{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:05:17Z","timestamp":1783613117037,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Few data have existed on myocardial postsystolic shortening (<jats:styled-content style=\"fixed-case\">PSS<\/jats:styled-content>) accounting for left ventricular (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) diastolic dysfunction in systemic hypertension. We examined this relationship, along with clinical and other cardiac parameters, in asymptomatic patients with hypertension.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed 104 patients on pharmacological treatment for hypertension who had no signs or symptoms of heart failure for conventional and speckle tracking echocardiography. The sum of the postsystolic index for multiple <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> segments (total <jats:styled-content style=\"fixed-case\">PSI<\/jats:styled-content>) and global longitudinal strain (<jats:styled-content style=\"fixed-case\">GLS<\/jats:styled-content>) was computed and used as measures for global <jats:styled-content style=\"fixed-case\">PSS<\/jats:styled-content> and myocardial systolic function, respectively. The tissue Doppler e\u2019 and the speckle tracking\u2013derived global strain rate during early diastole (e'sr) were obtained as indicators of <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> relaxation. The circumferential end\u2010systolic stress was also determined noninvasively and substituted for a measure of myocardial afterload.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Main variables that correlated with the e\u2019 and e'sr were shown to be age, <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> mass index, left atrial volume index, <jats:styled-content style=\"fixed-case\">GLS<\/jats:styled-content>, and the total <jats:styled-content style=\"fixed-case\">PSI<\/jats:styled-content>. Multivariate analysis including gender, circumferential end\u2010systolic stress, and the use of calcium channel blockers as possible covariates revealed that age (\u03b2\u00a0=\u00a0\u22120.29, P\u00a0=\u00a00.002), total <jats:styled-content style=\"fixed-case\">PSI<\/jats:styled-content> (\u03b2\u00a0=\u00a0\u22120.26, P\u00a0=\u00a00.008), and <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> mass index (\u03b2\u00a0=\u00a0\u22120.25, P\u00a0=\u00a00.017) were significant independent determinants of e\u2019 and that age (\u03b2\u00a0=\u00a0\u22120.34, P\u00a0&lt;\u00a00.001) and <jats:styled-content style=\"fixed-case\">GLS<\/jats:styled-content> (\u03b2\u00a0=\u00a0\u22120.28, P\u00a0=\u00a00.006) were of e'sr.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings indicate that while depending on the degree of <jats:styled-content style=\"fixed-case\">GLS<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> PSS<\/jats:styled-content> may affect diastolic relaxation in patients with asymptomatic, but treated, hypertensive patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13022","type":"journal-article","created":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T07:11:04Z","timestamp":1438413064000},"page":"216-222","source":"Crossref","is-referenced-by-count":11,"title":["Association between Left Ventricular Postsystolic Shortening and Diastolic Relaxation in Asymptomatic Patients with Systemic Hypertension"],"prefix":"10.1111","volume":"33","author":[{"given":"Shimpei","family":"Nogi","sequence":"first","affiliation":[{"name":"Department of Cardiology Osaka Medical College Takatsuki Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahide","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Cardiology Osaka Medical College Takatsuki Osaka 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