{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T04:00:23Z","timestamp":1772596823848,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T00:00:00Z","timestamp":1454025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>In our study, we aimed to evaluate the effect of weight loss on left and right ventricular functions in obese patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty patients with a <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> greater than 30 kg\/m<jats:sup>2<\/jats:sup> and without any exclusion criteria were included in the study. Left ventricular systolic and diastolic functions were assessed with conventional and tissue Doppler echocardiography (<jats:styled-content style=\"fixed-case\">TDE<\/jats:styled-content>). At the end of 3 months, echocardiographic examination was repeated in patients with weight loss for cardiac function evaluation and it was compared to the baseline echocardiographic parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At the end of 3 months of weight loss period, conventional Doppler echocardiography revealed an improvement in diastolic functions with an increase in mitral E\u2010wave, a decrease in mitral A\u2010wave and an increase in E\/A ratio. Deceleration time and isovolumetric relaxation time were ascertained shortened and Tei index decreased. <jats:styled-content style=\"fixed-case\">TDE<\/jats:styled-content> showed an increase in left ventricular lateral wall systolic wave (Sm) and E\u2010wave velocity (Em). Mitral septal annular isovolumetric acceleration time (<jats:styled-content style=\"fixed-case\">IVA<\/jats:styled-content>), Sm and Em, were found to be increased, whereas Tei index was ascertained reduced. Right ventricular tissue Doppler examination following weight loss revealed an increase in <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\u2010 <jats:styled-content style=\"fixed-case\">IVA<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> RV<\/jats:styled-content>\u2010Sm, and <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\u2010Em, and a decrease in Tei index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We disclosed that left ventricular structural changes and diastolic dysfunction occur in obese patients, and by weight loss, these abnormalities may be reversible which we demonstrated both by conventional and <jats:styled-content style=\"fixed-case\">TDE<\/jats:styled-content>. In addition, obesity might impair <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> function as well, and we observed an enhancement in right ventricular functions by weight loss.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13185","type":"journal-article","created":{"date-parts":[[2016,1,30]],"date-time":"2016-01-30T04:40:50Z","timestamp":1454128850000},"page":"854-861","source":"Crossref","is-referenced-by-count":6,"title":["Assessment of Impact of Weight Loss on Left and Right Ventricular Functions and Value of Tissue Doppler Echocardiography in Obese Patients"],"prefix":"10.1111","volume":"33","author":[{"given":"Isa Oner","family":"Yuksel","sequence":"first","affiliation":[{"name":"Department of Cardiology Antalya Education and Research Hospital Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nihal","family":"Akar Bayram","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ankara Ataturk Education and Research 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