{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T15:04:45Z","timestamp":1764169485458,"version":"3.46.0"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Tofacitinib is a Janus Kinase 3 inhibitor that is used in the treatment of alopecia areata. We recommended our alopecia areata patients to discontinue their tofacitinib treatment during the COVID\u201019 pandemic for an average of 80\u2009days. We aimed to evaluate the drug use and the SARS\u2010CoV\u20102 infection status of alopecia areata patients; and the relationships of recurrence to age, gender, treatment duration, and tofacitinib discontinuation. One\u2010hundred and ninety\u2010one (61.4%) patients were off the drug and 120 (38.6%) were on therapy during the pandemic. The relationship between drug discontinuation due to the COVID\u201019 pandemic and recurrence was statistically significant (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.001). Statistically significant relationships of age (\n                    <jats:italic>P<\/jats:italic>\n                    = .013) and treatment duration (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.001) to recurrence were also found. The change in the SALT score differed between the patients on therapy and off therapy during the pandemic (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.001). A significant negative correlation was found between the change in the SALT score and treatment duration: the spearman correlation test\n                    <jats:italic>P<\/jats:italic>\n                    = .018. We concluded that the patients may continue to the tofacitinib therapy during the rest of the COVID\u201019 pandemic if the benefit outweighed the risk.\n                  <\/jats:p>","DOI":"10.1111\/dth.14746","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T23:34:49Z","timestamp":1610062489000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Evaluation of the alopecia areata patients on tofacitinib treatment during the COVID\u201019 pandemic"],"prefix":"10.1155","volume":"34","author":[{"given":"\u00d6zge","family":"A\u015fk\u0131n","sequence":"first","affiliation":[{"name":"Cerrahpa\u015fa Medical Faculty, Department of Dermatology and Venerology \u0130stanbul University\u2010Cerrahpa\u015fa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4211-2276","authenticated-orcid":false,"given":"Defne","family":"\u00d6zkoca","sequence":"additional","affiliation":[{"name":"Cerrahpa\u015fa Medical Faculty, Department of Dermatology and Venerology \u0130stanbul University\u2010Cerrahpa\u015fa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011fba Kevser","family":"Uzun\u00e7akmak","sequence":"additional","affiliation":[{"name":"Cerrahpa\u015fa Medical Faculty, Department of Dermatology and Venerology \u0130stanbul University\u2010Cerrahpa\u015fa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Server","family":"Serdaro\u011flu","sequence":"additional","affiliation":[{"name":"Cerrahpa\u015fa Medical Faculty, Department of Dermatology and Venerology \u0130stanbul University\u2010Cerrahpa\u015fa  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12844"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.04.1141"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/14728214.2018.1444750"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2020.03.019"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15937"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555577296298"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2008017"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.09.007"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2020.52.2.154"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15383"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.89790"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13684"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.14746","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dth.14746","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.14746","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T14:58:29Z","timestamp":1764169109000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.14746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,18]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/dth.14746"],"URL":"https:\/\/doi.org\/10.1111\/dth.14746","archive":["Portico"],"relation":{},"ISSN":["1396-0296"],"issn-type":[{"type":"print","value":"1396-0296"}],"subject":[],"published":{"date-parts":[[2021,1,18]]},"assertion":[{"value":"2020-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14746"}}