{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:11:36Z","timestamp":1790701896405,"version":"4.1.0"},"reference-count":77,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,2,7]],"date-time":"2016-02-07T00:00:00Z","timestamp":1454803200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,2,7]],"date-time":"2016-02-07T00:00:00Z","timestamp":1454803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Cancer Care"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1111\/ecc.12446","type":"journal-article","created":{"date-parts":[[2016,2,8]],"date-time":"2016-02-08T03:23:55Z","timestamp":1454901835000},"page":"e12446","source":"Crossref","is-referenced-by-count":54,"title":["Tumour-associated antigens and their anti-cancer applications"],"prefix":"10.1155","volume":"26","author":[{"given":"C.-C.","family":"Liu","sequence":"first","affiliation":[{"name":"Translational Medicine Center; Hong-Hui Hospital; Xi'an Jiaotong University College of Medicine; Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Yang","sequence":"additional","affiliation":[{"name":"Translational Medicine Center; Hong-Hui Hospital; Xi'an Jiaotong University College of Medicine; Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Translational Medicine Center; Hong-Hui Hospital; Xi'an Jiaotong University College of Medicine; Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-J.","family":"Zhao","sequence":"additional","affiliation":[{"name":"Translational Medicine Center; Hong-Hui Hospital; Xi'an Jiaotong University College of Medicine; Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.-J.","family":"Hao","sequence":"additional","affiliation":[{"name":"Spine Surgery; Hong-Hui Hospital; Xi'an Jiaotong University College of Medicine; Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,7]]},"reference":[{"key":"10.1111\/ecc.12446-BIB0001|ecc12446-cit-0001","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1002\/ijc.27727","article-title":"Preoperative serum tissue polypeptide-specific antigen is a valuable prognostic marker in breast cancer","volume":"132","author":"Ahn","year":"2013","journal-title":"International Journal of Cancer"},{"key":"10.1111\/ecc.12446-BIB0002|ecc12446-cit-0002","first-page":"3905","article-title":"Analysis of MUC4 expression in human pancreatic cancer xenografts in immunodeficient mice","volume":"34","author":"Ansari","year":"2014","journal-title":"Anticancer Research"},{"key":"10.1111\/ecc.12446-BIB0003|ecc12446-cit-0003","doi-asserted-by":"crossref","first-page":"6396","DOI":"10.1158\/1078-0432.CCR-07-1036","article-title":"A contemporary prognostic nomogram for men with hormone-refractory metastatic prostate cancer: a TAX327 study analysis","volume":"13","author":"Armstrong","year":"2007","journal-title":"Clinical Cancer Research"},{"key":"10.1111\/ecc.12446-BIB0004|ecc12446-cit-0004","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s13000-015-0266-4","article-title":"Expression of glypican 3 in low and high grade urothelial carcinomas","volume":"10","author":"Aydin","year":"2015","journal-title":"Diagnostic Pathology"},{"key":"10.1111\/ecc.12446-BIB0005|ecc12446-cit-0005","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1007\/s13277-013-1033-3","article-title":"Biomarkers for pancreatic cancer: promising new markers and options beyond CA 19-9","volume":"34","author":"Ballehaninna","year":"2013","journal-title":"Tumour Biology"},{"key":"10.1111\/ecc.12446-BIB0006|ecc12446-cit-0006","doi-asserted-by":"crossref","first-page":"8409","DOI":"10.7314\/APJCP.2014.15.19.8409","article-title":"Clinical applicability of multi-tumor marker protein chips for diagnosing ovarian cancer","volume":"15","author":"Bian","year":"2014","journal-title":"Asian Pacific Journal of Cancer Prevention"},{"key":"10.1111\/ecc.12446-BIB0007|ecc12446-cit-0007","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1158\/1541-7786.MCR-15-0234","article-title":"Maximizing