{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:52:46Z","timestamp":1788580366396,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T00:00:00Z","timestamp":1412640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,5]]},"abstract":"Background<\/jats:title>Right ventricular (RV<\/jats:styled-content>) function is reduced in infants with pulmonary hypertension (PH<\/jats:styled-content>) but echocardiographic assessment can be challenging. We sought to determine the role of tricuspid annular plane systolic excursion (TAPSE<\/jats:styled-content>) in infants with PH<\/jats:styled-content> and compared it with other markers such as tricuspid annular S' and RV<\/jats:styled-content> fractional area change (RVFAC<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Retrospective review of medical records of 30 infants treated for PH<\/jats:styled-content> and 69 healthy controls from January 2012 to November 2012 was performed. Patients with significant congenital heart disease were excluded. Offline analysis of echocardiograms was performed to obtain TAPSE<\/jats:styled-content>, tricuspid annular S', and RVFAC<\/jats:styled-content>. TAPSE<\/jats:styled-content> was indexed to body surface area (TAPSE<\/jats:styled-content>\/BSA<\/jats:styled-content>). Logistic regression analysis was performed to evaluate the relation between echocardiographic markers and PH<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>TAPSE<\/jats:styled-content> and TAPSE<\/jats:styled-content>\/BSA<\/jats:styled-content> were significantly lower in PH<\/jats:styled-content> patients. PH<\/jats:styled-content> patients were younger than controls; however, TAPSE<\/jats:styled-content> was significantly lower in PH<\/jats:styled-content> patients after matching with controls by age. Tricuspid annular S' was decreased in PH<\/jats:styled-content> patients, but RVFAC<\/jats:styled-content> was similar. On multivariate analysis, tricuspid S' did not have a significant effect on the probability of PH<\/jats:styled-content> (P\u00a0=\u00a00.067). The odds of PH<\/jats:styled-content> significantly increased with each 1\u00a0mm decrease in TAPSE<\/jats:styled-content> (OR<\/jats:styled-content> 1.78, 95% CI<\/jats:styled-content> 1.26\u20132.45). Inter\u2010observer agreement for TAPSE<\/jats:styled-content> showed concordance correlation coefficient of 0.89.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>TAPSE<\/jats:styled-content> is a feasible and reproducible marker of RV<\/jats:styled-content> systolic function in infants with PH<\/jats:styled-content> and is superior to tricuspid annular S' and RVFAC<\/jats:styled-content>. Longitudinal studies are needed to evaluate the role of TAPSE<\/jats:styled-content> in serial evaluation of PH<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12797","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T09:09:04Z","timestamp":1412672944000},"page":"834-838","source":"Crossref","is-referenced-by-count":27,"title":["Tricuspid Annular Plane Systolic Excursion Is Reduced in Infants with Pulmonary Hypertension"],"prefix":"10.1111","volume":"32","author":[{"given":"Dala","family":"Zakaria","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology University of Arkansas for Medical Sciences, Arkansas Children's Hospital Little Rock Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Sachdeva","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology University of Arkansas for Medical Sciences, Arkansas Children's Hospital Little Rock Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Gossett","sequence":"additional","affiliation":[{"name":"Biostatistics Program Department of Pediatrics University of Arkansas for Medical Sciences Little Rock Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Tang","sequence":"additional","affiliation":[{"name":"Biostatistics Program Department of Pediatrics University of Arkansas for Medical Sciences Little Rock Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology University of Arkansas for Medical Sciences, Arkansas Children's Hospital Little Rock Arkansas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2012.11.009"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2010.05.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0095-5108(05)70109-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.180091"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3444"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1586\/erc.09.186"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.04.184"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071276"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03625.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.05.010"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-2167(02)00171-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.12.012"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.1.2.162"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-013-0286-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-547OC"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322006"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.03.026"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.06.004"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0213-z"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.05.050"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.01.017"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2012.01697.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.02.027"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.4.487"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.12797","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.12797","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:46:57Z","timestamp":1695570417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.12797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,7]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/echo.12797"],"URL":"https:\/\/doi.org\/10.1111\/echo.12797","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,7]]}}}