{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:08:10Z","timestamp":1760249290175},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T00:00:00Z","timestamp":1357862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Decreased right ventricular (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) ejection fraction (<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>) increases morbidity in repaired tetralogy of <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>allot (r<jats:styled-content style=\"fixed-case\">ToF<\/jats:styled-content>). Cardiac magnetic resonance (<jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content>) is the accepted reference standard for <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> measurement. There are no established color <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>oppler tissue imaging (c<jats:styled-content style=\"fixed-case\">DTI<\/jats:styled-content>) values that identify decreased <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> in r<jats:styled-content style=\"fixed-case\">ToF<\/jats:styled-content>. We sought to assess accuracy of c<jats:styled-content style=\"fixed-case\">DTI<\/jats:styled-content> myocardial deformation and velocity indices in predicting <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content>\u2010derived <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective evaluation of <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content> and echocardiography studies performed on the same day. c<jats:styled-content style=\"fixed-case\">DTI<\/jats:styled-content>\u2010derived peak systolic velocity (pkS), isovolumic acceleration (<jats:styled-content style=\"fixed-case\">IVA<\/jats:styled-content>) of the tricuspid valve annulus, strain (\u03b5) and strain rate (<jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>) of the <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> free wall, adjusted for age, volume and pressure overload were used to compute <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content>. The probability of correctly classifying <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content> measured <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> &lt;45% was estimated by logistic regression analysis. The accuracy of the model was tested on 10 prospective patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty matched echocardiographic and <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content> studies were analyzed. None of the individual c<jats:styled-content style=\"fixed-case\">DTI<\/jats:styled-content> parameters could reliably identify patients with <jats:styled-content style=\"fixed-case\">CMR<\/jats:styled-content>\u2010derived decreased <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content>. However, when adjusted for age in a logistic model: Y\u00a0=\u00a0\u22120.5 \u2212\u00a00.07\u00a0\u00d7\u00a0age\u00a0+ 0.016\u00a0\u00d7\u00a0\u03b5\u00a0+\u00a00.46\u00a0\u00d7\u00a0pkS, where Y is the logit (log odds), patients with <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> &lt;45% were identified with 86% sensitivity, 93.5% specificity. Prospective application of this model correctly identified all subjects with <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> &lt;45%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The age\u2010adjusted logistic model and not individual parameters, derived from c<jats:styled-content style=\"fixed-case\">DTI<\/jats:styled-content>\u2010derived pkS, and \u03b5 can reliably identify patients with decreased <jats:styled-content style=\"fixed-case\">RV EF<\/jats:styled-content> &lt;45%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12103","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T09:59:21Z","timestamp":1357898361000},"page":"196-202","source":"Crossref","is-referenced-by-count":8,"title":["Echocardiographic Myocardial Deformation Evaluation of Right Ventricular Function in Comparison with <scp>CMRI<\/scp> in Repaired Tetralogy of <scp>F<\/scp>allot: A Cross\u2010Sectional and Longitudinal Validation Study"],"prefix":"10.1111","volume":"30","author":[{"given":"Shubhika","family":"Srivastava","sequence":"first","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yishay","family":"Salem","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samprit","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Helen Ko","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wyman W.","family":"Lai","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira A.","family":"Parness","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene D.","family":"Lytrivi","sequence":"additional","affiliation":[{"name":"Mount Sinai Medical Center New York New 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