{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:17:59Z","timestamp":1790702279000,"version":"4.1.0"},"reference-count":42,"publisher":"Hindawi Limited","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":730,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatol Ther"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1111\/dth.12085","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T10:22:34Z","timestamp":1444731754000},"page":"404-410","source":"Crossref","is-referenced-by-count":28,"title":["Oral retinoids and plasma lipids"],"prefix":"10.1155","volume":"26","author":[{"given":"Jessica S.","family":"Lilley","sequence":"first","affiliation":[{"name":"Section of Prevention of Cardiovascular Disease; Vanderbilt University Medical Center; Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MacRae F.","family":"Linton","sequence":"additional","affiliation":[{"name":"Section of Prevention of Cardiovascular Disease; Vanderbilt University Medical Center; Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Fazio","sequence":"additional","affiliation":[{"name":"Section of Prevention of Cardiovascular Disease; Vanderbilt University Medical Center; Nashville Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","published-online":{"date-parts":[[2013,10,4]]},"reference":[{"key":"10.1111\/dth.12085-BIB0001|dth12085-cit-0001","doi-asserted-by":"crossref","first-page":"S417","DOI":"10.1194\/jlr.R800039-JLR200","article-title":"The outer frontier: the importance of lipid metabolism in the skin","volume":"50","author":"Feingold","year":"2009","journal-title":"J Lipid Res"},{"key":"10.1111\/dth.12085-BIB0002|dth12085-cit-0002","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/MOL.0b013e3281527914","article-title":"GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons","volume":"18","author":"Young","year":"2007","journal-title":"Curr Opin Lipidol"},{"key":"10.1111\/dth.12085-BIB0003|dth12085-cit-0003","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/S0022-2275(20)34418-7","article-title":"Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol","volume":"25","author":"Goldstein","year":"1984","journal-title":"J Lipid Res"},{"key":"10.1111\/dth.12085-BIB0004|dth12085-cit-0004","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","article-title":"Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)","volume":"285","author":"Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults","year":"2001","journal-title":"JAMA"},{"key":"10.1111\/dth.12085-BIB0005|dth12085-cit-0005","doi-asserted-by":"crossref","first-page":"7B","DOI":"10.1016\/S0002-9149(98)00031-9","article-title":"Hypertriglyceridemia as a cardiovascular risk factor","volume":"81","author":"Austin","year":"1998","journal-title":"Am J Cardiol"},{"key":"10.1111\/dth.12085-BIB0006|dth12085-cit-0006","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/00004836-200301000-00016","article-title":"Issues in hyperlipidemic pancreatitis","volume":"36","author":"Yadav","year":"2003","journal-title":"J Clin Gastroenterol"},{"key":"10.1111\/dth.12085-BIB0007|dth12085-cit-0007","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/01.CIR.79.1.8","article-title":"High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies","volume":"79","author":"Gordon","year":"1989","journal-title":"Circulation"},{"key":"10.1111\/dth.12085-BIB0008|dth12085-cit-0008","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1124\/pr.58.3.1","article-title":"Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis","volume":"58","author":"Kontush","year":"2006","journal-title":"Pharmacol Rev"},{"key":"10.1111\/dth.12085-BIB0009|dth12085-cit-0009","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1056\/NEJMoa1107579","article-title":"Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy","volume":"365","author":"Boden","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1111\/dth.12085-BIB0010|dth12085-cit-0010","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1194\/jlr.R024075","article-title":"Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk","volume":"53","author":"Barter","year":"2012","journal-title":"J Lipid Res"},{"key":"10.1111\/dth.12085-BIB0011|dth12085-cit-0011","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1194\/jlr.R700013-JLR200","article-title":"Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis","volume":"48","author":"Feingold","year":"2007","journal-title":"J Lipid Res"},{"key":"10.1111\/dth.12085-BIB0012|dth12085-cit-0012","doi-asserted-by":"crossref","first-page":"582","DOI":"10.7326\/0003-4819-136-8-200204160-00007","article-title":"High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study","volume":"136","author":"Rodondi","year":"2002","journal-title":"Ann Intern