the therapeutic potential of Hsp90 inhibitors","volume":"13","author":"Butler","year":"2015","journal-title":"Molecular Cancer Research"},{"key":"10.1111\/ecc.12446-BIB0008|ecc12446-cit-0008","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1023\/A:1025815113599","article-title":"Mucins and mucin binding proteins in colorectal cancer","volume":"23","author":"Byrd","year":"2004","journal-title":"Cancer and Metastasis Reviews"},{"key":"10.1111\/ecc.12446-BIB0009|ecc12446-cit-0009","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1177\/1756287213495915","article-title":"Biomarkers in prostate cancer surveillance and screening: past, present, and future","volume":"5","author":"Cary","year":"2013","journal-title":"Therapeutic Advances in Urology"},{"key":"10.1111\/ecc.12446-BIB0010|ecc12446-cit-0010","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/ajcp\/101.4.465","article-title":"Breast cancer marker Ca549. A multicenter study","volume":"101","author":"Chan","year":"1994","journal-title":"American Journal of Clinical Pathology"},{"key":"10.1111\/ecc.12446-BIB0012|ecc12446-cit-0012","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1186\/1471-2407-13-539","article-title":"Systematic review and meta-analysis of tumor biomarkers in predicting prognosis in esophageal cancer","volume":"13","author":"Chen","year":"2013","journal-title":"BMC Cancer"},{"key":"10.1111\/ecc.12446-BIB0013|ecc12446-cit-0013","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.biopha.2007.08.005","article-title":"Potentially useful biomarkers for the diagnosis, treatment and prognosis of lung cancer","volume":"61","author":"Cho","year":"2007","journal-title":"Biomedicine and Pharmacotherapy"},{"key":"10.1111\/ecc.12446-BIB0014|ecc12446-cit-0014","first-page":"135","article-title":"New biomarkers in prostate cancer","volume":"28","author":"Crawford","year":"2014","journal-title":"Oncology (Williston Park)"},{"key":"10.1111\/ecc.12446-BIB0015|ecc12446-cit-0015","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1172\/JCI200113712","article-title":"Glypicans: proteoglycans with a surprise","volume":"108","author":"Filmus","year":"2001","journal-title":"Journal of Clinical Investigation"},{"key":"10.1111\/ecc.12446-BIB0016|ecc12446-cit-0016","doi-asserted-by":"crossref","first-page":"6536","DOI":"10.1038\/ncomms7536","article-title":"Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis","volume":"6","author":"Gao","year":"2015","journal-title":"Nature Communications"},{"key":"10.1111\/ecc.12446-BIB0017|ecc12446-cit-0017","doi-asserted-by":"crossref","first-page":"216","DOI":"10.5301\/jbm.5000001","article-title":"Saliva CA125 and TPS levels in patients with oral squamous cell carcinoma","volume":"28","author":"Geng","year":"2013","journal-title":"International Journal of Biological Markers"},{"key":"10.1111\/ecc.12446-BIB0018|ecc12446-cit-0018","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3748\/wjg.15.1301","article-title":"Diagnosis of hepatocellular carcinoma","volume":"15","author":"Gomaa","year":"2009","journal-title":"World Journal of Gastroenterology"},{"key":"10.1111\/ecc.12446-BIB0019|ecc12446-cit-0019","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s10620-008-0371-2","article-title":"Serum levels of keratin-18 fragments [tissue polypeptide-specific antigen (TPS)] are correlated with hepatocyte apoptosis in alcoholic hepatitis","volume":"54","author":"Gonzalez-Quintela","year":"2009","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1111\/ecc.12446-BIB0020|ecc12446-cit-0020","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.lungcan.2011.11.012","article-title":"Carcinoembryonic antigen (CEA) as tumor marker in lung cancer","volume":"76","author":"Grunnet","year":"2012","journal-title":"Lung