{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:57:50Z","timestamp":1790175470189,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,12,8]],"date-time":"2014-12-08T00:00:00Z","timestamp":1417996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Internal Research Support Programme of The University of Hong Kong","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Alteration of right ventricular (\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      ) function has been found in patients with pressure\u2010loaded left ventricles due to systemic hypertension and aortic stenosis. We tested the hypothesis that\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      mechanics are altered in adolescents and adults with repaired coarctation of the aorta (CoA).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010eight (15 male) patients, aged 23.7\u00a0\u00b1\u00a06.5\u00a0years, and 28 (14 male) controls were studied. M\u2010mode, tissue Doppler imaging, and speckle tracking echocardiography were performed to assess, respectively,\n                      <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>\n                      mass and\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      wall thickness,\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      myocardial tissue velocities, and deformation. Systolic (P\u00a0=\u00a00.14) and diastolic (P\u00a0=\u00a00.32) blood pressures were similar between patients and controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with controls, patients had significantly greater\n                      <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>\n                      mass (P\u00a0=\u00a00.016) and\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      anterior wall thickness (P\u00a0=\u00a00.012). Tricuspid annular systolic (P\u00a0&lt;\u00a00.001) and early diastolic (P\u00a0&lt;\u00a00.001) velocities, isovolumic acceleration (P\u00a0=\u00a00.004), global\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      systolic longitudinal strain (P\u00a0=\u00a00.03), systolic strain rate (P\u00a0=\u00a00.012), and early (P\u00a0=\u00a00.021) and late (P\u00a0=\u00a00.012) diastolic strain rates were significantly lower in patients than controls. Patients with an associated ventricular septal defect (n\u00a0=\u00a06) requiring closure compared to those without had even lower tricuspid annular systolic (P\u00a0=\u00a00.01) and early diastolic (P\u00a0=\u00a00.041) velocities. Left ventricular mass correlated negatively with\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      systolic strain rate (r\u00a0=\u00a0\u22120.27, P\u00a0=\u00a00.045) and tricuspid annular early diastolic velocity (r\u00a0=\u00a0\u22120.40, P\u00a0=\u00a00.002), while\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      anterior wall thickness correlated negatively with tricuspid annular systolic (r\u00a0=\u00a0\u22120.42, P\u00a0=\u00a00.002) and late diastolic (r\u00a0=\u00a0\u22120.40, P\u00a0=\u00a00.003) velocities, and positively with e\/a ratio (r\u00a0=\u00a00.31, P\u00a0=\u00a00.024).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      systolic and diastolic mechanics are impaired in patients late after repair of CoA and related to increased\n                      <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>\n                      mass and\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      thickness.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.12868","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T00:52:45Z","timestamp":1418086365000},"page":"797-804","source":"Crossref","is-referenced-by-count":8,"title":["Right Ventricular Myocardial Motion and Deformation in Adolescents and Young Adults after Repair of Coarctation of the Aorta"],"prefix":"10.1111","volume":"32","author":[{"given":"Vivian W. Y.","family":"Li","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatrics and Adolescent Medicine Queen Mary Hospital The University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiu\u2010fai","family":"Cheung","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Department of Pediatrics and Adolescent Medicine Queen Mary Hospital The University of Hong Kong Hong Kong 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