{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:40:35Z","timestamp":1791906035364,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Diabetes accelerates the natural process of atherosclerosis and is a predictor for progression of atherosclerotic lesions. To improve clinical outcomes, noninvasive imaging modalities have been proposed to measure and monitor atherosclerosis. Recently, it has been shown that the color M\u2010mode\u2013derived propagation velocity of the descending thoracic aorta (aortic velocity propagation [<jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content>]) was associated with coronary and carotid atherosclerosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Carotid intima\u2010media thickness (<jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> were measured in 72 patients with newly diagnosed type 2 diabetes and 44 healthy people. Individuals who had previously used oral hypoglycemic agents or insulin treatment or had a history of hyperlipidemia, cigarette smoking, hypertension, and cardiovascular disease were excluded from this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared with control group, patients with type 2 diabetes had significantly lower <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> (39.9\u00a0\u00b1\u00a06.5 vs. 58.4\u00a0\u00b1\u00a06.7\u00a0cm\/sec, P\u00a0&lt;\u00a00.001) and higher <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> (1.1\u00a0\u00b1\u00a00.1 vs. 0.95\u00a0\u00b1\u00a00.12\u00a0mm, P\u00a0&lt;\u00a00.001) measurements. There were significant correlations between <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> (r\u00a0=\u00a0\u22120.835, P\u00a0&lt;\u00a00.001), <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> and fasting plasma glucose (r\u00a0=\u00a0\u22120.796, P\u00a0<jats:italic>&lt;<\/jats:italic>\u00a00.001)), <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> and HbA1 c (r\u00a0=\u00a0\u22120918 P\u00a0<jats:italic>&lt;<\/jats:italic>\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Diabetes mellitus may be associated with subclinical atherosclerosis assessed by measurement of <jats:styled-content style=\"fixed-case\">AVP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>. These simple methods might improve patient selection for primary prevention atherosclerotic progression.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12125","type":"journal-article","created":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T17:33:17Z","timestamp":1359048797000},"page":"644-648","source":"Crossref","is-referenced-by-count":11,"title":["A Novel Echocardiographic Method for the Detection of Subclinical Atherosclerosis in Newly Diagnosed, Untreated Type 2 Diabetes"],"prefix":"10.1111","volume":"30","author":[{"given":"Hakki","family":"Simsek","sequence":"first","affiliation":[{"name":"Cardiology Department Yuzunci Yil University Faculty of Medicine Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa","family":"Sahin","sequence":"additional","affiliation":[{"name":"Cardiology Department Yuzunci Yil University Faculty of Medicine Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilmaz","family":"Gunes","sequence":"additional","affiliation":[{"name":"Cardiology Department Hisar Intercontinental Hospital Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Dogan","sequence":"additional","affiliation":[{"name":"Cardiology Department Dumlupinar University Faculty of Medicine Kutahya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan Ali","family":"Gumrukcuoglu","sequence":"additional","affiliation":[{"name":"Cardiology Department Yuzunci Yil University Faculty of Medicine Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Tuncer","sequence":"additional","affiliation":[{"name":"Cardiology Department Yuzunci Yil University Faculty of Medicine Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,24]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"586","volume-title":"Manuel of Cardiovascular Medicine","author":"Eric J. 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