Cancer"},{"key":"10.1111\/ecc.12446-BIB0021|ecc12446-cit-0021","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1136\/jcp.2007.051383","article-title":"Squamous cell carcinoma antigen in human liver carcinogenesis","volume":"61","author":"Guido","year":"2008","journal-title":"Journal of Clinical Pathology"},{"key":"10.1111\/ecc.12446-BIB0022|ecc12446-cit-0022","doi-asserted-by":"crossref","first-page":"e114506","DOI":"10.1371\/journal.pone.0114506","article-title":"Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells","volume":"9","author":"Haggerty","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1111\/ecc.12446-BIB0023|ecc12446-cit-0023","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1021\/acs.molpharmaceut.5b00132","article-title":"Glypican-3 targeted human heavy chain antibody as a drug carrier for hepatocellular carcinoma therapy","volume":"12","author":"Hanaoka","year":"2015","journal-title":"Molecular Pharmaceutics"},{"key":"10.1111\/ecc.12446-BIB0024|ecc12446-cit-0024","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s40259-014-0114-1","article-title":"Peptide-based vaccination and induction of CD8+ T-cell responses against tumor antigens in breast cancer","volume":"29","author":"Harao","year":"2015","journal-title":"BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy"},{"key":"10.1111\/ecc.12446-BIB0025|ecc12446-cit-0025","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.3892\/or.2012.1935","article-title":"Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model","volume":"28","author":"Hayashi","year":"2012","journal-title":"Oncology Reports"},{"key":"10.1111\/ecc.12446-BIB0500|ecc12446-cit-0500","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1471-230X-13-87","article-title":"Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer","volume":"13","author":"He","year":"2013","journal-title":"BMC Gastroenterol"},{"key":"10.1111\/ecc.12446-BIB0026|ecc12446-cit-0026","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.2174\/0929867311320220001","article-title":"Targeting heat shock proteins in prostate cancer","volume":"20","author":"Hessenkemper","year":"2013","journal-title":"Current Medicinal Chemistry"},{"key":"10.1111\/ecc.12446-BIB0027|ecc12446-cit-0027","doi-asserted-by":"crossref","first-page":"287","DOI":"10.7150\/jca.10819","article-title":"Complementary roles of squamous cell carcinoma antigen and (18)F-FDG PET\/CT in suspected recurrence of cervical squamous cell cancer","volume":"6","author":"Hu","year":"2015","journal-title":"Journal of Cancer"},{"key":"10.1111\/ecc.12446-BIB0028|ecc12446-cit-0028","doi-asserted-by":"crossref","first-page":"170","DOI":"10.5306\/wjco.v5.i2.170","article-title":"Prognostic value of preoperative serum tumor markers in gastric cancer","volume":"5","author":"Huang","year":"2014","journal-title":"World Journal of Clinical Oncology"},{"key":"10.1111\/ecc.12446-BIB0029|ecc12446-cit-0029","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/nrurol.2013.108","article-title":"The role of heat shock proteins in bladder cancer","volume":"10","author":"Ischia","year":"2013","journal-title":"Nature Reviews Urology"},{"key":"10.1111\/ecc.12446-BIB0030|ecc12446-cit-0030","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/MOU.0b013e32835e9f1a","article-title":"The promise of heat shock protein inhibitors in the treatment of castration resistant prostate cancer","volume":"23","author":"Ischia","year":"2013","journal-title":"Current Opinion in Urology"},{"key":"10.1111\/ecc.12446-BIB0031|ecc12446-cit-0031","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3322\/caac.20073","article-title":"Cancer statistics, 2010","volume":"60","author":"Jemal","year":"2010","journal-title":"CA - A Cancer Journal for Clinicians"},{"key":"10.1111\/ecc.12446-BIB0032|ecc12446-cit-0032","doi-asserted-by":"crossref","first-page":"7272","DOI":"10.18632\/oncotarget.2370","article-title":"Altered