{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T23:29:19Z","timestamp":1748993359080},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T00:00:00Z","timestamp":1395705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Right ventricular (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) deformational mechanics have been demonstrated in patients with atrial septal defect (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>) at rest, but there is lack of information on their adaptation to exercise. The aim of this study was to assess the adaptability of <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> strains and strain rates (SRs) during exercise in patients with clinically asymptomatic <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty patients with asymptomatic <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> and 11 age\u2010matched controls were included. All the subjects performed incremental ergometry and underwent standard echocardiography and two\u2010dimensional strain (S) and SR imaging by speckle tracking at rest and during submaximal exercise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference in <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> strains and SRs at rest between the controls and the <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> patients. There was a significant elevation in the strains and SRs of both groups with exercise. However, the lateral and septal strains increased significantly higher than the controls in patients with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>. But there was no significant difference in SRs during exercise in both of the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Asymptomatic <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> patients without <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> overload, have same strain and SR results at rest with the controls, however, these findings worsen during submaximal exercise, when compared to the controls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12570","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T07:49:41Z","timestamp":1395733781000},"page":"1239-1244","source":"Crossref","is-referenced-by-count":6,"title":["Strain Analysis during Exercise in Patients with Asymptomatic Atrial Septal Defect"],"prefix":"10.1111","volume":"31","author":[{"given":"Onur","family":"Baydar","sequence":"first","affiliation":[{"name":"Department of Cardiology Mus State Hospital Mus Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veysel","family":"Oktay","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kahta State Hospital Kahta Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umit Yasar","family":"Sinan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Viransehir State Hospital Viransehir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinem","family":"Cakal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mus State Hospital Mus Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beytullah","family":"Cakal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Mus State Hospital Mus Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugur","family":"Coskun","sequence":"additional","affiliation":[{"name":"Department of Cardiology Institute of Cardiology Istanbul 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