galiana","year":"1998","journal-title":"J Clin Gastroenterol"},{"issue":"4","key":"10.1111\/dote.12491-BIB0021|dote12491-cit-0021","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1023\/A:1018843526027","article-title":"Untoward effects of esophageal botulinum toxin injection in the treatment of achalasia","volume":"42","author":"Eaker","year":"1997","journal-title":"Dig Dis Sci"},{"issue":"10","key":"10.1111\/dote.12491-BIB0022|dote12491-cit-0022","first-page":"1812","article-title":"Prospective study of esophageal botulinum toxin injection in high-risk achalasia patients","volume":"92","author":"Gordon","year":"1997","journal-title":"Am J Gastroenterol"},{"issue":"5","key":"10.1111\/dote.12491-BIB0023|dote12491-cit-0023","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/den.12392","article-title":"Esophageal perforation, inflammatory mediastinitis and pseudoaneurysm of the thoracic aorta as potential complications of botulinum toxin injection for achalasia","volume":"27","author":"Chao","year":"2014","journal-title":"Dig Endosc"},{"issue":"10","key":"10.1111\/dote.12491-BIB0024|dote12491-cit-0024","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/ncpgasthep0951","article-title":"A case of mediastinitis following botulinum toxin type A treatment for achalasia","volume":"4","author":"Mac Iver","year":"2007","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"issue":"11","key":"10.1111\/dote.12491-BIB0025|dote12491-cit-0025","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1111\/j.1572-0241.2000.03331.x","article-title":"Fatal heart block following treatment with botulinum toxin for achalasia","volume":"95","author":"Malnick","year":"2000","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"10.1111\/dote.12491-BIB0026|dote12491-cit-0026","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surgery"},{"issue":"12","key":"10.1111\/dote.12491-BIB0027|dote12491-cit-0027","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1056\/NEJM199503233321203","article-title":"Intrasphincteric botulinum toxin for the treatment of achalasia","volume":"332","author":"Pasricha","year":"1995","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1111\/dote.12491-BIB0028|dote12491-cit-0028","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1023\/A:1026660921776","article-title":"Effects of previous treatment on results of laparoscopic Heller myotomy for achalasia","volume":"44","author":"Patti","year":"1999","journal-title":"Dig Dis Sci"},{"issue":"9","key":"10.1111\/dote.12491-BIB0029|dote12491-cit-0029","first-page":"823","article-title":"Complications of endoscopic injection sclerotherapy: a review","volume":"82","author":"Schuman","year":"1987","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"10.1111\/dote.12491-BIB0030|dote12491-cit-0030","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0016-5085(87)91016-X","article-title":"Pericarditis: complication of esophageal sclerotherapy. A report of three cases","volume":"93","author":"Knauer","year":"1987","journal-title":"Gastroenterology"}],"container-title":["Diseases of the Esophagus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdote.12491","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/dote\/article-pdf\/30\/3\/1\/17727972\/dote12491.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T02:04:10Z","timestamp":1503626650000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/dote\/article-lookup\/doi\/10.1111\/dote.12491"}},"subtitle":["Complications of esophageal botox injections"],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":30,"URL":"https:\/\/doi.org\/10.1111\/dote.12491","archive":["Portico"],"relation":{},"ISSN":["1120-8694"],"issn-type":[{"value":"1120-8694","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]}}}