{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:01:59Z","timestamp":1779260519824,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:00:00Z","timestamp":1613692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Masks are essential for COVID\u201019 prevention, but recently they were suggested to modify cutaneous facial microenvironment and trigger facial dermatoses. To evaluate mask\u2010related rosacea and acne (maskne) in untreated patients during lockdown. In this multi\u2010center, real\u2010life, observational prospective study, we enrolled stable, untreated acne and rosacea patients that wore masks during lockdown at least 6 h\/day. They underwent two teledermatological consultations, at the baseline and after 6\u2009weeks. Clinical, pharmacological, and psychological data were recorded. A total 66 patients, 30 (median age: 34.0 [30.25\u201029.75] yoa) with acne and 36 patients (median age: 48 [43\u201054] years) with rosacea, were enrolled in this study. After 6\u2009weeks of mask and quarantine, patients with acne displayed an increased Global Acne Grading Scale (GAGS) score in mask\u2010related areas (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001). Likewise, after 6\u2009weeks of mask and quarantine, patients with rosacea displayed a worsen in both physican (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001) and patient (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001) reported outcomes. Remarkably, patients reported also a statistically significant decrease in their quality of life (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001). Masks appear to trigger both acne and rosacea flares. Additional studies are needed to generate evidence and inform clinical decision\u2010making.\n                  <\/jats:p>","DOI":"10.1111\/dth.14848","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T20:07:16Z","timestamp":1612555636000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["COVID\u201019 related masks increase severity of both acne (maskne) and rosacea (mask rosacea): Multi\u2010center, real\u2010life, telemedical, and observational prospective study"],"prefix":"10.1155","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2390-6505","authenticated-orcid":false,"given":"Giovanni","family":"Damiani","sequence":"first","affiliation":[{"name":"Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi  Milan Italy"},{"name":"Department of Biomedical, Surgical, and Dental Sciences University of Milan  Milan Italy"},{"name":"Department of Pharmaceutical and Pharmacological Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7298-4446","authenticated-orcid":false,"given":"Laura C.","family":"Gironi","sequence":"additional","affiliation":[{"name":"AOU Maggiore della Carit\u00e0  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5321-0584","authenticated-orcid":false,"given":"Ayman","family":"Grada","sequence":"additional","affiliation":[{"name":"Department of Dermatology Boston University School of Medicine  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9971-9151","authenticated-orcid":false,"given":"Khalaf","family":"Kridin","sequence":"additional","affiliation":[{"name":"L\u00fcbeck Institute of Experimental Dermatology University of L\u00fcbeck  L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5926-6407","authenticated-orcid":false,"given":"Renata","family":"Finelli","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Buja","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Unit of Hygiene and Public Health University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola L.","family":"Bragazzi","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Statistics, Laboratory for Industrial and Applied Mathematics (LIAM) York University  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo D. M.","family":"Pigatto","sequence":"additional","affiliation":[{"name":"Clinical Dermatology, IRCCS Istituto Ortopedico Galeazzi  Milan Italy"},{"name":"Department of Biomedical, Surgical, and Dental Sciences University of Milan  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Savoia","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Eastern Piedmont  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13545"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.14376"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13601"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12877"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.09.063"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14346"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14096"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1789044"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19145"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13508"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gloepi.2020.100036"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555563397403"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11081781"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11030601"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11020277"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-017-0183-4"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13626"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.51258"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01167.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.044"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.08.037"},{"key":"e_1_2_8_23_1","first-page":"773","article-title":"Differences of microbiomes found in non\u2010inflammatory and inflammatory lesions of acne vulgaris","volume":"13","author":"Jusuf NK","year":"2020","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-020-00460-1"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13203"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-020-00564-6"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13683"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17093176"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.14848","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dth.14848","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.14848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T14:57:56Z","timestamp":1764169076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.14848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,19]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/dth.14848"],"URL":"https:\/\/doi.org\/10.1111\/dth.14848","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.739483671.793582881","asserted-by":"object"}]},"ISSN":["1396-0296"],"issn-type":[{"value":"1396-0296","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2,19]]},"assertion":[{"value":"2020-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14848"}}