{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T03:06:11Z","timestamp":1763867171173},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T00:00:00Z","timestamp":1405987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) is the most common sustained arrhythmia, with a high recurrence rate, especially during the first months after cardioversion (<jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>). Few parameters have been evaluated as predictors for the maintenance of sinus rhythm (<jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>), with limited results. Recently total atrial conduction time (<jats:styled-content style=\"fixed-case\">TACT<\/jats:styled-content>) has been proposed as independent predictor of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence. The aim of this study was to investigate the prognostic value of <jats:styled-content style=\"fixed-case\">TACT<\/jats:styled-content>, measured using <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content> duration, to predict 1\u2010year maintenance of restored <jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content> after electrical <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>In a population of 104 patients (58 male, aged 70\u00a0\u00b1\u00a09) with persistent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>, submitted to external electrical <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>, we performed a complete echocardiogram after restoring <jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">TACT<\/jats:styled-content> was estimated by measuring the time delay between the onset of the P\u2010wave in lead II of the surface electrocardiogram and the peak A\u2032\u2010wave on the tissue Doppler imaging (TDI) tracing of the left atrial lateral wall (so\u2010called <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content> duration). After a mean follow\u2010up of 14\u00a0\u00b1\u00a02\u00a0months, 34 (33%) patients had recurrent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>, whereas 70 (67%) patients maintained <jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>. At multivariate analysis only <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content> was identified as independent predictor of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.04; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20131.06; P\u00a0&lt;\u00a00.001). Receiver operator characteristics curve analyses demonstrated a high degree of discrimination (area under the curve 0.923); with a cut point of 152\u00a0msec, we obtain a good diagnostic accuracy (sensitivity 91%, specificity 87%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">TACT<\/jats:styled-content> using TDI is an independent predictor of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence and can be used to predict the maintenance of <jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content> after external electrical <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12702","type":"journal-article","created":{"date-parts":[[2014,7,22]],"date-time":"2014-07-22T10:23:58Z","timestamp":1406024638000},"page":"420-427","source":"Crossref","is-referenced-by-count":14,"title":["Prognostic Value of Total Atrial 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