{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T06:15:19Z","timestamp":1788156919516,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Scabies is a contagious, parasitic skin disease that adversely affects the quality of life and, can cause systemic complications if it is not properly treated. Sulfur ointment and permethrin cream are among the most used topical agents in the treatment of scabies. In this study, we aimed to compare the efficacy of sulfur ointment and permethrin cream in the treatment of scabies. In this single\u2010center study, patients who were diagnosed with scabies in the dermatology outpatient clinics of Karabuk University Training and Research Hospital between April, 2021 and September, 2021 were investigated retrospectively. Age, gender, date of diagnosis, topical agent used for scabies treatment, and response to the treatment at the control examination in the second week were recorded. The patients were divided into two groups those receiving 5% permethrin cream or 10% sulfur ointment, and the treatment efficacy of both agents was compared. This study showed that 10% sulfur ointment was significantly more effective in treating scabies than 5% permethrin cream (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u20090.001). Moreover, younger patients with scabies responded better to both treatments. 10% Sulfur ointment can be considered a safe and effective topical option in the treatment of scabies. The resistance to 5% permethrin cream, which is the most commonly used agent for scabies, can be a concern as an unexpected low success rate was obtained in this study.\n                  <\/jats:p>","DOI":"10.1111\/dth.15897","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T03:04:07Z","timestamp":1664852647000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparison of sulfur ointment and permethrin treatments in scabies"],"prefix":"10.1155","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5167-4780","authenticated-orcid":false,"given":"Goksen","family":"Ertugrul","sequence":"first","affiliation":[{"name":"Department of Dermatology Karabuk University, Faculty of Medicine  Karabuk Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9239-1659","authenticated-orcid":false,"given":"Habibullah","family":"Aktas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Karabuk University, Faculty of Medicine  Karabuk Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.05.109"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2022.02.016"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14351"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000495290"},{"issue":"4","key":"e_1_2_10_6_1","first-page":"427","article-title":"The use of sulfur in dermatology","volume":"3","author":"Gupta AK","year":"2004","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1774489"},{"issue":"11","key":"e_1_2_10_8_1","first-page":"1","article-title":"Comparative efficacy of topical Pertmehrin, Crotamiton and sulfur ointment in treatment of scabies","volume":"14","author":"Mila\u2010Kierzenkowska C","year":"2017","journal-title":"J Arthropod Borne Dis"},{"issue":"2","key":"e_1_2_10_9_1","first-page":"79","article-title":"The efficacy of oral ivermectin vs. sulfur 10% ointment for the treatment of scabies","volume":"61","author":"Alipour H","year":"2015","journal-title":"Ann Parasitol"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2013.12123"},{"issue":"3","key":"e_1_2_10_11_1","first-page":"357","article-title":"Treatment of scabies using 8% and 10% topical sulfur ointment in different regimens of application","volume":"11","author":"Sharquie KE","year":"2012","journal-title":"J Drugs Dermatol"},{"issue":"2","key":"e_1_2_10_12_1","first-page":"230","article-title":"Comparison of efficacy of permethrin 5% cream with Crotamiton 10% cream In patients with scabies","volume":"31","author":"Rao MA","year":"2019","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17339"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.01.004"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13706"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-43"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005920"}],"container-title":["Dermatologic Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.15897","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dth.15897","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dth.15897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:36:16Z","timestamp":1788154576000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dth.15897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,17]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/dth.15897"],"URL":"https:\/\/doi.org\/10.1111\/dth.15897","archive":["Portico"],"relation":{},"ISSN":["1396-0296"],"issn-type":[{"value":"1396-0296","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10,17]]},"assertion":[{"value":"2022-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e15897"}}