{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:27:01Z","timestamp":1765758421603,"version":"3.37.3"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T00:00:00Z","timestamp":1455062400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T00:00:00Z","timestamp":1455062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Cancer Care"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1111\/ecc.12452","type":"journal-article","created":{"date-parts":[[2016,2,10]],"date-time":"2016-02-10T12:43:10Z","timestamp":1455108190000},"page":"e12452","source":"Crossref","is-referenced-by-count":14,"title":["Health resource utilisation associated with skeletal-related events in patients with bone metastases secondary to solid tumours: regional comparisons in an observational study"],"prefix":"10.1155","volume":"26","author":[{"given":"I.","family":"Duran","sequence":"first","affiliation":[{"name":"Medical Oncology Department; Centro Integral Oncologico Clara Campal; Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.G.","family":"Fink","sequence":"additional","affiliation":[{"name":"Orange Coast Memorial Medical Center; Fountain Valley CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bahl","sequence":"additional","affiliation":[{"name":"Bristol Haematology and Oncology Centre; University Hospitals Bristol; Bristol UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hoefeler","sequence":"additional","affiliation":[{"name":"Forschungszentrum Ruhr; KliFoCenter GmbH; Witten Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mahmood","sequence":"additional","affiliation":[{"name":"Cancer Specialists of South Texas; Corpus Christi Cancer Center; Corpus Christi TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"L\u00fcftner","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin Berlin; Charit\u00e9 Campus Benjamin Franklin; Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Ghazal","sequence":"additional","affiliation":[{"name":"Kentucky Cancer Clinic; Hazard KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Wei","sequence":"additional","affiliation":[{"name":"Biostatistics; Amgen, Inc.; Thousand Oaks CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.C.","family":"Chung","sequence":"additional","affiliation":[{"name":"Global Health Economics; Amgen Inc.; Thousand Oaks CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Hechmati","sequence":"additional","affiliation":[{"name":"Global Health Economics; Amgen Inc.; Zug Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Green","sequence":"additional","affiliation":[{"name":"Global Study Management; Amgen Inc.; Thousand Oaks CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Atchison","sequence":"additional","affiliation":[{"name":"Global Health Economics; Amgen Inc.; Thousand Oaks CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,10]]},"reference":[{"key":"10.1111\/ecc.12452-BIB0001|ecc12452-cit-0001","doi-asserted-by":"crossref","first-page":"693","DOI":"10.18553\/jmcp.2010.16.9.693","article-title":"Payer costs for inpatient treatment of pathologic fracture, surgery to bone, and spinal cord compression among patients with multiple myeloma or bone metastasis secondary to prostate or breast cancer","volume":"16","author":"Barlev","year":"2010","journal-title":"Journal of Managed Care Pharmacy"},{"key":"10.1111\/ecc.12452-BIB0002|ecc12452-cit-0002","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0167-8140(99)00097-3","article-title":"8\u00a0Gy single fraction radiotherapy for the treatment of metastatic skeletal pain: randomised comparison with a multifraction schedule over 12\u00a0months of patient follow-up. Bone Pain Trial Working Party","volume":"52","author":"Bone Pain Trial Working Party","year":"1999","journal-title":"Radiotherapy and Oncology"},{"key":"10.1111\/ecc.12452-BIB0003|ecc12452-cit-0003","unstructured":"Breast 2013 National Comprehensive Cancer Center Clinical Practice Guidelines in Oncology: Breast Cancer http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/breast.pdf"},{"key":"10.1111\/ecc.12452-BIB0004|ecc12452-cit-0004","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1053\/hp.2000.6698","article-title":"Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients","volume":"31","author":"Bubendorf","year":"2000","journal-title":"Human Pathology"},{"issue":"Suppl. 