{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T22:44:41Z","timestamp":1771022681922,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,4,12]],"date-time":"2015-04-12T00:00:00Z","timestamp":1428796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>The patent ductus arteriosus (PDA) has diverse clinical and hemodynamic manifestations depending on its size and the degree of the ensuing left\u2010to\u2010right shunt. A small PDA that causes minor shunting has no major hemodynamic consequences. Conversely, a large PDA with a significant left\u2010to\u2010right shunt may lead to various hemodynamic abnormalities. These include left\u2010sided volume overload that may result in heart failure and\/or pulmonary hypertension, the latter being a flow\u2010dependent and mostly reversible phenomenon. The most feared complication is the development of severe and irreversible pulmonary hypertension (Eisenmenger physiology). In this manuscript, we provide examples of the various hemodynamic profiles of PDA as assessed by echocardiography in the adult population.<\/jats:p>","DOI":"10.1111\/echo.12943","type":"journal-article","created":{"date-parts":[[2015,4,13]],"date-time":"2015-04-13T04:26:59Z","timestamp":1428899219000},"page":"1172-1178","source":"Crossref","is-referenced-by-count":16,"title":["The Various Hemodynamic Profiles of the Patent Ductus Arteriosus in Adults"],"prefix":"10.1111","volume":"32","author":[{"given":"Bahaa M.","family":"Fadel","sequence":"first","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dania","family":"Mohty","sequence":"additional","affiliation":[{"name":"CHU Limoges Limoges France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysha","family":"Husain","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Dahdouh","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Al\u2010Admawi","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Pergola","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Di Salvo","sequence":"additional","affiliation":[{"name":"King Faisal Specialist Hospital &amp; Research Center Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,12]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.592063"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.43.3.323"},{"key":"e_1_2_3_4_1","first-page":"863","volume-title":"Principles and Practice of Echocardiography","author":"Weyman AE","year":"1994"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.5.1081"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(94)90415-4"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(93)90144-X"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12531"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.60.2.355"},{"key":"e_1_2_3_10_1","doi-asserted-by":"crossref","first-page":"V45","DOI":"10.1161\/01.CIR.38.1S5.V-45","article-title":"Patent ductus arteriosus with special reference to patients with pulmonary hypertension","volume":"38","author":"Espino\u2010Vela J","year":"1968","journal-title":"Circulation"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.52.1.157"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.12943","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.12943","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T08:14:30Z","timestamp":1696320870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.12943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,12]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1111\/echo.12943"],"URL":"https:\/\/doi.org\/10.1111\/echo.12943","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,12]]}}}