{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T07:18:10Z","timestamp":1721632690356},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,11,5]],"date-time":"2014-11-05T00:00:00Z","timestamp":1415145600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"China Education Department of Heilongjiang province science and technology research projects","award":["12531388"],"award-info":[{"award-number":["12531388"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the image quality and radiation dose of combined coronary and carotid\/cerebrovascular angiography with <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> gating and iterative reconstruction using 256\u2010slice <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> compared with the findings with the two examinations performed separately.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>One hundred sixty\u2010five consecutive patients underwent a single\u2010injection single\u2010pass combination of coronary and carotid\/cerebrovascular <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> angiography (group A), coronary <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> angiography alone (group B), or carotid\/cerebrovascular <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> angiography alone (group C). We assessed the image quality of the combined and separate examinations and calculated the respective effective radiation doses. We evaluated the differences in the proportions of image quality grade between the combination and single\u2010examination groups. Diagnostic performance of the combined scanning for detecting significant vascular stenosis has been compared with reference digital subtraction angiography (<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>) in the patient subgroup of group A.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference in age, body mass index (BMI), or gender distribution among the 3 groups (all P\u00a0&gt;\u00a00.05). But there was significant difference in scan length, DLP, and effective dose among the 3 groups (all P\u00a0&lt;\u00a00.05). There were no significant differences in the effective radiation dose of coronary scanning between groups A and B (P\u00a0&gt;\u00a00.05), while the effective radiation dose of carotid\/cerebrovascular scanning in group A was significantly lower than that in group C (P\u00a0&lt;\u00a00.05), and the total effective radiation dose in group A were relatively low (2.21\u00a0\u00b1\u00a01.38\u00a0mSv). The differences of the proportion of carotid\/cerebrovascular image quality grades between groups A and C were not significant (P\u00a0&gt;\u00a00.05). In a subgroup of group A of 30 patients with DSA, combined computed tomographic angiography successfully detected 56 coronary stenosis on per\u2010segment basis, and 62 stenosis on carotid and cerebral artery. The sensitivity, specificity, positive and negative predictive value (NPV) of coronary stenosis were 91.80%, 95.60%, 87.50% and 97.21%, respectively. The sensitivity, specificity, positive and NPV of carotid\/cerebrovascular stenosis were 93.55%, 94.68%, 92.06% and 95.70%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Combination of coronary and carotid\/cerebrovascular angiography with 256\u2010slice <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scanner with prospective <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> gating and iterative reconstruction produces diagnostic\u2010quality images of the coronary, carotid, and cerebrovascular systems in a single examination, using less contrast medium and a lower radiation dose than when the two examinations are performed separately. This novel technique has high accuracy in detecting significant stenosis in one image setting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12830","type":"journal-article","created":{"date-parts":[[2014,11,5]],"date-time":"2014-11-05T09:11:38Z","timestamp":1415178698000},"page":"1291-1298","source":"Crossref","is-referenced-by-count":7,"title":["Combining Coronary with Carotid and Cerebrovascular Angiography Using Prospective <scp>ECG<\/scp> Gating and Iterative Reconstruction with 256\u2010slice <scp>CT<\/scp>"],"prefix":"10.1111","volume":"32","author":[{"given":"Jin\u2010Ling","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bai\u2010Lu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan\u2010Ming","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010Wei","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo\u2010Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya\u2010Hua","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of CT The Second Affiliated Hospital of Harbin Medical University Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao\u2010Zhong","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Radiology The Fourth Affiliated Hospital of Harbin Medical University; Key Laboratory of Molecular Imaging in College of Heilongjiang Province Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)09457-3"},{"key":"e_1_2_6_3_1","first-page":"62","article-title":"Prognostic implications of intima\u2010media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris","volume":"22","author":"Duprez DA","year":"2005","journal-title":"Eur Heart J"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.1998.00350.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.01.014"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.06.001"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.01.039"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-006-0097-z"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.09.062"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-009-9439-0"},{"key":"e_1_2_6_11_1","first-page":"44","article-title":"256\u2010slice CT in systemic vascular applications","volume":"1","author":"Yan Y","year":"2011","journal-title":"J China\u2010Japan Friendship Hosp"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1822-7"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.51.4.5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0455.2003.00057.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-011-9921-3"},{"key":"e_1_2_6_16_1","first-page":"628","article-title":"Dual\u2010energy computed tomographic angiography of head and neck arteries with different contrast material doses in second generation dual\u2010source computed tomography system","volume":"32","author":"Chen Y","year":"2010","journal-title":"Acta Academiae Medicinae Sinicae"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1838-z"},{"key":"e_1_2_6_18_1","first-page":"1","article-title":"Managing patient dose in multi\u2010detector computed tomography (MDCT). 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