7","key":"10.1111\/ecc.12452-BIB0005|ecc12452-cit-0005","doi-asserted-by":"crossref","first-page":"vii11","DOI":"10.1093\/annonc\/mds232","article-title":"Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"23","author":"Cardoso","year":"2012","journal-title":"Annals of Oncology"},{"key":"10.1111\/ecc.12452-BIB0006|ecc12452-cit-0006","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1191\/0269216305pm1079oa","article-title":"Painful bone metastases: a prospective observational cohort study","volume":"19","author":"Clare","year":"2005","journal-title":"Palliative Medicine"},{"key":"10.1111\/ecc.12452-BIB0007|ecc12452-cit-0007","doi-asserted-by":"crossref","first-page":"6243s","DOI":"10.1158\/1078-0432.CCR-06-0931","article-title":"Clinical features of metastatic bone disease and risk of skeletal morbidity","volume":"12","author":"Coleman","year":"2006","journal-title":"Clinical Cancer Research"},{"key":"10.1111\/ecc.12452-BIB0008|ecc12452-cit-0008","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00520-008-0418-0","article-title":"Impact of skeletal complications on patients\u2019 quality of life, mobility, and functional independence","volume":"16","author":"Costa","year":"2008","journal-title":"Supportive Care in Cancer"},{"key":"10.1111\/ecc.12452-BIB0009|ecc12452-cit-0009","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1159\/000082923","article-title":"The cost of treatment of skeletal-related events in patients with bone metastases from lung cancer","volume":"67","author":"Delea","year":"2004","journal-title":"Oncology"},{"key":"10.1111\/ecc.12452-BIB0010|ecc12452-cit-0010","first-page":"341","article-title":"Retrospective study of the effect of skeletal complications on total medical care costs in patients with bone metastases of breast cancer seen in typical clinical practice","volume":"4","author":"Delea","year":"2006","journal-title":"Journal of Supportive Oncology"},{"key":"10.1111\/ecc.12452-BIB0011|ecc12452-cit-0011","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s00520-006-0203-x","article-title":"Effects of skeletal morbidities on longitudinal patient-reported outcomes and survival in patients with metastatic prostate cancer","volume":"15","author":"Depuy","year":"2007","journal-title":"Supportive Care in Cancer"},{"key":"10.1111\/ecc.12452-BIB0012|ecc12452-cit-0012","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s12094-013-1077-2","article-title":"Cost analysis of skeletal-related events in Spanish patients with bone metastases from solid tumours","volume":"16","author":"Duran","year":"2014","journal-title":"Clinical and Translational Oncology"},{"key":"10.1111\/ecc.12452-BIB0014|ecc12452-cit-0014","unstructured":"EuroQol www.euroqol.org"},{"key":"10.1111\/ecc.12452-BIB0015|ecc12452-cit-0015","doi-asserted-by":"crossref","first-page":"691","DOI":"10.3111\/13696998.2013.779921","article-title":"Cost of skeletal-related events in European patients with solid tumours and bone metastases: data from a prospective multinational observational study","volume":"16","author":"Hechmati","year":"2013","journal-title":"Journal of Medical Economics"},{"key":"10.1111\/ecc.12452-BIB0016|ecc12452-cit-0016","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jbo.2014.04.001","article-title":"Health resource utilization associated with skeletal-related events in patients\u00a0with bone metastases: Results from a multinational retrospective - prospective observational study - a cohort from 4 European countries","volume":"3","author":"Hoefeler","year":"2014","journal-title":"Journal of Bone Oncology"},{"issue":"Suppl. 5","key":"10.1111\/ecc.12452-BIB0017|ecc12452-cit-0017","doi-asserted-by":"crossref","first-page":"v129","DOI":"10.1093\/annonc\/mdq174","article-title":"Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"21","author":"Horwich","year":"2010","journal-title":"Annals of Oncology"},{"key":"10.1111\/ecc.12452-BIB0018|ecc12452-cit-0018","first-page":"317","article-title":"The cost of treating skeletal-related events in patients with prostate cancer","volume":"14","author":"Lage","year":"2008","journal-title":"The American Journal of Managed Care"},{"key":"10.1111\/ecc.12452-BIB0019|ecc12452-cit-0019","first-page":"205","article-title":"Pathophysiology of bone metastases: how this knowledge may lead to therapeutic intervention","volume":"2","author":"Lipton","year":"2004","journal-title":"Journal of Supportive Oncology"},{"key":"10.1111\/ecc.12452-BIB0020|ecc12452-cit-0020","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.ijrobp.2010.11.026","article-title":"Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline","volume":"79","author":"Lutz","year":"2011","journal-title":"International