{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:22:47Z","timestamp":1791919367001,"version":"4.3.4"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) is associated with atrial remodeling. We investigate the abilities of preprocedural echocardiographic parameters reflecting atrial remodeling to predict <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence after radiofrequency catheter ablation (<jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>) for paroxysmal <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Preprocedural echocardiographic parameters were measured during sinus rhythm in 105 patients with <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> undergoing <jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content>. Electrical remodeling was assessed by the time from the onset of the P\u2010wave to the peak A\u2032\u2010wave on the tissue Doppler imaging (<jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>), functional remodeling was assessed by the left atrial appendage flow velocity (<jats:styled-content style=\"fixed-case\">LAAFV<\/jats:styled-content>), and structural remodeling was assessed by the left atrial volume index (<jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> LAAFV<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content> values were divided into tertiles, and their abilities to predict <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence were assessed using Cox regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>AF recurrence occurred in 39\/105 (37.1%) patients. After adjustment for confounders, the rate of AF recurrence was significantly higher in the highest tertile of PA\u2010TDI compared with the lowest tertile (\u2265151.3\u00a0msec vs. &lt;131.0\u00a0msec; hazard ratio [HR]: 2.477, 95% confidence interval [CI]: 1.031\u20135.950; P\u00a0=\u00a00.042), and in the lowest tertile of LAAFV compared with the highest tertile (&lt;48.5\u00a0cm\/sec vs. \u226564.9\u00a0cm\/sec; HR: 2.680, 95% CI: 1.136\u20136.318; P\u00a0=\u00a00.024). The risk of AF recurrence was also higher in the highest tertile of LAVI (\u226534.2 mL\/m<jats:sup>2<\/jats:sup>) compared with the lowest tertile, but this difference was not significant (HR: 2.146, 95% CI: 0.834\u20135.523; P\u00a0=\u00a00.113).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LAAFV<\/jats:styled-content> (reflecting functional remodeling) and <jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TDI<\/jats:styled-content> (reflecting electrical remodeling) are independent predictors of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence after <jats:styled-content style=\"fixed-case\">RFCA<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12823","type":"journal-article","created":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T07:00:28Z","timestamp":1414825228000},"page":"1101-1108","source":"Crossref","is-referenced-by-count":27,"title":["Left Atrial Appendage Flow Velocity and Time from P\u2010Wave Onset to Tissue Doppler\u2013Derived A' Predict Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation"],"prefix":"10.1111","volume":"32","author":[{"given":"Keiko","family":"Fukushima","sequence":"first","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noritoshi","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo 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Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuyuki","family":"Manaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyomi","family":"Ashihara","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morio","family":"Shoda","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Women's Medical University Tokyo 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