{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T20:09:13Z","timestamp":1785442153454,"version":"3.56.0"},"reference-count":94,"publisher":"Hindawi Limited","issue":"4","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":792,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Ther"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1111\/dth.12069","type":"journal-article","created":{"date-parts":[[2013,8,5]],"date-time":"2013-08-05T16:53:17Z","timestamp":1375721597000},"page":"337-346","source":"Crossref","is-referenced-by-count":54,"title":["Dermatological medication effects on male fertility"],"prefix":"10.1155","volume":"26","author":[{"given":"Jillian Wong","family":"Millsop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misha M.","family":"Heller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Eliason","sequence":"additional","affiliation":[{"name":"Department of Dermatology; University of Utah; Salt Lake City; Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny E.","family":"Murase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2013,8,5]]},"reference":[{"key":"10.1111\/dth.12069-BIB0001|dth12069-cit-0001","unstructured":"Organization of Teratology Information Specialists Paternal exposures and pregnancy 2002 http:\/\/www.otispregnancy.org\/"},{"key":"10.1111\/dth.12069-BIB0002|dth12069-cit-0002","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/pds.959","article-title":"Drug use among fathers around time of conception: two register based surveys from Denmark and The Netherlands","volume":"13","author":"Schirm","year":"2004","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1111\/dth.12069-BIB0003|dth12069-cit-0003","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.reprotox.2008.06.003","article-title":"Paternal exposure and counselling: experience of a Teratology Information Service","volume":"26","author":"De Santis","year":"2008","journal-title":"Reprod Toxicol"},{"key":"10.1111\/dth.12069-BIB0004|dth12069-cit-0004","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.reprotox.2010.01.008","article-title":"A pilot study of paternal drug exposure: the Motherisk experience","volume":"29","author":"Lee","year":"2010","journal-title":"Reprod Toxicol"},{"key":"10.1111\/dth.12069-BIB0005|dth12069-cit-0005","volume-title":"Drugs during pregnancy and lactation: treatment options and risk assessment","author":"Schaefer","year":"2007"},{"key":"10.1111\/dth.12069-BIB0006|dth12069-cit-0006","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1136\/ard.2009.127423","article-title":"Effects of TNF antagonists on sperm characteristics in patients with spondyloarthritis","volume":"69","author":"Villiger","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1111\/dth.12069-BIB0007|dth12069-cit-0007","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1610-0387.2007.06169.x","article-title":"Systemic dermatological treatment with relevance for male fertility","volume":"5","author":"Grunewald","year":"2007","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.1111\/dth.12069-BIB0008|dth12069-cit-0008","first-page":"577","article-title":"Effect of methotrexate on male fertility","volume":"49","author":"French","year":"2003","journal-title":"Can Fam Physician"},{"key":"10.1111\/dth.12069-BIB0009|dth12069-cit-0009","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/0190-9622(93)70270-4","article-title":"Methotrexate and reproduction in men: case report and recommendations","volume":"29","author":"Morris","year":"1993","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/dth.12069-BIB0010|dth12069-cit-0010","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1001\/archderm.1980.01640260091025","article-title":"Psoriasis, methotrexate, and oligospermia","volume":"116","author":"Sussman","year":"1980","journal-title":"Arch Dermatol"},{"key":"10.1111\/dth.12069-BIB0011|dth12069-cit-0011","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/jid.1959.161","article-title":"Morphologic and physiologic effects of chemotherapeutic agents in psoriasis","volume":"33","author":"Van Scott","year":"1959","journal-title":"J Invest