{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T20:43:29Z","timestamp":1757450609138},"reference-count":4,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,23]],"date-time":"2015-10-23T00:00:00Z","timestamp":1445558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p>The long\u2010term sequelae of mantle radiotherapy include lung disease and cardiac disorders. Dyspnea on exertion is a common complaint and can be due to one or more pathologies. We describe a case of mantle radiotherapy\u2010induced mitral stenosis, characterized by aorto\u2010mitral continuity calcification and absent commissural fusion which precludes balloon valvotomy. The latency period is long, and this patient presented 42 years after radiotherapy. Importantly, as previously described with radiation\u2010induced valve disease, significant mitral stenosis developed 10 years after surgery for significant aortic stenosis. Two\u2010dimensional and three\u2010dimensional transthoracic and transesophageal echocardiography should be considered during assessment of symptomatic survivors of Hodgkin's disease where the index of suspicion for valvular stenosis increases over time. Given the natural history of mantle radiation valvular disease, a lower threshold for surgical intervention in radiation\u2010induced mitral stenosis may need to be considered if cardiac surgery is planned for other reasons in order to avoid repeated sternotomy in patients with prior irradiation.<\/jats:p>","DOI":"10.1111\/echo.13092","type":"journal-article","created":{"date-parts":[[2015,10,23]],"date-time":"2015-10-23T06:24:46Z","timestamp":1445581486000},"page":"317-319","source":"Crossref","is-referenced-by-count":5,"title":["Echocardiographic Assessment of Mantle Radiation Mitral Stenosis"],"prefix":"10.1111","volume":"33","author":[{"given":"Rachel","family":"Bastiaenen","sequence":"first","affiliation":[{"name":"St. George's Hospital London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Sneddon","sequence":"additional","affiliation":[{"name":"East Surrey Hospital Redhill United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajan","family":"Sharma","sequence":"additional","affiliation":[{"name":"St. George's Hospital London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,23]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6605191"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.21.2831"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000031"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl206"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13092","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T19:26:15Z","timestamp":1695497175000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,23]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/echo.13092"],"URL":"https:\/\/doi.org\/10.1111\/echo.13092","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,23]]}}}