{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:56:37Z","timestamp":1779378997307,"version":"3.53.1"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T00:00:00Z","timestamp":1459555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Capital Health Development Research Project","award":["2014-4-4034"],"award-info":[{"award-number":["2014-4-4034"]}]},{"name":"Union Youth Fund","award":["2012-XHQN03"],"award-info":[{"award-number":["2012-XHQN03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,7]]},"abstract":"Introduction<\/jats:title>Percutaneous patent ductus arteriosus (PDA<\/jats:styled-content>) occlusion has become the preferred therapeutic option, which uses fluoroscopy as the guidance. To reduce the x\u2010ray exposure, PDA<\/jats:styled-content> occlusion using the Amplatzer Duct Occluder II<\/jats:styled-content> (ADO II<\/jats:styled-content>) under guidance of transthoracic echocardiography only was conducted. This single center study aims to access the safety and efficiency of this new strategy.<\/jats:p><\/jats:sec>Methods and Results<\/jats:title>From June 2013 to May 2015, 63 consecutive PDA<\/jats:styled-content> patients underwent transthoracic echocardiography\u2010guided PDA<\/jats:styled-content> occlusion through the femoral artery. Outpatient follow\u2010up was conducted at 1, 3, and 6 months, and yearly. Sixty\u2010two patients successfully underwent echocardiography\u2010guided percutaneous PDA<\/jats:styled-content> occlusion. One patient was converted to minimally invasive transthoracic occlusion due to failure of delivery sheath passage through tortuous PDA<\/jats:styled-content>. Mean procedure duration was 24.3 \u00b1 7.0 minutes; ADO II<\/jats:styled-content> diameter averaged 4.6 \u00b1 0.9 mm; 8 cases showed traces of residual shunt immediately after operation which resolved after 24 hours; and mean hospital stay was 3.4 \u00b1 0.5 days. There was no occluder migration, hemolysis, pericardial effusion, pulmonary branch or aortic stenosis at mean 13.5 \u00b1 4.8 months follow\u2010up.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>This study demonstrated that percutaneous PDA<\/jats:styled-content> occlusion can be successfully performed under guidance of transthoracic echocardiography only and appears safe and effective while avoiding radiation and contrast agent use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13207","type":"journal-article","created":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T20:37:14Z","timestamp":1459629434000},"page":"1040-1045","source":"Crossref","is-referenced-by-count":25,"title":["Transthoracic Echocardiography\u2010Guided Percutaneous Patent Ductus Arteriosus Occlusion: A New Strategy for Interventional Treatment"],"prefix":"10.1111","volume":"33","author":[{"given":"Xiang\u2010Bin","family":"Pan","sequence":"first","affiliation":[{"name":"National Center for Cardiovascular Disease China & Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Bin","family":"Ouyang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China & Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou\u2010Zheng","family":"Wang","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China & Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Liu","sequence":"additional","affiliation":[{"name":"National Center for Cardiovascular Disease China & Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 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