{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:40:20Z","timestamp":1791819620767,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T00:00:00Z","timestamp":1667433600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Therapy"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We here report a case of a middle\u2010aged man with an unusual case of bullous lichen sclerosus complicated with generalized morphea. He showed initial recurrent flaccid bullae, followed by ivory\u2010white sclerotic plaques and extensive skin sclerosis, with additional walking disorder caused by knee\u2010joint contracture, and ulcers on the lower extremities and back. The patient had no visceral involvement. After oral hydroxychloroquine and oral corticosteroids failed, the patient was given tofacitinib, which resolved his ulcers after 4\u2009weeks and ameliorated his knee\u2010joint contracture and skin sclerosis within 4\u2009months. Owing to the occurrence of diffuse large B\u2010cell lymphoma, he stopped using tofacitinib, and the ulcer and walking disorder reappeared. This is rare case of bullous lichen sclerosus\u2013generalized morphea overlap syndrome. The patient recovered well after treatment with tofacitinib. His symptoms recurred after discontinuation of tofacitinib.<\/jats:p>","DOI":"10.1111\/dth.15942","type":"journal-article","created":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T04:34:25Z","timestamp":1666067665000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Bullous lichen sclerosus\u2013generalized morphea overlap syndrome improved by tofacitinib"],"prefix":"10.1155","volume":"35","author":[{"given":"Licong","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9208-2087","authenticated-orcid":false,"given":"Yi","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangfan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puyu","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangning","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hainan Provincial Hospital of Skin Disease  Haikou China"},{"name":"Department of Dermatology Affiliated Dermatology Hospital of Hainan Medical College  Haikou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Dermatology Second Xiangya Hospital of Central South University  Changsha China"},{"name":"Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.06.037"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12724"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.04.003"},{"issue":"11","key":"e_1_2_10_5_1","first-page":"1545","article-title":"The anti\u2010fibrotic effect of cold atmospheric plasma on localized scleroderma In vitro and In 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