Dermatol"},{"key":"10.1111\/dth.12069-BIB0012|dth12069-cit-0012","first-page":"271","article-title":"Teratospermic nach verabreichung von methotrexat","volume":"42","author":"Schoning","year":"1967","journal-title":"Z Haut-Geschl Krankh"},{"key":"10.1111\/dth.12069-BIB0013|dth12069-cit-0013","first-page":"80","article-title":"Fertility disturbances following treatment of patients with testicular tumours","volume":"13","author":"Weissbach","year":"1974","journal-title":"Urologe A"},{"key":"10.1111\/dth.12069-BIB0014|dth12069-cit-0014","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1001\/jama.1973.03220130040009","article-title":"Reversible drug-induced sterility in a patient with acute leukemia","volume":"223","author":"Hinkes","year":"1973","journal-title":"JAMA"},{"key":"10.1111\/dth.12069-BIB0015|dth12069-cit-0015","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1002\/1097-0142(19810515)47:10<2368::AID-CNCR2820471008>3.0.CO;2-D","article-title":"The effects of postoperative adjuvant chemotherapy and radiotherapy on testicular function in men undergoing treatment for soft tissue sarcoma","volume":"47","author":"Shamberger","year":"1981","journal-title":"Cancer"},{"key":"10.1111\/dth.12069-BIB0016|dth12069-cit-0016","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1159\/000251036","article-title":"Studies on human semen in topical corticosteroid-treated and in methotrexate-treated psoriatics","volume":"154","author":"Grunnet","year":"1977","journal-title":"Dermatologica"},{"key":"10.1111\/dth.12069-BIB0017|dth12069-cit-0017","first-page":"247","article-title":"Study of the seminal fluid in subjects treated with methotrexate","volume":"146","author":"De Luca","year":"1971","journal-title":"G Ital Dermatol Minerva Dermatol"},{"key":"10.1111\/dth.12069-BIB0018|dth12069-cit-0018","first-page":"498","article-title":"Andrologic examinations in the antimetabolite therapy of psoriasis","volume":"156","author":"Gunther","year":"1970","journal-title":"Dermatol Monatschr"},{"key":"10.1111\/dth.12069-BIB0019|dth12069-cit-0019","volume-title":"Prescribing in pregnancy","author":"Rubin","year":"2000"},{"key":"10.1111\/dth.12069-BIB0020|dth12069-cit-0020","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1001\/archinte.160.5.610","article-title":"The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation","volume":"160","author":"Janssen","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1111\/dth.12069-BIB0021|dth12069-cit-0021","volume-title":"Mild-to-moderate psoriasis","author":"Koo","year":"2009"},{"key":"10.1111\/dth.12069-BIB0022|dth12069-cit-0022","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.proghi.2004.04.001","article-title":"Cyclosporine A and adverse effects on organs: histochemical studies","volume":"39","author":"Rezzani","year":"2004","journal-title":"Prog Histochem Cytochem"},{"key":"10.1111\/dth.12069-BIB0023|dth12069-cit-0023","first-page":"301","article-title":"Exploring cyclosporine A-side effects and the protective role-played by antioxidants: the morphological and immunohistochemical studies","volume":"21","author":"Rezzani","year":"2006","journal-title":"Histol Histopathol"},{"key":"10.1111\/dth.12069-BIB0024|dth12069-cit-0024","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.intimp.2009.10.013","article-title":"Attenuation of cyclosporine A-induced testicular and spermatozoal damages associated with oxidative stress by ellagic acid","volume":"10","author":"Turk","year":"2010","journal-title":"Int Immunopharmacol"},{"key":"10.1111\/dth.12069-BIB0025|dth12069-cit-0025","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1007\/s003830050346","article-title":"Effect on cyclosporine on fertility in male rats","volume":"13","author":"Srinivas","year":"1998","journal-title":"Pediatr Surg Int"},{"key":"10.1111\/dth.12069-BIB0026|dth12069-cit-0026","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.theriogenology.2006.10.013","article-title":"Lycopene protects against cyclosporine A-induced testicular toxicity in rats","volume":"67","author":"Turk","year":"2007","journal-title":"Theriogenology"},{"key":"10.1111\/dth.12069-BIB0027|dth12069-cit-0027","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/j.intimp.2005.03.016","article-title":"Effects