Med"},{"key":"10.1111\/dth.12085-BIB0013|dth12085-cit-0013","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1073\/pnas.90.6.2160","article-title":"Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers","volume":"90","author":"Keller","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/dth.12085-BIB0014|dth12085-cit-0014","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1210\/endo.137.1.8536636","article-title":"Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat","volume":"137","author":"Braissant","year":"1996","journal-title":"Endocrinology"},{"key":"10.1111\/dth.12085-BIB0015|dth12085-cit-0015","doi-asserted-by":"crossref","first-page":"S158","DOI":"10.1067\/mjd.2001.113718","article-title":"Regulation of lipid and lipoprotein metabolism by retinoids","volume":"45","author":"Staels","year":"2001","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/dth.12085-BIB0016|dth12085-cit-0016","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1610-0387.2011.07637.x","article-title":"The impact of oral vitamin A derivatives on lipid metabolism - what recommendations can be derived for dealing with this issue in the daily dermatological practice?","volume":"9","author":"Klor","year":"2011","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.1111\/dth.12085-BIB0017|dth12085-cit-0017","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/sj.jid.5700944","article-title":"PPAR and LXR activators regulate ABCA12 expression in human keratinocytes","volume":"128","author":"Jiang","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1111\/dth.12085-BIB0018|dth12085-cit-0018","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/MOL.0b013e32832b3f4c","article-title":"FoxO1 and hepatic lipid metabolism","volume":"20","author":"Sparks","year":"2009","journal-title":"Curr Opin Lipidol"},{"key":"10.1111\/dth.12085-BIB0019|dth12085-cit-0019","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1001\/archderm.142.8.1016","article-title":"A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris","volume":"142","author":"Zane","year":"2006","journal-title":"Arch Dermatol"},{"key":"10.1111\/dth.12085-BIB0020|dth12085-cit-0020","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/095466301750163509","article-title":"Analysis of laboratory data in acne patients treated with isotretinoin: is there really a need to perform routine laboratory tests?","volume":"12","author":"Alcalay","year":"2001","journal-title":"J Dermatolog Treat"},{"key":"10.1111\/dth.12085-BIB0021|dth12085-cit-0021","first-page":"562","article-title":"Chemoprevention of nonmelanoma skin cancer with systemic retinoids: practical dosing and management of adverse effects","volume":"32","author":"Otley","year":"2006","journal-title":"Dermatol Surg"},{"key":"10.1111\/dth.12085-BIB0022|dth12085-cit-0022","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/j.1365-2133.1993.tb03336.x","article-title":"Isotretinoin therapy for acne vulgaris: a re-evaluation of the need for measurements of plasma lipids and liver function tests","volume":"129","author":"Barth","year":"1993","journal-title":"Br J Dermatol"},{"key":"10.1111\/dth.12085-BIB0023|dth12085-cit-0023","unstructured":"Targretin package insert http:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/1999\/21055lbl.pdf"},{"issue":"1","key":"10.1111\/dth.12085-BIB0024|dth12085-cit-0024","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/bjd.12042","article-title":"U.K. consensus statement on safe clinical prescribing of bexarotene for patients with cutaneous T-cell lymphoma","volume":"168","author":"Scarisbrick","year":"2013","journal-title":"Br J Dermatol"},{"key":"10.1111\/dth.12085-BIB0025|dth12085-cit-0025","first-page":"1855","article-title":"Marked hyperlipidemia and pancreatitis associated with isotretinoin therapy","volume":"87","author":"McCarter","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/dth.12085-BIB0026|dth12085-cit-0026","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jacl.2012.05.002","article-title":"Prevalence of lipid abnormalities in the United States: the National Health and Nutrition Examination Survey 2003-2006","volume":"6","author":"Toth","year":"2012","journal-title":"J Clin Lipidol"},{"key":"10.1111\/dth.12085-BIB0027|dth12085-cit-0027","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/humu.20105","article-title":"LDL-receptor mutations in Europe","volume":"24","author":"Dedoussis","year":"2004","journal-title":"Hum Mutat"},{"key":"10.1111\/dth.12085-BIB0028|dth12085-cit-0028","first-page":"S1","article-title":"Strategies for reducing cardiovascular risk in patients with hypertriglyceridemia","volume":"56","author":"Gorkin","year":"2007","journal-title":"J Fam