{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T11:21:44Z","timestamp":1720437704627},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,12,15]],"date-time":"2015-12-15T00:00:00Z","timestamp":1450137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81301234","81371576"],"award-info":[{"award-number":["81301234","81371576"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007279","name":"Shanghai Municipal Health Bureau","doi-asserted-by":"publisher","award":["20134144"],"award-info":[{"award-number":["20134144"]}],"id":[{"id":"10.13039\/501100007279","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate right ventricular (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>) global and regional systolic function in patients with atrial septal defect (<jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>) before and after percutaneous closure using real time three\u2010dimensional echocardiography (<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content> was performed in 81 patients with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> within 24\u00a0hours before and after percutaneous closure to obtain <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> global and regional ejection fraction (<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>) in three compartments (inflow, body, and outflow). <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> fractional area change (<jats:styled-content style=\"fixed-case\">FAC<\/jats:styled-content>), tricuspid annular plane systolic excursion (<jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>), peak tricuspid systolic velocity (S), and pulmonary vascular resistance (<jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content>) were recorded. Forty matched normal adults were included as controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When compared with controls, <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> global and regional <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> were decreased in preclosure patients (P<jats:italic>\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). <jats:styled-content style=\"fixed-case\">FAC<\/jats:styled-content> was lower while <jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content> and S were higher in preclosure patients than in controls (P\u00a0&lt;<jats:italic>\u00a0<\/jats:italic>0.05). After closure, <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> systolic function parameters were all reduced (P\u00a0&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Regional <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> in the body compartment was the lowest among the three compartments in <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> patients (P\u00a0&lt;\u00a00.05). Procedural percentage changes of <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> global <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> and regional <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> in the inflow compartment were lower than those of two\u2010dimensional systolic function parameters (P\u00a0&lt;\u00a00.05). <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> global and regional <jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content> in the inflow compartment were negatively correlated with <jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content> in patients after closure (r<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>\u22120.601, \u22120.543, P\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> global and regional systolic functions are impaired in open and closed <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content>\u2010derived systolic function parameters are negatively correlated with <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> after load. <jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>3<jats:styled-content style=\"fixed-case\">DE<\/jats:styled-content> has potential value in the evaluation of <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> systolic function in patients with <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13134","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T04:34:42Z","timestamp":1450240482000},"page":"596-605","source":"Crossref","is-referenced-by-count":13,"title":["Three\u2010Dimensional Echocardiography in the Evaluation of Right Ventricular Global and Regional Systolic Function in Patients with Atrial Septal Defect before and after Percutaneous Closure"],"prefix":"10.1111","volume":"33","author":[{"given":"Dehong","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Echocardiography Zhongshan Hospital of Fudan University Shanghai China"},{"name":"Shanghai Institute of Cardiovascular Diseases Shanghai China"},{"name":"Shanghai Institute of Medical Imaging Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leilei","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of 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