{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:49:05Z","timestamp":1790668145914,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T00:00:00Z","timestamp":1375833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,1]]},"abstract":"\n Objective<\/jats:title>\n \n The aim of this study was to evaluate the impact of left ventricular diastolic dysfunction on predicting postoperative pulmonary edema and major cardiovascular events (\n MACE<\/jats:styled-content>\n ) in patients who underwent low\u2010 or intermediate\u2010risk noncardiac surgery.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A total of 692 patients aged >60\u00a0years who underwent transthoracic echocardiography (\n TTE<\/jats:styled-content>\n ) before undergoing elective low\u2010 or intermediate\u2010risk noncardiac surgery were prospectively enrolled. The medical history and\n TTE<\/jats:styled-content>\n variables were assessed. Each patient was clinically evaluated for postoperative pulmonary edema and\n MACE<\/jats:styled-content>\n . The presence of postoperative pulmonary edema and\n MACE<\/jats:styled-content>\n were evaluated during a 30\u2010day follow\u2010up period after surgery.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We identified 166 patients with pulmonary edema and 49 patients with\n MACE<\/jats:styled-content>\n . After adjusting for clinical and\n TTE<\/jats:styled-content>\n variables, multivariate analysis demonstrated that a ratio of early transmitral flow velocity to early diastolic velocity of the mitral annulus (\n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032) >15, pulmonary artery systolic pressure (\n PASP<\/jats:styled-content>\n ) \u226535\u00a0mmHg, and left ventricular hypertrophy (\n LVH<\/jats:styled-content>\n ) were significantly associated with postoperative pulmonary edema (\n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032, P\u00a0<\u00a00.001:\n PASP<\/jats:styled-content>\n , P\u00a0=\u00a00.005;\n LVH<\/jats:styled-content>\n , P\u00a0=\u00a00.017). The multivariate analysis for\n MACE<\/jats:styled-content>\n after adjusting for clinical risk factors indicated that\n MACE<\/jats:styled-content>\n were significantly associated with an\n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032\u00a0>\u00a015 (P\u00a0<\u00a00.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032\u00a0>\u00a015,\n PASP<\/jats:styled-content>\n elevation, and\n LVH<\/jats:styled-content>\n on preoperative\n TTE<\/jats:styled-content>\n predicted postoperative pulmonary edema, and\n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032\u00a0>\u00a015 predicted\n MACE<\/jats:styled-content>\n in the patients who underwent low\u2010 or intermediate\u2010risk noncardiac surgery. Thus, we believe that clinicians need to be cautious when providing perioperative care to patients with high\n E<\/jats:italic>\n \/\n e<\/jats:italic>\n \u2032 ratios who are indicated for\n TTE<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.12285","type":"journal-article","created":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T05:17:39Z","timestamp":1375852659000},"page":"42-49","source":"Crossref","is-referenced-by-count":51,"title":["Presence of Preoperative Diastolic Dysfunction Predicts Postoperative Pulmonary Edema and Cardiovascular Complications in Patients Undergoing Noncardiac Surgery"],"prefix":"10.1111","volume":"31","author":[{"given":"Dong\u2010Hyuk","family":"Cho","sequence":"first","affiliation":[{"name":"Division of Cardiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong\u2010Mi","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Cardiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi\u2010Na","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su\u2010A","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HaeJa","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Anesthesiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan\u2010Joo","family":"Shim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Korea University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,8,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01421-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00144-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.15.1788"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.066423"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3182426ed6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192690"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp337"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-011-0195-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep005"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(89)80014-8"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep007"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.12.032"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000083527.45070.F2"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181da89ca"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000127882.58426.7A"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.12.017"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00909-8"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.12285","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.12285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T23:19:05Z","timestamp":1696288745000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.12285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,7]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/echo.12285"],"URL":"https:\/\/doi.org\/10.1111\/echo.12285","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,7]]}}}