{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:06:09Z","timestamp":1762506369330},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T00:00:00Z","timestamp":1404518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The prognostic value of stress echocardiography (<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>) in patients with complete bundle branch blocks (<jats:styled-content style=\"fixed-case\">BBB<\/jats:styled-content>) with normal left ventricular ejection fraction (<jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content>) has not been well described. We sought to determine the prognostic value of <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> in patients with <jats:styled-content style=\"fixed-case\">BBB<\/jats:styled-content> and normal <jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed 7214 patients (58\u00a0\u00b1\u00a014\u00a0years; 57% female) with a mean follow\u2010up time of 9\u00a0\u00b1\u00a04\u00a0years. Dobutamine <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> was performed in 51% of patients and exercise <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> was performed in 49%. All\u2010cause mortality data were obtained from the Social Security Death Index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 222 (3%) patients with right bundle branch block (<jats:styled-content style=\"fixed-case\">RBBB<\/jats:styled-content>) and 50 (0.7%) patients with left bundle branch block (<jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content>). Patients with <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> were 3 times more likely to have an abnormal stress test after adjusting for age, gender, mode of stress test, and coronary artery disease risk factors (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a03.3; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.86\u20135.92; P\u00a0&lt;\u00a00.001). The mortality rates were 4.5%\/year for patients with <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content>, 2.5%\/year for patients with <jats:styled-content style=\"fixed-case\">RBBB<\/jats:styled-content>, and 1.9%\/year for patients without <jats:styled-content style=\"fixed-case\">BBB<\/jats:styled-content> (P\u00a0&lt;\u00a00.001). Among patients with a normal <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>, those with <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> had similar mortality to those without <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a00.9; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.4\u20132.2; P\u00a0=\u00a00.8). Patients with <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> and abnormal <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> had more than 2 times greater risk of all\u2010cause mortality (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a02.4; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.4\u20134.2; P\u00a0=\u00a00.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A normal stress echocardiogram in <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> is associated with benign prognosis while those with <jats:styled-content style=\"fixed-case\">LBBB<\/jats:styled-content> and abnormal <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content> have the worst outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12680","type":"journal-article","created":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T07:03:28Z","timestamp":1404543808000},"page":"483-489","source":"Crossref","is-referenced-by-count":16,"title":["Prevalence and Long\u2010Term Prognosis of Patients with Complete Bundle Branch Block (Right or Left Bundle Branch) with Normal Left Ventricular Ejection Fraction Referred for Stress Echocardiography"],"prefix":"10.1111","volume":"32","author":[{"given":"Azhar A.","family":"Supariwala","sequence":"first","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Ricardo F.","family":"Po","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameh","family":"Mohareb","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhan","family":"Aslam","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firas","family":"Kaddaha","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zainab I.","family":"Mian","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhan","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Otokiti","sequence":"additional","affiliation":[{"name":"Mount Sinai St. Luke's and Roosevelt Icahn School of Medicine at Mount Sinai New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farooq A.","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital Icahn School of Medicine at Mount Sinai New York New 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