mucins (MUC) trafficking in benign and malignant conditions","volume":"5","author":"Joshi","year":"2014","journal-title":"Oncotarget"},{"key":"10.1111\/ecc.12446-BIB0033|ecc12446-cit-0033","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1385\/MO:20:2:157","article-title":"Expression of heat shock protein (Hsp) 70 and Hsp 40 in colorectal cancer","volume":"20","author":"Kanazawa","year":"2003","journal-title":"Medical Oncology"},{"key":"10.1111\/ecc.12446-BIB0034|ecc12446-cit-0034","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3389\/fgene.2014.00346","article-title":"Heat shock protein 27 phosphorylation state is associated with cancer progression","volume":"5","author":"Katsogiannou","year":"2014","journal-title":"Frontiers in Genetics"},{"key":"10.1111\/ecc.12446-BIB0035|ecc12446-cit-0035","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3346\/jkms.2015.30.3.259","article-title":"Postoperative carcinoembryonic antigen as a complementary tumor marker of carbohydrate antigen 19-9 in pancreatic ductal adenocarcinoma","volume":"30","author":"Kim","year":"2015","journal-title":"Journal of Korean Medical Science"},{"key":"10.1111\/ecc.12446-BIB0036|ecc12446-cit-0036","doi-asserted-by":"crossref","first-page":"10547","DOI":"10.1007\/s13277-014-2355-5","article-title":"Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer","volume":"35","author":"Lai","year":"2014","journal-title":"Tumor Biology"},{"key":"10.1111\/ecc.12446-BIB0037|ecc12446-cit-0037","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.bios.2015.07.049","article-title":"Highly sensitive electrochemical immunosensor for the detection of alpha fetoprotein based on PdNi nanoparticles and N-doped graphene nanoribbons","volume":"74","author":"Li","year":"2015a","journal-title":"Biosensors and Bioelectr onics"},{"key":"10.1111\/ecc.12446-BIB0038|ecc12446-cit-0038","doi-asserted-by":"crossref","first-page":"e0122361","DOI":"10.1371\/journal.pone.0122361","article-title":"The predictive value of serum squamous cell carcinoma antigen in patients with cervical cancer who receive neoadjuvant chemotherapy followed by radical surgery: a single-institute study","volume":"10","author":"Li","year":"2015b","journal-title":"PLoS ONE"},{"key":"10.1111\/ecc.12446-BIB0039|ecc12446-cit-0039","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1477-7819-10-68","article-title":"Prognostic significance of tumor markers in T4a gastric cancer","volume":"10","author":"Liu","year":"2012","journal-title":"World Journal of Surgical Oncology"},{"key":"10.1111\/ecc.12446-BIB0040|ecc12446-cit-0040","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.arcmed.2015.03.003","article-title":"Overexpression of squamous cell carcinoma antigen 1 is associated with the onset and progression of human hepatocellular carcinoma","volume":"46","author":"Liu","year":"2015","journal-title":"Archives of Medical Research"},{"key":"10.1111\/ecc.12446-BIB0041|ecc12446-cit-0041","first-page":"715","article-title":"Tumor makers in cervical cancer","volume":"78","author":"Markowska","year":"2007","journal-title":"Ginekologia Polska"},{"key":"10.1111\/ecc.12446-BIB0042|ecc12446-cit-0042","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.bmcl.2013.02.014","article-title":"Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets","volume":"23","author":"Mcconnell","year":"2013","journal-title":"Bioorganic and Medicinal Chemistry Letters"},{"key":"10.1111\/ecc.12446-BIB0043|ecc12446-cit-0043","doi-asserted-by":"crossref","first-page":"31","DOI":"10.7150\/jca.7987","article-title":"Current approaches and challenges for monitoring treatment response in colon and rectal cancer","volume":"5","author":"Mckeown","year":"2014","journal-title":"Journal of Cancer"},{"key":"10.1111\/ecc.12446-BIB0044|ecc12446-cit-0044","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/1471-2296-13-100","article-title":"Prostate