{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T12:57:17Z","timestamp":1774184237760,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T00:00:00Z","timestamp":1634169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012294","name":"National Social Science Fund Youth Project","doi-asserted-by":"publisher","award":["Youth Project"],"award-info":[{"award-number":["Youth Project"]}],"id":[{"id":"10.13039\/501100012294","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012294","name":"National Social Science Fund Youth Project","doi-asserted-by":"publisher","award":["BK20170164"],"award-info":[{"award-number":["BK20170164"]}],"id":[{"id":"10.13039\/501100012294","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nevus of Ota has been successfully treated by lasers. Currently, 1064\u2009nm picosecond Nd:YAG lasers have become available for the treatment of pigmented disorders. However, there are few studies concerning the application of 1064\u2009nm picosecond Nd:YAG laser in nevus of Ota. This study aimed to evaluate the efficacy and safety of a 1064\u2009nm picosecond Nd:YAG laser for the treatment of nevus of Ota. We conducted a retrospective analysis of Chinese patients with nevus of Ota who had been treated with a 1064\u2009nm picosecond Nd:YAG laser. Those who had any other laser treatment during the period of picosecond laser treatment were excluded. Via a visual analog scale for percentage of pigmentary clearance in standard photographs, the treatment efficacy was assessed by three blinded physician evaluators. A total of 16 subjects were included in this retrospective study. The average age at the beginning of treatment was 16.87\u2009years old (range of 4\u00a0months to 59\u2009years), and all patients were of Fitzpatrick skin type IV. Total treatment ranged from 1 to 5 sessions. A 1064\u2009nm picosecond Nd:YAG laser with a mean fluence of 1.8\u20134.3\u00a0J\/cm<jats:sup>2<\/jats:sup> was used at 3\u201312\u2009month intervals. The mean efficacy score for all 16 patients was 2.56 after one session, and the mean efficacy score of 13 patients who completed two sessions and nine patients who completed three sessions were 3.15 and 3.51, respectively. Postinflammatory hyperpigmentation after treatment was only observed in 1 (1\/16, 6.25%) patient. The 1064\u2009nm picosecond Nd:YAG laser is an effective and safe approach for treating nevus of Ota.<\/jats:p>","DOI":"10.1111\/dth.15152","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T02:33:40Z","timestamp":1633574020000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Treatment of nevus of Ota with 1064\u2009nm picosecond Nd:<scp>YAG<\/scp> laser: A retrospective study"],"prefix":"10.1155","volume":"34","author":[{"given":"Hedan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Cosmetic Laser Surgery Institute of Dermatology, Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cosmetic Laser Surgery Institute of Dermatology, Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaorong","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Cosmetic Laser Surgery Institute of Dermatology, Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangdong","family":"Gong","sequence":"additional","affiliation":[{"name":"Division of Sexually Transmitted Disease Epidemiology Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuju","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cosmetic Laser Surgery Institute of Dermatology, Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Nanjing 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