{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T13:10:35Z","timestamp":1712754635637},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,6]],"date-time":"2015-06-06T00:00:00Z","timestamp":1433548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Transcatheter closure is a well\u2010established treatment for patients with atrial septal defect (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>), but long\u2010term outcome prognostic factors for adults have not been fully identified yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010nine consecutive patients (age 57\u00a0\u00b1\u00a017\u00a0years, 59% female), who underwent transcatheter closure of <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>, were the subjects of this study. Transthoracic echocardiography was performed before and midterm after the procedure (6\u00a0\u00b1\u00a01\u00a0months). Isovolumic contraction peak velocity (<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content>) was measured at the lateral site of the tricuspid annulus using spectral tissue Doppler imaging, and \u0394<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content> was determined as the absolute change at midterm follow\u2010up. Long\u2010term unfavorable outcome events, tracked for 19\u00a0\u00b1\u00a09\u00a0months, were prespecified as primary end points comprising newly developed atrial fibrillation, cerebral infarction, and heart failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Symptomatic improvement, defined as an improvement in New York Heart Association functional class by one grade or more at midterm after the procedure, was observed in 24 patients (49%), and the remaining 25 (51%) were classified as not symptomatically improved. \u0394<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content> was significantly larger for patients with symptomatic improvement than for those without (from 11.5\u00a0\u00b1\u00a04.3\u00a0cm\/s to 14.2\u00a0\u00b1\u00a03.7\u00a0cm\/s vs. from 11.8\u00a0\u00b1\u00a04.1\u00a0cm\/s to 12.5\u00a0\u00b1\u00a02.9\u00a0cm\/s; P\u00a0=\u00a00.045). An important finding of the multivariate Cox proportional\u2010hazards analysis was that only \u0394<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content> was independently associated with cardiovascular events (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>: 0.701; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.537\u20130.916; P\u00a0=\u00a00.01). Kaplan\u2013Meier analysis showed that more patients with enhanced \u0394<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content> presented with favorable long\u2010term outcome than those with diminished \u0394<jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content> (log\u2010rank P\u00a0=\u00a00.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">IVV<\/jats:styled-content>, which is a less volume\u2010sensitive parameter, can be useful for comprehensive evaluation of <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> patients referred for transcatheter closure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.12982","type":"journal-article","created":{"date-parts":[[2015,6,6]],"date-time":"2015-06-06T08:12:10Z","timestamp":1433578330000},"page":"23-29","source":"Crossref","is-referenced-by-count":4,"title":["Utility of Isovolumic Contraction Peak Velocity for Evaluation of Adult Patient Status after Transcatheter Closure of Atrial Septal Defect"],"prefix":"10.1111","volume":"33","author":[{"given":"Takuma","family":"Sawa","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidekazu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Motoji","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mana","family":"Hiraishi","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhide","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Ryo","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe 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