specific antigen testing policy worldwide varies greatly and seems not to be in accordance with guidelines: a systematic review","volume":"13","author":"Meer","year":"2012","journal-title":"BMC Family Practice"},{"key":"10.1111\/ecc.12446-BIB0045|ecc12446-cit-0045","first-page":"42","article-title":"The prognostic role of tumor marker CA-125 in B-cell non-Hodgkin's lymphoma","volume":"8","author":"Memar","year":"2015","journal-title":"Iranian Journal of Cancer Prevention"},{"key":"10.1111\/ecc.12446-BIB0046|ecc12446-cit-0046","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2165\/00063030-200519020-00001","article-title":"Usefulness of the novel oncofetal antigen glypican-3 for diagnosis of hepatocellular carcinoma and melanoma","volume":"19","author":"Nakatsura","year":"2005","journal-title":"BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy"},{"key":"10.1111\/ecc.12446-BIB0047|ecc12446-cit-0047","first-page":"1193","article-title":"Molecular genetic tumor markers in non-small cell lung cancer","volume":"25","author":"Oyama","year":"2005","journal-title":"Anticancer Research"},{"key":"10.1111\/ecc.12446-BIB0048|ecc12446-cit-0048","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1177\/039463200802100302","article-title":"Strategies to overcome obstacles to successful immunotherapy of melanoma","volume":"21","author":"Pandolfi","year":"2008","journal-title":"International Journal of Immunopathology and Pharmacology"},{"key":"10.1111\/ecc.12446-BIB0049|ecc12446-cit-0049","first-page":"128","article-title":"Usefulness of evaluation of soluble fragment cytokeratin 18, carcinoembryonic antigen and gastrointestinal carcinoma-associated antigen in diagnostic of patients with colorectal cancer","volume":"29","author":"Partyka","year":"2010","journal-title":"Polski Merkuriusz Lekarski"},{"key":"10.1111\/ecc.12446-BIB0050|ecc12446-cit-0050","doi-asserted-by":"crossref","first-page":"497478","DOI":"10.1155\/2014\/497478","article-title":"Utility of preoperative CA125 assay in the management planning of women diagnosed with uterine cancer","volume":"2014","author":"Povolotskaya","year":"2014","journal-title":"Surgery Research and Practice"},{"key":"10.1111\/ecc.12446-BIB0051|ecc12446-cit-0051","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.bpg.2014.07.018","article-title":"Hepatocellular carcinoma tumour markers: current role and expectations","volume":"28","author":"Rich","year":"2014","journal-title":"Best Practice and Research in Clinical Gastroenterology"},{"key":"10.1111\/ecc.12446-BIB0052|ecc12446-cit-0052","doi-asserted-by":"crossref","first-page":"587","DOI":"10.2217\/bmm.12.72","article-title":"Biomarkers for the diagnosis of new and recurrent prostate cancer","volume":"6","author":"Sardana","year":"2012","journal-title":"Biomarkers in Medicine"},{"issue":"Suppl. 1","key":"10.1111\/ecc.12446-BIB0053|ecc12446-cit-0053","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3109\/0284186X.2010.542174","article-title":"Tumor markers in prostate cancer I: blood-based markers","volume":"50","author":"Shariat","year":"2011","journal-title":"Acta Oncologica"},{"key":"10.1111\/ecc.12446-BIB0054|ecc12446-cit-0054","doi-asserted-by":"crossref","first-page":"2918","DOI":"10.1200\/JCO.2005.01.529","article-title":"Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer","volume":"23","author":"Smith","year":"2005","journal-title":"Journal of Clinical Oncology"},{"key":"10.1111\/ecc.12446-BIB0055|ecc12446-cit-0055","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000346220","article-title":"Biomarkers: evaluation of screening for and early diagnosis of hepatocellular carcinoma in Japan and china","volume":"2","author":"Song","year":"2013","journal-title":"Liver