of cyclosporine on oxidant\/antioxidant status in rat ovary tissues: protective role of black grape extract","volume":"5","author":"Erg\u00fcder","year":"2005","journal-title":"Int Immunopharmacol"},{"key":"10.1111\/dth.12069-BIB0028|dth12069-cit-0028","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/jat.1245","article-title":"Protective effects of N-acetylcysteine on cyclosporine-A-induced nephrotoxicity","volume":"28","author":"Duru","year":"2008","journal-title":"J Appl Toxicol"},{"key":"10.1111\/dth.12069-BIB0029|dth12069-cit-0029","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.toxlet.2004.03.002","article-title":"The protective effect of taurine against cyclosporine A-induced oxidative stress and hepatotoxicity in rats","volume":"151","author":"Hagar","year":"2004","journal-title":"Toxicol Lett"},{"key":"10.1111\/dth.12069-BIB0030|dth12069-cit-0030","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1439-0272.1995.tb01092.x","article-title":"Histological and endocrinological investigations of cyclosporine effects on the rate testis","volume":"27","author":"Iwasaki","year":"1995","journal-title":"Andrologia"},{"key":"10.1111\/dth.12069-BIB0031|dth12069-cit-0031","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0015-0282(16)49462-8","article-title":"Effect of cyclosporine A in male autoimmune infertility","volume":"46","author":"Bouloux","year":"1986","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0032|dth12069-cit-0032","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/S0022-5347(17)38318-0","article-title":"Male fertility in cyclosporine-treated renal transplant patients","volume":"145","author":"Haberman","year":"1991","journal-title":"J Urol"},{"key":"10.1111\/dth.12069-BIB0033|dth12069-cit-0033","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/247553030915a00105","article-title":"Purine synthesis inhibitors, 6-thioguanine and azathioprine: forgotten treatment options in psoriasis and psoriatic arthritis","volume":"15","author":"Nguyen","year":"2009","journal-title":"Psoriasis Forum"},{"key":"10.1111\/dth.12069-BIB0034|dth12069-cit-0034","first-page":"167","volume-title":"Comprehensive dermatologic drug therapy","author":"Wolverton","year":"2007"},{"key":"10.1111\/dth.12069-BIB0035|dth12069-cit-0035","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1080\/00365520510011597","article-title":"Effects of 6-mercaptopurine treatment on sperm production and reproductive performance: a study in male mice","volume":"40","author":"Ligumsky","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/dth.12069-BIB0036|dth12069-cit-0036","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1053\/gast.2001.28692","article-title":"Azathioprine treatment and male fertility in inflammatory bowel disease","volume":"121","author":"Dejaco","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1111\/dth.12069-BIB0037|dth12069-cit-0037","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.trim.2009.10.001","article-title":"The influence of immunosuppressants on the fertility of males who undergo renal transplantation and on the immune function of their offspring","volume":"22","author":"Xu","year":"2009","journal-title":"Transpl Immunol"},{"issue":"Suppl. 1","key":"10.1111\/dth.12069-BIB0038|dth12069-cit-0038","first-page":"111","article-title":"Effect of dexamethasone on germ cell apoptosis in the contralateral testis after testicular ischemia-reperfusion injury in the rat","volume":"85","author":"Mogilner","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0039|dth12069-cit-0039","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1210\/en.133.6.2568","article-title":"Expression, regulation, and production of tumor necrosis factor-alpha in mouse testicular interstitial macrophages in vitro","volume":"133","author":"Xiong","year":"1993","journal-title":"Endocrinology"},{"key":"10.1111\/dth.12069-BIB0040|dth12069-cit-0040","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/j.fertnstert.2004.11.068","article-title":"Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model","volume":"83","author":"Said","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0041|dth12069-cit-0041","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1530\/eje.0.1510629","article-title":"Tumor