{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T05:09:41Z","timestamp":1723093781975},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T00:00:00Z","timestamp":1395705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,11]]},"abstract":"Background<\/jats:title>Severe mitral stenosis (MS<\/jats:styled-content>) may impair left atrial (LA<\/jats:styled-content>) pump function, and increase LA<\/jats:styled-content> and pulmonary venous pressure resulting in right ventricular (RV<\/jats:styled-content>) systolic dysfunction. The aim of this study was to evaluate biventricular and LA<\/jats:styled-content> function after percutaneous mitral balloon valvuloplasty (PMBV<\/jats:styled-content>) by tissue Doppler (TDI<\/jats:styled-content>) and speckle\u00a0tracking echocardiography (STE<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Twenty\u2010eight consecutive patients with severe symptomatic rheumatic MS<\/jats:styled-content> (11 men, mean age: 39\u00a0\u00b1\u00a07\u00a0years) who were referred for PMBV<\/jats:styled-content> were included in the study. In addition to conventional echocardiography, all patients underwent TDI<\/jats:styled-content> and two\u2010dimensional (2D) (STE<\/jats:styled-content>) to assess left ventricular (LV<\/jats:styled-content>), LA<\/jats:styled-content>, and RV<\/jats:styled-content> function before and 3\u00a0months after PMBV<\/jats:styled-content>. Severity of mitral regurgitation (MR<\/jats:styled-content>) was graded by the ratio of MR<\/jats:styled-content> jet area to LA<\/jats:styled-content> area (JA<\/jats:styled-content>\/LAA<\/jats:styled-content>) method and any postprocedural progression of the JA<\/jats:styled-content>\/LAA<\/jats:styled-content> ratio was defined as worsening of MR<\/jats:styled-content>. Peak systolic velocity of tricuspid lateral annulus (RV<\/jats:styled-content>s) <11.5\u00a0cm\/sec was accepted as RV<\/jats:styled-content> dysfunction.<\/jats:p><\/jats:sec>Results<\/jats:title>Left atrial diameter and area were decreased, while LV<\/jats:styled-content> dimensions were unchanged following the valvuloplasty. PMBV<\/jats:styled-content> improved STE<\/jats:styled-content>\u2010based LV<\/jats:styled-content> mechanical indices, LA<\/jats:styled-content> reservoir and conduit function, and RV<\/jats:styled-content> free wall basal longitudinal strain (LS) and displacement. Increased severity of MR<\/jats:styled-content> was detected in 6 patients, and PMBV<\/jats:styled-content> did not improve the STE<\/jats:styled-content>\u2010based RV<\/jats:styled-content> or LV<\/jats:styled-content> function in these patients, while LA<\/jats:styled-content> reservoir and conduit function were both improved independent of MR<\/jats:styled-content> worsening. There was significant improvement in RV<\/jats:styled-content>s and RV<\/jats:styled-content> basal LS in the 15 patients with preprocedural RV<\/jats:styled-content> systolic dysfunction, while the improvement in patients with normal preprocedural RV<\/jats:styled-content> function was not significant.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Percutaneous mitral balloon valvuloplasty may improve both LA<\/jats:styled-content> and biventricular function in patients with severe symptomatic MS<\/jats:styled-content>. Both TDI<\/jats:styled-content> and STE<\/jats:styled-content> are useful to determine biventricular and LA<\/jats:styled-content> function after PMBV<\/jats:styled-content>. Although the number of patients was insufficient, worsening of MR<\/jats:styled-content> after PMBV<\/jats:styled-content> may limit the improvement in RV<\/jats:styled-content> and LV<\/jats:styled-content> function, while preprocedural RV<\/jats:styled-content> dysfunction does not seem to limit the improvement in RV<\/jats:styled-content> function and pulmonary artery systolic pressure. Large scale follow\u2010up studies are required to see whether the changes observed in cardiac mechanics are persistent.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12580","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T06:39:07Z","timestamp":1395729547000},"page":"1213-1220","source":"Crossref","is-referenced-by-count":11,"title":["Effect of Increased Severity of Mitral Regurgitation and Preprocedural Right Ventricular Systolic Dysfunction on Biventricular and Left Atrial Mechanical Functions Following Percutaneous Mitral Balloon Valvuloplasty"],"prefix":"10.1111","volume":"31","author":[{"given":"Kursat","family":"Tigen","sequence":"first","affiliation":[{"name":"Department of Cardiology Marmara University Faculty of Medicine Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selcuk","family":"Pala","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Heart Training and Research 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