Cancer"},{"key":"10.1111\/ecc.12446-BIB0056|ecc12446-cit-0056","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3748\/wjg.v16.i4.418","article-title":"Present and future possibilities for early diagnosis of hepatocellular carcinoma","volume":"16","author":"Stefaniuk","year":"2010","journal-title":"World Journal of Gastroenterology"},{"key":"10.1111\/ecc.12446-BIB0057|ecc12446-cit-0057","first-page":"99","article-title":"Prostate-specific antigen and other serum and urine markers in prostate cancer","volume":"1846","author":"Stephan","year":"2014","journal-title":"Biochimica et Biophysica Acta-bioenergetics"},{"key":"10.1111\/ecc.12446-BIB0058|ecc12446-cit-0058","doi-asserted-by":"crossref","first-page":"8699","DOI":"10.1073\/pnas.1017909109","article-title":"Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer","volume":"109","author":"Straume","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1111\/ecc.12446-BIB0059|ecc12446-cit-0059","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1186\/1477-7819-12-397","article-title":"Clinical evaluation of CEA, CA19-9, CA72-4 and CA125 in gastric cancer patients with neoadjuvant chemotherapy","volume":"12","author":"Sun","year":"2014","journal-title":"World Journal of Surgical Oncology"},{"key":"10.1111\/ecc.12446-BIB0060|ecc12446-cit-0060","first-page":"1","article-title":"The diagnostics of colorectal cancer","volume":"18","author":"Swiderska","year":"2014","journal-title":"Contemporary Oncology (Pozn)"},{"key":"10.1111\/ecc.12446-BIB0061|ecc12446-cit-0061","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.4161\/21645515.2014.973317","article-title":"Antigen-specific vaccines for cancer treatment","volume":"10","author":"Tagliamonte","year":"2014","journal-title":"Human Vaccines and\u00a0Immunotherapeutics"},{"key":"10.1111\/ecc.12446-BIB0062|ecc12446-cit-0062","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1365-2362.2007.01745.x","article-title":"Serum concentrations of the tissue polypeptide specific antigen in patients suffering from non-alcoholic steatohepatitis","volume":"37","author":"Tarantino","year":"2007","journal-title":"European Journal of Clinical Investigation"},{"key":"10.1111\/ecc.12446-BIB0063|ecc12446-cit-0063","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s12072-007-9038-x","article-title":"Diagnostic accuracy of tumor markers for hepatocellular carcinoma: a systematic review","volume":"2","author":"Tateishi","year":"2008","journal-title":"Hepatology International"},{"key":"10.1111\/ecc.12446-BIB0064|ecc12446-cit-0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.07.049","article-title":"Improved detection of hepatocellular carcinoma using a longitudinal alpha-fetoprotein screening algorithm","author":"Tayob","year":"2015","journal-title":"Clinical Gastroenterology and Hepatology"},{"key":"10.1111\/ecc.12446-BIB0065|ecc12446-cit-0065","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1159\/000030045","article-title":"SCC antigen in malignant and nonmalignant squamous lesions","volume":"19","author":"Torre","year":"1998","journal-title":"Tumor Biology"},{"key":"10.1111\/ecc.12446-BIB0066|ecc12446-cit-0066","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.2174\/13816128112092472","article-title":"Mucin-based targeted pancreatic cancer therapy","volume":"18","author":"Torres","year":"2012","journal-title":"Current Pharmaceutical Design"},{"key":"10.1111\/ecc.12446-BIB0067|ecc12446-cit-0067","doi-asserted-by":"crossref","first-page":"865","DOI":"10.5306\/wjco.v5.i5.865","article-title":"Tumour suppressor HLJ1: a potential diagnostic, preventive and therapeutic target in non-small cell lung cancer","volume":"5","author":"Tsai","year":"2014","journal-title":"World Journal of Clinical Oncology"},{"key":"10.1111\/ecc.12446-BIB0068|ecc12446-cit-0068","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2174\/157489212801820020","article-title":"Carcinoembryonic