{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T06:08:21Z","timestamp":1760249301045},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,2,22]],"date-time":"2013-02-22T00:00:00Z","timestamp":1361491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate echocardiographic changes after <jats:styled-content style=\"fixed-case\">SAPIEN<\/jats:styled-content> valve implantation in the pulmonary position.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>The feasibility of the <jats:styled-content style=\"fixed-case\">SAPIEN<\/jats:styled-content> transcatheter pulmonary valve (<jats:styled-content style=\"fixed-case\">TPV<\/jats:styled-content>) has recently been demonstrated. We evaluated changes in pulmonary valve function and the right ventricle after <jats:styled-content style=\"fixed-case\">SAPIEN TPV<\/jats:styled-content> placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated echocardiograms at baseline, discharge, 1 and 6\u00a0months after <jats:styled-content style=\"fixed-case\">TPV<\/jats:styled-content> placement in 33 patients from 4 centers. Pulmonary insufficiency severity was graded 0\u20134. <jats:styled-content style=\"fixed-case\">TPV<\/jats:styled-content> peak and mean gradients were measured. Right ventricular (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) size and function were quantified using routine measures derived from color, spectral, and tissue Doppler indices and two\u2010dimensional echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, 94% patients demonstrated pulmonary insufficiency grade 2\u20134. This decreased to 12% patients at 6\u00a0months (P\u00a0&lt;\u00a00.01). <jats:styled-content style=\"fixed-case\">TPV<\/jats:styled-content> peak (P\u00a0&lt;\u00a00.01) and mean gradient (P\u00a0&lt;\u00a00.01) decreased. <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> end\u2010diastolic area indexed to body surface area (BSA) (P\u00a0&lt;\u00a00.01), Tricuspid regurgitation (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>) gradient (P\u00a0&lt;\u00a00.01), and the ratio of <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> jet area to BSA (P\u00a0&lt;\u00a00.01) decreased. Tricuspid inflow peak E:A, tissue Doppler imaging (<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>): septal E' and A', <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>: tricuspid A' improved between baseline and discharge, but trended back to baseline by 6\u2010month follow\u2010up. Tricuspid valve annulus <jats:italic>z<\/jats:italic>\u2010score, <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> area change, tricuspid annular plane systolic excursion (<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>), <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> dP\/dt, tricuspid E:E', and <jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>: tricuspid annulus E' showed no change.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Improvements in pulmonary insufficiency and stenosis, <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> size, and <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content> gradient and severity are seen after <jats:styled-content style=\"fixed-case\">SAPIEN TPV<\/jats:styled-content> placement. Selected indices of <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> diastolic function improve immediately after <jats:styled-content style=\"fixed-case\">TPV<\/jats:styled-content> implantation, but return to baseline by 6\u00a0months. <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> systolic function is unchanged.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12147","type":"journal-article","created":{"date-parts":[[2013,2,22]],"date-time":"2013-02-22T08:01:42Z","timestamp":1361520102000},"page":"786-793","source":"Crossref","is-referenced-by-count":12,"title":["Early Echocardiographic Changes After Percutaneous Implantation of the Edwards <scp>SAPIEN<\/scp> Transcatheter Heart Valve in the Pulmonary Position"],"prefix":"10.1111","volume":"30","author":[{"given":"Shahryar M.","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Pediatrics Medical University of South Carolina Charleston South 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