{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:40:35Z","timestamp":1777542035327,"version":"3.51.4"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,11,2]],"date-time":"2015-11-02T00:00:00Z","timestamp":1446422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>On\u2010site transthoracic echocardiography (<jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content>) to guide the transcutaneous closure of secundum\u2010type atrial septal defects (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>s) in the catheterization laboratory remains unclear, especially in adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2005 and 2012, a total of 82 adults underwent transcutaneous closure of <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>s. The initial 15 cases underwent the procedure with both on\u2010site transesophageal echocardiography (<jats:styled-content style=\"fixed-case\">TEE<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> monitoring. Since January 2008, a total of 67 patients underwent on\u2010site <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> alone to guide the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 82 adult patients who underwent a transcutaneous closure of the secundum\u2010type <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> procedure, all had successful closure of the defects, and no periprocedural adverse complications occurred. No statistical significance was observed in the successful complete shunt closure rate between the <jats:styled-content style=\"fixed-case\">TEE<\/jats:styled-content> plus <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> groups during sequential follow\u2010up (postprocedure 24 hour [87% vs. 92%],1 month [93% vs. 95%], 3 month [93% vs. 97%], and 12 month [93% vs. 97%], P &gt; 0.05, respectively) nor was a significant difference observed between the two groups, including decreased right ventricular dimension (29.5 \u00b1 3.3 vs. 32.0 \u00b1 4.9 mm, 26.5 \u00b1 3.0 vs. 28.7 \u00b1 4.6 mm, 26.2 \u00b1 3.1 vs. 28.2 \u00b1 4.8 mm, and 25.6 \u00b1 2.8 vs. 27.7 \u00b1 4.7 mm, P &gt; 0.05, respectively) or increased left ventricular end\u2010diastolic dimension (41.1 \u00b1 2.0 vs. 42.6 \u00b1 3.0 mm, 44.3 \u00b1 2.7 vs. 45.5 \u00b1 3.1 mm, 44.2 \u00b1 2.8 vs. 45.4 \u00b1 3.1 mm, 44.9 \u00b1 2.7 vs. 45.8 \u00b1 2.6 mm, P &gt; 0.05, respectively) before the procedure, and at the 3\u2010, 6\u2010, and 12\u2010month follow\u2010up evaluations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study showed that <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content> guidance alone may be considered efficacious and safe as <jats:styled-content style=\"fixed-case\">TEE<\/jats:styled-content> during a transcutaneous <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> occlusion procedure in select adults.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13106","type":"journal-article","created":{"date-parts":[[2015,11,2]],"date-time":"2015-11-02T07:18:40Z","timestamp":1446448720000},"page":"579-585","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy and Safety of Transthoracic Echocardiography Alone in Transcatheter Closure of Secundum\u2010Type Atrial Septal Defects in 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