Journal of Radiation Oncology Biology Physics"},{"key":"10.1111\/ecc.12452-BIB0021|ecc12452-cit-0021","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.cmonc.2012.02.015","article-title":"Health-resource utilization attributable to skeletal-related events in patients with advanced cancers associated with bone metastases: results of the US cohort from a multicenter observational study","volume":"9","author":"Mahmood","year":"2012","journal-title":"Community Oncology"},{"key":"10.1111\/ecc.12452-BIB0022|ecc12452-cit-0022","unstructured":"NSCLC 2013 National Comprehensive Cancer Center Clinical Practice Guidelines in Oncology: Non small cell lung cancer http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/nscl.pdf"},{"issue":"Suppl. 7","key":"10.1111\/ecc.12452-BIB0023|ecc12452-cit-0023","doi-asserted-by":"crossref","first-page":"vii56","DOI":"10.1093\/annonc\/mds226","article-title":"Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"23","author":"Peters","year":"2012","journal-title":"Annals of Oncology"},{"key":"10.1111\/ecc.12452-BIB0024|ecc12452-cit-0024","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/j.1365-2354.2009.01135.x","article-title":"The hospital burden of disease associated with bone metastases and skeletal-related events in patients with breast cancer, lung cancer, or prostate cancer in Spain","volume":"19","author":"Pockett","year":"2010","journal-title":"European Journal of Cancer Care (England)"},{"key":"10.1111\/ecc.12452-BIB0025|ecc12452-cit-0025","unstructured":"Prostate 2013 National Comprehensive Cancer Center Clinical Practice Guidelines in Oncology: Prostate Cancer http:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/prostate.pdf"},{"key":"10.1111\/ecc.12452-BIB0026|ecc12452-cit-0026","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/pcan.2011.7","article-title":"Mortality following bone metastasis and skeletal-related events among men with prostate cancer: a population-based analysis of US Medicare beneficiaries, 1999-2006","volume":"14","author":"Sathiakumar","year":"2011","journal-title":"Prostate Cancer and Prostatic Diseases"},{"key":"10.1111\/ecc.12452-BIB0027|ecc12452-cit-0027","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s10549-011-1721-x","article-title":"Mortality following bone metastasis and skeletal-related events among women with breast cancer: a population-based analysis of U.S. Medicare beneficiaries, 1999-2006","volume":"131","author":"Sathiakumar","year":"2012","journal-title":"Breast Cancer Research and Treatment"},{"key":"10.1111\/ecc.12452-BIB0028|ecc12452-cit-0028","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0167-8140(99)00110-3","article-title":"The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study","volume":"52","author":"Steenland","year":"1999","journal-title":"Radiotherapy and Oncology"},{"key":"10.1111\/ecc.12452-BIB0029|ecc12452-cit-0029","doi-asserted-by":"crossref","first-page":"712","DOI":"10.3111\/13696998.2012.675380","article-title":"Cost-effectiveness of denosumab vs zoledronic acid for prevention of skeletal-related events in patients with solid tumors and bone metastases in the United States","volume":"15","author":"Stopeck","year":"2012","journal-title":"Journal of Medical Economics"},{"key":"10.1111\/ecc.12452-BIB0013|ecc12452-cit-0013","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol - a new facility for the measurement of health-related quality of life","volume":"16","author":"The EuroQol Group","year":"1990","journal-title":"Health Policy"},{"key":"10.1111\/ecc.12452-BIB0030|ecc12452-cit-0030","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/annonc\/mdi122","article-title":"The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer","volume":"16","author":"Weinfurt","year":"2005","journal-title":"Annals of Oncology"}],"container-title":["European Journal of Cancer Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecc.12452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecc.12452","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ecc.12452\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:10:19Z","timestamp":1671541819000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ecc.12452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,10]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"URL":"https:\/\/doi.org\/10.1111\/ecc.12452","archive":["Portico"],"relation":{},"ISSN":["0961-5423"],"issn-type":[{"type":"print","value":"0961-5423"}],"subject":[],"published":{"date-parts":[[2016,2,10]]}}}