{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:20:58Z","timestamp":1778584858939,"version":"3.51.4"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T00:00:00Z","timestamp":1379548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Right ventricular (RV) dysfunction is a well\u2010recognized complication of cardiopulmonary bypass surgery (CPB) in adults. Infants and neonates may also be at high risk for this due to immature myocardium. Conventional assessment of RV function is just qualitative, but novel tissue Doppler echocardiographic (TDI) markers including peak systolic strain rate (SR) and isovolumic contraction acceleration (IVA) permit noninvasive quantitation of RV function. This study assessed myocardial velocities, IVA and SR in infants and neonates undergoing open heart surgery using TDI to study regional myocardial function perioperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Transthoracic TDI data were obtained in the OR before and 24\u00a0hours post\u2010CPB on 53 consecutive infants (age 0.39\u00a0\u00b1\u00a00.23\u00a0years). They were followed with TDI through hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean CPB time was 87\u00a0\u00b1\u00a049\u00a0min (cross\u2010clamp 52\u00a0\u00b1\u00a026\u00a0min). Peak systolic (S<jats:sub>TDI<\/jats:sub>) and diastolic myocardial velocities (E<jats:sub>TDI<\/jats:sub>, A<jats:sub>TDI<\/jats:sub>), IVA, and peak SR were recorded in RV and LV from standard views for offline analysis. Postoperatively, LV systolic function and diastolic longitudinal function were unchanged or improved from baseline. LV radial velocities were increased postoperatively indicating adequate support. In contrast, RV longitudinal systolic and diastolic function was significantly diminished after CPB. RV changes persisted through hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In infants and neonates, perioperative measurements of systolic and diastolic tissue Doppler parameters are feasible and revealed significant RV systolic and diastolic dysfunction post\u2010CPB with preserved LV function. As such, TDI provides a sensitive tool to monitor the infant heart after CPB and may potentially be useful to assess different myocardial protection strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12347","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T16:30:51Z","timestamp":1381249851000},"page":"209-217","source":"Crossref","is-referenced-by-count":10,"title":["Right Ventricular Wall\u2010Motion Changes after Infant Open Heart Surgery\u2014A Tissue Doppler Study"],"prefix":"10.1111","volume":"31","author":[{"given":"Linda B.","family":"Pauliks","sequence":"first","affiliation":[{"name":"Pediatric Cardiology Penn State Hershey Medical College Hershey Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilliam M.","family":"Valdes\u2010Cruz","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Joe DiMaggio Children's Hospital Hollywood Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Perryman","sequence":"additional","affiliation":[{"name":"Pediatric Cardiovascular Surgery Joe DiMaggio Children's Hospital Hollywood Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank G.","family":"Scholl","sequence":"additional","affiliation":[{"name":"Pediatric Cardiovascular Surgery Joe DiMaggio Children's Hospital Hollywood Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0022-5223(19)39159-7","article-title":"Selective right ventricular dysfunction after coronary artery bypass grafting","volume":"86","author":"Rabinovitch MA","year":"1983","journal-title":"J Thorac Cardiovasc 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