necrosis factor-\u03b1 (TNF-\u03b1) promotes cell survival during spermatogenesis, and this effect can be blocked by infliximab, a TNF-\u03b1 antagonist","volume":"151","author":"Suominen","year":"2004","journal-title":"Eur J Endocrinol"},{"key":"10.1111\/dth.12069-BIB0042|dth12069-cit-0042","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1210\/en.2007-1064","article-title":"Exploring human testicular peritubular cells: identification of secretory products and regulation by tumor necrosis factor-\u03b1","volume":"149","author":"Schell","year":"2008","journal-title":"Endocrinology"},{"key":"10.1111\/dth.12069-BIB0043|dth12069-cit-0043","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/j.1939-4640.1989.tb00100.x","article-title":"The effect of tumor necrosis factor on human sperm motility in vitro","volume":"10","author":"Eisermann","year":"1989","journal-title":"J Androl"},{"key":"10.1111\/dth.12069-BIB0044|dth12069-cit-0044","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1046\/j.1365-2605.1997.00062.x","article-title":"Effect of tumour necrosis factor-\u03b1 (TNF-\u03b1) and interferon-\u03b3 (IFN-\u03b3) on human sperm motility, viability and motion parameters","volume":"20","author":"Estrada","year":"1997","journal-title":"Int J Androl"},{"key":"10.1111\/dth.12069-BIB0045|dth12069-cit-0045","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s10875-007-9071-5","article-title":"Effects of tumour necrosis factor-\u03b1 on human sperm motility and apoptosis","volume":"27","author":"Perdichizzi","year":"2007","journal-title":"J Clin Immunol"},{"key":"10.1111\/dth.12069-BIB0046|dth12069-cit-0046","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3899\/jrheum.080554","article-title":"Fertility and reproduction in male patients with ankylosing spondylitis treated with infliximab","volume":"36","author":"Paschou","year":"2009","journal-title":"J Rheumatol"},{"key":"10.1111\/dth.12069-BIB0047|dth12069-cit-0047","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/jez.a.264","article-title":"Impairment of spermatogenesis and enhancement of testicular germ cell apoptosis induced by exogenous all-trans-retinoic acid in adult lizard Podarcis sicula","volume":"305","author":"Comitato","year":"2006","journal-title":"J Exp Zool A Comp Exp Biol"},{"key":"10.1111\/dth.12069-BIB0048|dth12069-cit-0048","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1468-3083.2006.01573.x","article-title":"Effects of acitretin on spermatogenesis of rats","volume":"20","author":"Sengor","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/dth.12069-BIB0049|dth12069-cit-0049","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1159\/000063893","article-title":"Is there a reproductive safety risk in male patients treated with acitretin (neotigason\/soriatane)?","volume":"205","author":"Geiger","year":"2002","journal-title":"Dermatology"},{"key":"10.1111\/dth.12069-BIB0050|dth12069-cit-0050","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/j.1439-0272.1990.tb02034.x","article-title":"Andrological investigations in men treated with acitretin (Ro 10-1670)","volume":"22","author":"Parsch","year":"1990","journal-title":"Andrologia"},{"key":"10.1111\/dth.12069-BIB0051|dth12069-cit-0051","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1529-8019.2008.00175.x","article-title":"New and emerging treatments in dermatology: acne","volume":"21","author":"Katsambas","year":"2008","journal-title":"Dermatol Ther"},{"key":"10.1111\/dth.12069-BIB0052|dth12069-cit-0052","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0190-9622(96)90462-4","article-title":"Oral 13-cis retinoic acid is superior to 9-cis retinoic acid in sebosuppression in human beings","volume":"34","author":"Geiger","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/dth.12069-BIB0053|dth12069-cit-0053","doi-asserted-by":"crossref","first-page":"2154","DOI":"10.1038\/sj.jid.5700418","article-title":"Isotretinoin revisited: pluripotent effects on human sebaceous gland cells","volume":"126","author":"Zouboulis","year":"2006","journal-title":"J