{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:39:57Z","timestamp":1787506797547,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,22]],"date-time":"2015-06-22T00:00:00Z","timestamp":1434931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Scientific Research Project","award":["2012225098"],"award-info":[{"award-number":["2012225098"]}]},{"name":"Science and Technology Agency of Liaoning province, China"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,1]]},"abstract":"\n Background<\/jats:title>\n \n Fetal interrupted aortic arch (IAA) is a rare cardiac anomaly and its prenatal diagnosis is challenging. The purpose of our report is to evaluate the use of two\u2010dimensional echocardiography (2\n DE<\/jats:styled-content>\n ) and 4D echocardiography with B\u2010flow imaging and spatiotemporal image correlation (4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n ) in detecting IAA type A (\n IAA<\/jats:styled-content>\n \u2010A).\n <\/jats:p>\n <\/jats:sec>\n \n Materials & Methods<\/jats:title>\n \n Twenty\u2010three cases of confirmed\n IAA<\/jats:styled-content>\n \u2010A identified by fetal echocardiography were involved in the study. The fetal echocardiography image data were reviewed to analyze the ratio of right ventricle to left ventricle (\n RV<\/jats:styled-content>\n \/\n LV<\/jats:styled-content>\n ) diameter, the ratio of main pulmonary artery to ascending aorta (\n MPA<\/jats:styled-content>\n \/\n AAO<\/jats:styled-content>\n ) diameter, and the correlation of\n RV<\/jats:styled-content>\n \/\n LV<\/jats:styled-content>\n diameter ratio and size of ventricular septal defect (\n VSD<\/jats:styled-content>\n ). 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n was performed in 21 fetuses using the sagittal view (4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u2010sagittal) and the four\u2010chamber view (4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u20104\n CV<\/jats:styled-content>\n ) as initial planes of view. An additional 183 normal fetuses were also included in our study.\n RV<\/jats:styled-content>\n \/\n LV<\/jats:styled-content>\n and\n MPA<\/jats:styled-content>\n \/\n AAO<\/jats:styled-content>\n ratios were calculated and compared with that of\n IAA<\/jats:styled-content>\n \u2010A fetuses. Fetal 2\n DE<\/jats:styled-content>\n , 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u2010sagittal, and 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u20104\n CV<\/jats:styled-content>\n were used to visualize the aortic arch and its associated neck vessels. Six subgroups were evaluated according to gestational age.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Fetal 2\n DE<\/jats:styled-content>\n , 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u2010sagittal, and 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u20104\n CV<\/jats:styled-content>\n made the correct prenatal diagnosis of\n IAA<\/jats:styled-content>\n \u2010A in 19\/23 (82.6%), 14\/21 (66.7%), and 19\/21 (90.5%) of patients, respectively. A significantly enlarged\n MPA<\/jats:styled-content>\n combined with symmetric ventricles was found in the\n IAA<\/jats:styled-content>\n \u2010A fetuses, while the size of the\n VSD<\/jats:styled-content>\n was negatively correlated with\n RV<\/jats:styled-content>\n \/\n LV<\/jats:styled-content>\n ratio. 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u2010sagittal and 4D\n BF<\/jats:styled-content>\n \u2010\n STIC<\/jats:styled-content>\n \u20104\n CV<\/jats:styled-content>\n were better than traditional 2D ultrasound in detecting the aortic arch and neck vessels between 17 and 28 gestational weeks and 29 to 40 gestational weeks in normal fetuses.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n It is demonstrated that\n IAA<\/jats:styled-content>\n \u2010A could be diagnosed by traditional fetal echocardiography, while 4D technique could better display the anatomic structure and the spatial relationships of the great arteries. Use of volume reconstruction may promote its clinical usage and help prenatal diagnosis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/echo.12996","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T01:09:15Z","timestamp":1435021755000},"page":"90-98","source":"Crossref","is-referenced-by-count":22,"title":["Prenatal Diagnosis of Fetal Interrupted Aortic Arch Type A by Two\u2010Dimensional Echocardiography and Four\u2010Dimensional Echocardiography with B\u2010Flow Imaging and Spatiotemporal Image Correlation"],"prefix":"10.1111","volume":"33","author":[{"given":"Dongyu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailu","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Sonography Shengjing Hospital of China Medical University Heping District Shenyang 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