{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:11:28Z","timestamp":1781763088447,"version":"3.54.5"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T00:00:00Z","timestamp":1613174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Beta\u20102 adrenergic receptors are the only subgroup of beta\u2010adrenergic receptors expressed in the membrane of large cells, including skin keratinocytes, fibroblasts, and melanocytes. Alterations in the function or concentration of \u03b22 adrenoreceptors related to keratinocytes are associated with some skin conditions. Some findings suggest the role of \u03b22 adrenoreceptors in maintaining the function and integrity of the epidermis. Beta\u2010receptor antagonists can be systemically and topically effective in healing hemangioma, paronychia, vasculitis ulcer, tufted angioma, acute and chronic wounds. Most studies with a strong design on this subject deal with the systemic form, but recently, numerous case and group reports and smaller studies have focused on topical forms, especially topical timolol. The present comprehensive review study surveys the role of topical timolol in acute and chronic wound healing in the field of dermatology.<\/jats:p>","DOI":"10.1111\/dth.14847","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T21:30:33Z","timestamp":1612560633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The role of topical timolol in wound healing and the treatment of vascular lesions: A narrative review"],"prefix":"10.1155","volume":"34","author":[{"given":"Azadeh","family":"Goodarzi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Rasool Akram Medical Complex Iran University of Medical Sciences (IUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samaneh","family":"Mozafarpoor","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Skin Disease and Leishmaniasis Research Center Isfahan University 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