Pract"},{"key":"10.1111\/dth.12085-BIB0029|dth12085-cit-0029","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","article-title":"Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1111\/dth.12085-BIB0030|dth12085-cit-0030","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.2165\/00003495-200666150-00005","article-title":"Familial dyslipidaemias: an overview of genetics, pathophysiology and management","volume":"66","author":"Hachem","year":"2006","journal-title":"Drugs"},{"key":"10.1111\/dth.12085-BIB0031|dth12085-cit-0031","first-page":"1060","article-title":"Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases","volume":"320","author":"Eckel","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1111\/dth.12085-BIB0032|dth12085-cit-0032","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/0002-9378(92)91370-P","article-title":"Comparison of transdermal and oral estrogen-progestin replacement therapy: effects on serum lipids and lipoproteins","volume":"166","author":"Crook","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1111\/dth.12085-BIB0033|dth12085-cit-0033","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1161\/CIR.0b013e3182160726","article-title":"Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association","volume":"123","author":"Miller","year":"2011","journal-title":"Circulation"},{"key":"10.1111\/dth.12085-BIB0034|dth12085-cit-0034","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.clnu.2008.02.001","article-title":"Omega-3 fatty acid containing diets decrease plasma triglyceride concentrations in mice by reducing endogenous triglyceride synthesis and enhancing the blood clearance of triglyceride-rich particles","volume":"27","author":"Qi","year":"2008","journal-title":"Clin Nutr"},{"key":"10.1111\/dth.12085-BIB0035|dth12085-cit-0035","doi-asserted-by":"crossref","first-page":"1645S","DOI":"10.1093\/ajcn\/65.5.1645S","article-title":"n-3 fatty acids and serum lipoproteins: human studies","volume":"65","author":"Harris","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1111\/dth.12085-BIB0036|dth12085-cit-0036","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0140-6736(99)07072-5","article-title":"Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico","volume":"354","author":"GISSI-Prevenzione Investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico)","year":"1999","journal-title":"Lancet"},{"key":"10.1111\/dth.12085-BIB0037|dth12085-cit-0037","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S0140-6736(07)60527-3","article-title":"Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis","volume":"369","author":"Yokoyama","year":"2007","journal-title":"Lancet"},{"key":"10.1111\/dth.12085-BIB0038|dth12085-cit-0038","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1586\/erc.12.56","article-title":"A new pure omega-3 eicosapentaenoic acid ethyl ester (AMR101) for the management of hypertriglyceridemia: the MARINE trial","volume":"10","author":"Jacobson","year":"2012","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"10.1111\/dth.12085-BIB0039|dth12085-cit-0039","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.amjcard.2012.05.031","article-title":"Efficacy and safety of eicosapentaenoic acid ethyl ester (AMR101) therapy in statin-treated patients with persistent high triglycerides (from the ANCHOR study)","volume":"110","author":"Ballantyne","year":"2012","journal-title":"Am J Cardiol"},{"key":"10.1111\/dth.12085-BIB0040|dth12085-cit-0040","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1210\/jc.2011-3213","article-title":"Evaluation and treatment of hypertriglyceridemia: an endocrine society clinical practice guideline","volume":"97","author":"Berglund","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1111\/dth.12085-BIB0041|dth12085-cit-0041","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jacl.2012.04.003","article-title":"Treatment options for the management of hypertriglyceridemia: strategies based on the best-available evidence","volume":"6","author":"Maki","year":"2012","journal-title":"J Clin Lipidol"},{"key":"10.1111\/dth.12085-BIB0042|dth12085-cit-0042","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1177\/0009922808330780","article-title":"Novel management of isotretinoin-induced hypertriglyceridemia in an adolescent with severe acne","volume":"48","author":"Beach","year":"2009","journal-title":"Clin Pediatr (Phila)"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdth.12085","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/dth.12085\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T18:00:30Z","timestamp":1671818430000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.12085"}},"subtitle":["Retinoids and lipids"],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,9]]}},"URL":"https:\/\/doi.org\/10.1111\/dth.12085","archive":["Portico"],"relation":{},"ISSN":["1396-0296"],"issn-type":[{"value":"1396-0296","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]}}}