Invest Dermatol"},{"key":"10.1111\/dth.12069-BIB0054|dth12069-cit-0054","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1038\/sj.jid.5700289","article-title":"13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes","volume":"126","author":"Nelson","year":"2006","journal-title":"J Invest Dermatol"},{"key":"10.1111\/dth.12069-BIB0055|dth12069-cit-0055","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2340\/00015555-1325","article-title":"Treatment of severe acne with low-dose isotretinoin","volume":"92","author":"Mehra","year":"2012","journal-title":"Acta Derm Venereol"},{"issue":"4 Pt 2 Suppl.","key":"10.1111\/dth.12069-BIB0056|dth12069-cit-0056","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/S0190-9622(82)70054-4","article-title":"Toxicology, carcinogenicity, and teratogenicity of some orally administered retinoids","volume":"6","author":"Kamm","year":"1982","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/dth.12069-BIB0057|dth12069-cit-0057","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0300-483X(80)90015-3","article-title":"Atrophy induced in the tubules of the testes of Syrian hamsters by two retinoids","volume":"17","author":"Stinson","year":"1980","journal-title":"Toxicology"},{"key":"10.1111\/dth.12069-BIB0058|dth12069-cit-0058","first-page":"245","article-title":"Light microscopic studies of spermatogenesis in rats following the administration of high doses of 13-cis-retinoic acid","volume":"60","author":"Kuhlwein","year":"1985","journal-title":"Z Hautkr"},{"key":"10.1111\/dth.12069-BIB0059|dth12069-cit-0059","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1439-0272.1987.tb01915.x","article-title":"Spermatological investigations in patients treated with etretinate and isotretinoin","volume":"19","author":"Torok","year":"1987","journal-title":"Andrologia"},{"key":"10.1111\/dth.12069-BIB0060|dth12069-cit-0060","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/978-3-642-68023-6_57","volume-title":"Retinoids: advances in basic research and therapy","author":"Schill","year":"1981"},{"key":"10.1111\/dth.12069-BIB0061|dth12069-cit-0061","first-page":"281","article-title":"13-cis-Retinsaure und spermatogenese","volume":"36","author":"Vogt","year":"1985","journal-title":"Hautarzt"},{"key":"10.1111\/dth.12069-BIB0062|dth12069-cit-0062","first-page":"407","volume-title":"Retinoids: new trends in research and therapy","author":"Torok","year":"1985"},{"key":"10.1111\/dth.12069-BIB0063|dth12069-cit-0063","first-page":"427","article-title":"[Isotretinoin treatment of acne conglobata. Andrologic follow-up]","volume":"110","author":"Hoting","year":"1992","journal-title":"Fortschr Med"},{"issue":"4","key":"10.1111\/dth.12069-BIB0064|dth12069-cit-0064","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0890-6238(91)90094-V","article-title":"Decreased fertility in male rats administered the 5 alpha-reductase inhibitor, finasteride, is due to deficits in copulatory plug formation","volume":"5","author":"Cukierski","year":"1991","journal-title":"Reprod Toxicol"},{"issue":"4","key":"10.1111\/dth.12069-BIB0065|dth12069-cit-0065","first-page":"353","article-title":"Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5 alpha-reductase inhibitor","volume":"5","author":"Wise","year":"1991","journal-title":"Reprod Toxicol"},{"key":"10.1111\/dth.12069-BIB0066|dth12069-cit-0066","doi-asserted-by":"crossref","first-page":"849 e17","DOI":"10.1016\/j.fertnstert.2007.08.026","article-title":"Propecia-induced spermatogenic failure: a report of two cases","volume":"90","author":"Liu","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0067|dth12069-cit-0067","first-page":"2469","article-title":"Finasteride. Does it affect spermatogenesis and pregnancy?","volume":"47","author":"Pole","year":"2001","journal-title":"Can Fam Physician"},{"key":"10.1111\/dth.12069-BIB0068|dth12069-cit-0068","first-page":"139","article-title":"Effect of finasteride (Proscar MSD) on seminal composition, prostate function and fertility in male dogs","volume":"51","author":"Iguer-Ouada","year":"1997","journal-title":"J Reprod Fertil