{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:00:13Z","timestamp":1747184413461,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1111\/dth.15662","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T09:10:09Z","timestamp":1655975409000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A study examining the combination of methotrexate and leflunomide with topical anthralin in pediatric alopecia areata\u2014a possible steroid\u2010free regimen with diverse mechanistic actions"],"prefix":"10.1155","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0463-4153","authenticated-orcid":false,"given":"Sinu Rose","family":"Mathachan","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy ABVIMS & Dr. Ram Manohar Lohia Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1757-3406","authenticated-orcid":false,"given":"Kabir","family":"Sardana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy ABVIMS & Dr. Ram Manohar Lohia Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7020-7777","authenticated-orcid":false,"given":"Ananta","family":"Khurana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy ABVIMS & Dr. Ram Manohar Lohia Hospital  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"e_1_2_1_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12913"},{"key":"e_1_2_1_5_3_1","article-title":"Treatment of pediatric alopecia areata: a systematic review","volume":"86","author":"Barton VR","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_1_5_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130078"},{"key":"e_1_2_1_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13688"},{"key":"e_1_2_1_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-019-04669-0"},{"key":"e_1_2_1_5_7_1","first-page":"3079","article-title":"A novel mechanism of action of the immunomodulatory drug, leflunomide: augmentation of the immunosuppressive cytokine, TGF\u2010beta 1, and suppression of the immunostimulatory cytokine, IL\u20102","volume":"28","author":"Cao WW","year":"1996","journal-title":"Transplant Proc"},{"key":"e_1_2_1_5_8_1","doi-asserted-by":"publisher","DOI":"10.1586\/17512433.2015.1019343"},{"key":"e_1_2_1_5_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12178.x"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.15662","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dth.15662","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.15662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T18:04:25Z","timestamp":1671818665000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.15662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,27]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/dth.15662"],"URL":"https:\/\/doi.org\/10.1111\/dth.15662","archive":["Portico"],"relation":{},"ISSN":["1396-0296","1529-8019"],"issn-type":[{"type":"print","value":"1396-0296"},{"type":"electronic","value":"1529-8019"}],"subject":[],"published":{"date-parts":[[2022,7,27]]},"assertion":[{"value":"2022-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}