{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:07:12Z","timestamp":1760015232056},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Right heart evaluation on coronary computed tomography angiography (<jats:styled-content style=\"fixed-case\">CCTA<\/jats:styled-content>) is underutilized due to nonopacification of the right heart chambers and poor endocardial resolution. We analyzed feasibility and reproducibility of right heart functional analysis by measuring <jats:styled-content style=\"fixed-case\">CCTA<\/jats:styled-content>\u2010based tricuspid annular plane systolic excursion (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>) on <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content>\u2010gated <jats:styled-content style=\"fixed-case\">CCTA<\/jats:styled-content> and correlated the results with 2D transthoracic echocardiography (<jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content>)\u2010derived <jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> (Echo\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> was measured on a total population of 41 patients who had <jats:styled-content style=\"fixed-case\">CCTA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> performed within 6\u00a0months of each other. Two independent <jats:styled-content style=\"fixed-case\">CCTA<\/jats:styled-content> readers performed analysis on reformatted four\u2010chamber view. Intra\u2010 and inter\u2010observer variability analysis was performed on 16 randomly selected patients. Correlative (Spearman's R) and Bland\u2013Altman analysis was used to assess the level of agreement between the 2 methods and to compare <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> with Echo\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> measured by Readers 1 and 2 on 16 randomly selected patients, demonstrated excellent intra\u2010observer and inter\u2010observer agreement, with very close correlation (R\u00a0&gt;\u00a00.80 and 2\u2010tailed P\u2010value of &lt;0.001). When tested in the entire study population of 41 patients, <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> correlated closely with Echo\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> (R\u00a0=\u00a00.738, P\u00a0&lt;\u00a00.001). Bland\u2013Altman analysis indicated that the 2 methods provided similar measures as majority of values lay within the 95% confidence limits. Based on abnormal Echo\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> cutoff value of &lt;16\u00a0mm, <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> identified impaired right ventricle (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) function with sensitivity of 82% and specificity of 93%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We demonstrated feasibility and reproducibility of assessing <jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> on coronary <jats:styled-content style=\"fixed-case\">CTA<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> functional analysis utilizing <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> is simple and reproducible methodology, and is in close agreement with Echo\u2010<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12461","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T16:11:21Z","timestamp":1390579881000},"page":"773-778","source":"Crossref","is-referenced-by-count":7,"title":["Coronary Computed Tomography Angiography\u2010Based Tricuspid Annular Plane Systolic Excursion: Correlation with 2D Echocardiography"],"prefix":"10.1111","volume":"31","author":[{"given":"Jaspreet","family":"Singh","sequence":"first","affiliation":[{"name":"Division of Cardiology The University of Arizona College of Medicine Tucson Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Borgstrom","sequence":"additional","affiliation":[{"name":"Division of Cardiology The University of Arizona College of Medicine Tucson 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