{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:48:41Z","timestamp":1791910121536,"version":"4.3.4"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T00:00:00Z","timestamp":1405987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5T32HL07710"],"award-info":[{"award-number":["5T32HL07710"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with free pulmonary regurgitation or mixed pulmonary stenosis and regurgitation and severely dilated right ventricles (RV) show little improvement in ventricular function after pulmonary valve replacement when assessed by traditional echocardiographic markers. We evaluated changes in right and left ventricular (LV) function using speckle tracking echocardiography in patients after SAPIEN transcatheter pulmonary valve (TPV) placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Echocardiograms were evaluated at baseline, discharge, 1 and 6\u00a0months after TPV placement in 24 patients from 4 centers. Speckle\u00a0tracking measures of function included peak longitudinal strain, strain rate, and early diastolic strain rate. RV fractional area change, tricuspid annular plane systolic excursion, and left ventricular LV ejection fraction were assessed. Routine Doppler and tissue Doppler velocities were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At baseline, all patients demonstrated moderate to severe pulmonary regurgitation; this improved following TPV placement. No significant changes were detected in conventional measures of RV or LV function at 6\u00a0months. RV longitudinal strain (\u221216.9% vs. \u221219.6%, P\u00a0&lt;\u00a00.01), strain rate (\u22120.87 s<jats:sup>\u22121<\/jats:sup> vs. \u22121.16 s<jats:sup>\u22121<\/jats:sup>, P\u00a0=\u00a00.01), and LV longitudinal strain (\u221216.2% vs. \u221218.2%, P\u00a0=\u00a00.01) improved between baseline and 6\u00a0month follow\u2010up. RV early diastolic strain rate, LV longitudinal strain rate and early diastolic strain rate showed no change.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Improvements in RV longitudinal strain, strain rate, and LV longitudinal strain are seen at 6\u00a0months post\u2010TPV. Diastolic function does not appear to change at 6\u00a0months. Speckle\u00a0tracking echocardiography may be more sensitive than traditional measures in detecting changes in systolic function after TPV implantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12700","type":"journal-article","created":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T10:24:30Z","timestamp":1406024670000},"page":"461-469","source":"Crossref","is-referenced-by-count":10,"title":["Changes in Speckle\u00a0Tracking Echocardiography Measures of Ventricular Function after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position"],"prefix":"10.1111","volume":"32","author":[{"given":"Shahryar M.","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Pediatrics Medical University of South Carolina Charleston South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyad M.","family":"Hijazi","sequence":"additional","affiliation":[{"name":"Rush Center for Congenital &amp; Structural Heart Disease Rush University Medical Center Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Duke University Medical Center Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saibal","family":"Kar","sequence":"additional","affiliation":[{"name":"Department of Medicine Cedar Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Makkar","sequence":"additional","affiliation":[{"name":"Department of Medicine Cedar Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mullen","sequence":"additional","affiliation":[{"name":"Department of Medicine The Heart Hospital London United 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