{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:05:24Z","timestamp":1789556724411,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T00:00:00Z","timestamp":1410393600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To describe the echocardiographic findings detected as first manifestations of Beh\u00e7et's disease (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>) and compare these findings with those detected in established cases of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> receiving regular medical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two groups of patients were studied. Group 1 comprised 41 patients with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> on regular medical treatment. Group 2 comprised 5 previously healthy patients who presented to the cardiology department because of cardiac symptoms and were diagnosed in retrospect during hospitalization as <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>. Thirty\u2010two age\u2010 and sex\u2010matched individuals served as control subjects (control group). All patients and controls underwent complete M\u2010mode, two\u2010dimensional, and Doppler transthoracic echocardiographic examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 41 treated patients with <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> (mean age: 32\u00a0\u00b1\u00a08\u00a0years, 90% males, mean duration since diagnosis: 14.5\u00a0years), only 1 patient was found to have severe aortic regurgitation secondary to aortic root dilation. On the other hand, the 5 previously healthy patients who presented with cardiac symptoms (mean age: 24\u00a0\u00b1\u00a06\u00a0years, all males) had significant cardiac involvement and evident echocardiographic findings (P\u00a0&lt;\u00a00.001). Four cases had intracardiac masses: 3 in the right atrium (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>), 1 in the right ventricle (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>), while the last patient had pericardial effusion (<jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content>). All these patients were diagnosed in retrospect as <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> masses disappeared on medical therapy, while the <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> mass was surgically excised and proved to be multiple thrombi histopathologically. The patient with <jats:styled-content style=\"fixed-case\">PE<\/jats:styled-content> had recurrent attacks of massive effusion so a pericardial window was performed surgically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Diagnosis of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> might be initially suspected by the cardiologists based on certain echocardiographic findings, namely the presence of right\u2010sided masses. Diagnosis of <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content> in such patients has important therapeutic implications and accordingly prognostic value.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12601","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T11:56:37Z","timestamp":1410436597000},"page":"924-930","source":"Crossref","is-referenced-by-count":10,"title":["Value of Certain Echocardiographic Findings in the Initial Suspicion of Beh\u00e7et's Disease"],"prefix":"10.1111","volume":"31","author":[{"given":"Heba","family":"Farouk","sequence":"first","affiliation":[{"name":"Cardiovascular Medicine Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim El","family":"Chilali","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Said","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basma","family":"Sakr","sequence":"additional","affiliation":[{"name":"Rheumatology Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hania","family":"Salah","sequence":"additional","affiliation":[{"name":"Rheumatology Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geilan","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Rheumatology Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Sorour","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine Department Cairo University Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,11]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1152","article-title":"\u00dcber rezidivierende, Apht\u00f6se, durch ein Virus verursachte Geschw\u00fcre am Mund, am Auge und an den Genitalien","volume":"105","author":"Beh\u00e7et H","year":"1937","journal-title":"Dermatol Wochenschr"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(91)90060-3"},{"key":"e_1_2_7_4_1","first-page":"109","article-title":"[Arterial manifestations of Behcet's disease. 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