Suppl"},{"key":"10.1111\/dth.12069-BIB0069|dth12069-cit-0069","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0022-5347(05)68270-5","article-title":"Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men","volume":"162","author":"Overstreet","year":"1999","journal-title":"J Urol"},{"key":"10.1111\/dth.12069-BIB0070|dth12069-cit-0070","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1590\/S0041-87812004000400009","article-title":"Finasteride-associated male infertility","volume":"59","author":"Glina","year":"2004","journal-title":"Rev Hosp Clin Fac Med S Paulo"},{"key":"10.1111\/dth.12069-BIB0071|dth12069-cit-0071","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.fertnstert.2010.12.061","article-title":"Finasteride-induced secondary infertility associated with sperm DNA damage","volume":"95","author":"Tu","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0072|dth12069-cit-0072","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/1523-1747.ep12472325","article-title":"Spironolactone directly inhibits proliferation of cultured human facial sebocytes and acts antagonistically to testosterone and 5 alpha-hydroxytestosterone in vitro","volume":"100","author":"Akamatsu","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1111\/dth.12069-BIB0073|dth12069-cit-0073","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1095\/biolreprod27.4.771","article-title":"Effects of spironolactone (aldosterone antagonist) on electrolyte and water content of the cauda epididymis and fertility of male rats","volume":"27","author":"Wong","year":"1982","journal-title":"Biol Reprod"},{"key":"10.1111\/dth.12069-BIB0074|dth12069-cit-0074","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1001\/jama.1965.03090020077026","article-title":"Spironolactone therapy and gynecomastia","volume":"193","author":"Clark","year":"1965","journal-title":"JAMA"},{"key":"10.1111\/dth.12069-BIB0075|dth12069-cit-0075","doi-asserted-by":"crossref","first-page":"685","DOI":"10.7326\/0003-4819-69-4-685","article-title":"Aldosteronism in hypertension. The spironolactone response test","volume":"69","author":"Spark","year":"1968","journal-title":"Ann Intern Med"},{"key":"10.1111\/dth.12069-BIB0076|dth12069-cit-0076","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1001\/archinte.1972.03650060047008","article-title":"Spironolactone and hydrochlorothiazide in essential hypertension","volume":"130","author":"Adlin","year":"1972","journal-title":"Arch Intern Med"},{"key":"10.1111\/dth.12069-BIB0077|dth12069-cit-0077","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1001\/jama.1974.03230180016005","article-title":"Treatment of low-renin essential hypertension. Comparison of spironolactone and a hydrochlorothiazide-triamterene combination","volume":"227","author":"Douglas","year":"1974","journal-title":"JAMA"},{"key":"10.1111\/dth.12069-BIB0078|dth12069-cit-0078","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1210\/jcem-45-2-255","article-title":"Gynecomastia and semen abnormalities induced by spironolactone in normal men","volume":"45","author":"Caminos-Torres","year":"1977","journal-title":"J Endocrinol Metab"},{"key":"10.1111\/dth.12069-BIB0079|dth12069-cit-0079","first-page":"1","article-title":"Protective effect of minocycline on dexamethasone induced testicular germ cell apoptosis in mice","volume":"13","author":"Orazizadeh","year":"2009","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1111\/dth.12069-BIB0080|dth12069-cit-0080","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.urology.2011.08.062","article-title":"Empirical treatment of low-level leukocytospermia with doxycycline in male infertility patients","volume":"78","author":"Hamada","year":"2011","journal-title":"Urology"},{"key":"10.1111\/dth.12069-BIB0081|dth12069-cit-0081","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1093\/humrep\/13.7.1878","article-title":"Effects of co-trimoxazole, erythromycin, amoxicillin, tetracycline and chloroquine on sperm function in vitro","volume":"13","author":"Hargreaves","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1111\/dth.12069-BIB0082|dth12069-cit-0082","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0015-0282(16)57309-9","article-title":"Antibiotic