antigen (CEA)-based cancer vaccines: recent patents and antitumor effects from experimental models to clinical trials","volume":"7","author":"Turriziani","year":"2012","journal-title":"Recent Patents on Anti-Cancer Drug Discovery"},{"key":"10.1111\/ecc.12446-BIB0069|ecc12446-cit-0069","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1499-3872(15)60396-4","article-title":"Glypican-3 is a biomarker and a therapeutic target of hepatocellular carcinoma","volume":"14","author":"Wang","year":"2015","journal-title":"Hepatobiliary and Pancreatic Diseases International"},{"key":"10.1111\/ecc.12446-BIB0070|ecc12446-cit-0070","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1443-9573.2006.00263.x","article-title":"Evaluation of the diagnostic value of serum tumor markers, and fecal k-ras and p53 gene mutations for pancreatic cancer","volume":"7","author":"Wu","year":"2006","journal-title":"Chinese Journal of Digestive Diseases"},{"key":"10.1111\/ecc.12446-BIB0071|ecc12446-cit-0071","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.4161\/hv.29836","article-title":"Tecemotide: an antigen-specific cancer immunotherapy","volume":"10","author":"Wurz","year":"2014","journal-title":"Human Vaccines and Immunotherapeutics"},{"key":"10.1111\/ecc.12446-BIB0072|ecc12446-cit-0072","first-page":"1513","article-title":"L-BLP25 as a peptide vaccine therapy in non-small cell lung cancer: a review","volume":"6","author":"Xia","year":"2014","journal-title":"Journal of Thoracic Disease"},{"key":"10.1111\/ecc.12446-BIB0073|ecc12446-cit-0073","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s00534-009-0174-7","article-title":"Significance of mucin expression in pancreatobiliary neoplasms","volume":"17","author":"Yonezawa","year":"2010","journal-title":"Journal of Hepato-Biliary-Pancreatic Sciences"},{"key":"10.1111\/ecc.12446-BIB0074|ecc12446-cit-0074","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1440-1827.2011.02734.x","article-title":"Mucins in human neoplasms: clinical pathology, gene expression and diagnostic application","volume":"61","author":"Yonezawa","year":"2011","journal-title":"Pathology International"},{"key":"10.1111\/ecc.12446-BIB0075|ecc12446-cit-0075","doi-asserted-by":"crossref","first-page":"9367","DOI":"10.7314\/APJCP.2014.15.21.9367","article-title":"Prediction of lung cancer based on serum biomarkers by gene expression programming methods","volume":"15","author":"Yu","year":"2014","journal-title":"Asian Pacific Journal of Cancer Prevention"},{"key":"10.1111\/ecc.12446-BIB0076|ecc12446-cit-0076","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1158\/1078-0432.CCR-06-2090","article-title":"Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity","volume":"13","author":"Zhang","year":"2007","journal-title":"Clinical Cancer Research"},{"key":"10.1111\/ecc.12446-BIB0077|ecc12446-cit-0077","doi-asserted-by":"crossref","first-page":"19225","DOI":"10.3390\/s150819225","article-title":"Simultaneous detection of alpha-fetoprotein and carcinoembryonic antigen based on Si nanowire field-effect transistors","volume":"15","author":"Zhu","year":"2015","journal-title":"Sensors (Basel)"}],"container-title":["European Journal of Cancer Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecc.12446","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecc.12446","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ecc.12446\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:10:03Z","timestamp":1671541803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ecc.12446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,7]]},"references-count":77,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"URL":"https:\/\/doi.org\/10.1111\/ecc.12446","archive":["Portico"],"relation":{},"ISSN":["0961-5423"],"issn-type":[{"value":"0961-5423","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2,7]]}}}