{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T04:37:46Z","timestamp":1781498266396,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,2,28]],"date-time":"2016-02-28T00:00:00Z","timestamp":1456617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,7]]},"abstract":"Background<\/jats:title>Recent reports have demonstrated the adverse effects of venous congestion on renal function in patients having heart failure. None of the above trials, however, included patients with acute ischemia.<\/jats:p><\/jats:sec>Hypothesis<\/jats:title>Echocardiographic correlates of increased right ventricular afterload would be associated with an increased risk of acute kidney injury (AKI<\/jats:styled-content>) in ST<\/jats:styled-content> elevation myocardial infarction (STEMI<\/jats:styled-content>) patients undergoing primary percutaneous coronary intervention (PCI<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>We conducted a retrospective study of consecutive 930 STEMI<\/jats:styled-content> patients who underwent primary PCI<\/jats:styled-content> and had a full echocardiography study performed within 72 hours of hospital admission between June 2011 and December 2014.<\/jats:p><\/jats:sec>Results<\/jats:title>Echocardiography demonstrated that patients with AKI<\/jats:styled-content> had significantly lower left ventricular (LV<\/jats:styled-content>) ejection fraction, higher systolic pulmonary artery pressure (SPAP<\/jats:styled-content>), and right atrial pressures (P < 0.001 for all). Following the performance of logistic multivariate analysis model, SPAP<\/jats:styled-content> (HR<\/jats:styled-content> 1.07, 95% CI<\/jats:styled-content> 1.04\u20131.11; P < 0.001) and LV<\/jats:styled-content> ejection fraction (HR<\/jats:styled-content> 0.95, 95% CI<\/jats:styled-content> 0.92\u20130.99; P = 0.03) emerged as independent predictors of AKI<\/jats:styled-content>. On receiver operating characteristic (ROC<\/jats:styled-content>) curve analysis, the optimal cutoff value of SPAP<\/jats:styled-content> to predict AKI<\/jats:styled-content> was measured as more than 32 mmHg, with 71% sensitivity and 62% specificity (AUC<\/jats:styled-content> 0.739, 95% CI<\/jats:styled-content> 0.671\u20130.806, P < 0.001).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Among STEMI<\/jats:styled-content> patients undergoing primary PCI<\/jats:styled-content>, worse LV<\/jats:styled-content> function and elevated SPAP<\/jats:styled-content> were associated with increased risk of AKI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13206","type":"journal-article","created":{"date-parts":[[2016,2,29]],"date-time":"2016-02-29T04:29:04Z","timestamp":1456720144000},"page":"956-961","source":"Crossref","is-referenced-by-count":5,"title":["Relation of Pulmonary Artery Pressure and Renal Impairment in ST<\/scp> Segment Elevation Myocardial Infarction Patients"],"prefix":"10.1111","volume":"33","author":[{"given":"Yacov","family":"Shacham","sequence":"first","affiliation":[{"name":"Department of Cardiology Tel\u2010Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Gal\u2010Oz","sequence":"additional","affiliation":[{"name":"Department of Nephrology Tel\u2010Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Topilsky","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tel\u2010Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gad","family":"Keren","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tel\u2010Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaron","family":"Arbel","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tel\u2010Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine Tel\u2010Aviv University Tel\u2010Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-014-0680-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.09.055"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.9.987"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.08.007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2015.03.031"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.04.023"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2007.05.010"},{"key":"e_1_2_6_9_1","first-page":"1","article-title":"Cardiorenal syndromes. 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