therapy and leukocytospermia: a prospective, randomized, controlled study","volume":"63","author":"Yanushpolsky","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0083|dth12069-cit-0083","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1365-2605.1984.tb00795.x","article-title":"A controlled trial of the use of erythromycin for men with asthenospermia","volume":"7","author":"Baker","year":"1984","journal-title":"Int J Androl"},{"key":"10.1111\/dth.12069-BIB0084|dth12069-cit-0084","first-page":"63","article-title":"Chloroquine reduces fertilizing capacity of epididyma sperm in rats","volume":"27","author":"Adeeko","year":"1998","journal-title":"Afr J Med Med Sci"},{"key":"10.1111\/dth.12069-BIB0085|dth12069-cit-0085","first-page":"118","article-title":"An investigation into the effects of chloroquine on fertility of male rats","volume":"12","author":"Okanlawon","year":"1993","journal-title":"West Afr J Med"},{"key":"10.1111\/dth.12069-BIB0086|dth12069-cit-0086","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1001\/archinte.1982.00340250097015","article-title":"Ketoconazole blocks testosterone synthesis","volume":"142","author":"Pont","year":"1982","journal-title":"Arch Intern Med"},{"key":"10.1111\/dth.12069-BIB0087|dth12069-cit-0087","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/j.1939-4640.1992.tb00298.x","article-title":"The effect of ketoconazole on endocrine and reproductive parameters in male mice and rats","volume":"13","author":"Heckman","year":"1992","journal-title":"J Androl"},{"key":"10.1111\/dth.12069-BIB0088|dth12069-cit-0088","first-page":"55","article-title":"Effects of ketoconazole (an imidazole antifungal agent) on the fertility and reproductive function of male mice","volume":"25","author":"Joshi","year":"1994","journal-title":"Acta Eur Fertil"},{"key":"10.1111\/dth.12069-BIB0089|dth12069-cit-0089","first-page":"1028","article-title":"Asthenospermia in hay fever patients improved by stopping treatment with histamine H1 receptor antagonists. International Journal of","volume":"13","author":"Hayashi","year":"2006","journal-title":"Urology"},{"key":"10.1111\/dth.12069-BIB0090|dth12069-cit-0090","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2515\/therapie:2004031","article-title":"Two cases of gynaecomastia with cetirizine, a second-generation antihistamine","volume":"59","author":"Louis","year":"2004","journal-title":"Therapie"},{"key":"10.1111\/dth.12069-BIB0091|dth12069-cit-0091","first-page":"481","article-title":"Influence of histamine and H1-receptor antagonists on ejaculated human spermatozoa: role of intrasperm Ca2+","volume":"42","author":"Gupta","year":"2004","journal-title":"Indian J Exp Biol"},{"key":"10.1111\/dth.12069-BIB0092|dth12069-cit-0092","first-page":"291","article-title":"Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells","volume":"4","author":"Cayan","year":"2002","journal-title":"Asian J Androl"},{"key":"10.1111\/dth.12069-BIB0093|dth12069-cit-0093","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/S0015-0282(16)57992-8","article-title":"New treatment of idiopathic severe oligozoospermia with mast cell blocker: results of single-blind study","volume":"64","author":"Yamamoto","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1111\/dth.12069-BIB0094|dth12069-cit-0094","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/014850100262290","article-title":"The use of ebastine, a mast cell blocker, for treatment of oligozoospermia","volume":"44","author":"Matsuki","year":"2000","journal-title":"Arch Androl"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdth.12069","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/dth.12069\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T01:37:58Z","timestamp":1715823478000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.12069"}},"subtitle":["Medication effects on male fertility"],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":94,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,7]]}},"URL":"https:\/\/doi.org\/10.1111\/dth.12069","relation":{},"ISSN":["1396-0296"],"issn-type":[{"value":"1396-0296","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}