{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T08:18:07Z","timestamp":1782634687904,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,3,23]],"date-time":"2016-03-23T00:00:00Z","timestamp":1458691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Ulcerative colitis (<jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>) is a common inflammatory bowel disease causing systemic inflammation, which may also affect the cardiovascular system, as well as other organ systems. The aim of the current study was to evaluate left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) mechanical functions and duration of atrial electromechanical delay (<jats:styled-content style=\"fixed-case\">AEMD<\/jats:styled-content>) with echocardiography in patients with <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A total of 91 patients, 45 with <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> (Group 1) and 46 healthy individuals as control (Group 2) were included in the study. The demographic and laboratory data were recorded, and echocardiographic measurements were taken for all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the evaluation of basal clinical and laboratory findings, no difference was detected between the two groups, except for white blood cell count (<jats:styled-content style=\"fixed-case\">WBC<\/jats:styled-content>) (8.26 \u00b1 2.71 vs. 7.06 \u00b1 1.70, P = 0.013) and high\u2010sensitivity C\u2010reactive protein (Hs\u2010<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>; 3.4 \u00b1 1.7 vs. 1.0 \u00b1 0.8, P &lt; 0.001). The echocardiographic assessment revealed that the diastolic parameters such as E\u2010, E\/A\u2010, and E\u2010 waves decreased in the <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> group when compared to the control group. <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> mechanical functions were different between groups, except for left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) maximal volume: <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> minimum volume (22.2 \u00b1 12.9 vs. 15.3 \u00b1 4.7, P = 0.001), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume before atrial systole (29.9 \u00b1 14.2 vs. 24.2 \u00b1 4.9, P = 0.021), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> ejection fraction (27.4 \u00b1 16.5 vs. 38.6 \u00b1 10.1, P &lt; 0.001), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> total emptying volume (17.9 \u00b1 6.9 vs. 21.9 \u00b1 5.9, P = 0.004), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> active emptying fraction (27.4 \u00b1 16.5 vs. 38.6 \u00b1 10.1, P &lt; 0.001), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> active emptying volume (7.7 \u00b1 3.6 vs. 9.4 \u00b1 2.9, P = 0.013), <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> passive emptying fraction (26.8 \u00b1 10.2 vs. 33.2 \u00b1 9.2, P = 0.002), and <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> passive emptying volume (10.3 \u00b1 4.9 vs. 12.5 \u00b1 4.5, P = 0.029). There was a significant difference between the groups in terms of <jats:styled-content style=\"fixed-case\">AEMD<\/jats:styled-content> durations, except time interval from the onset of the P\u2010wave on the surface <jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> to the peak of the late diastolic wave (<jats:styled-content style=\"fixed-case\">PA<\/jats:styled-content>) of the tricuspid valve. The correlation analysis revealed that age and duration of disease were correlated with <jats:styled-content style=\"fixed-case\">AEMD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The current study reported that <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> volume and mechanical functions degenerated and <jats:styled-content style=\"fixed-case\">AEMD<\/jats:styled-content> increased in patients with <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> when compared to the control group. These findings demonstrate that <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> may have effects on <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> electromechanical functions related to duration of disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13213","type":"journal-article","created":{"date-parts":[[2016,3,24]],"date-time":"2016-03-24T05:21:36Z","timestamp":1458796896000},"page":"970-976","source":"Crossref","is-referenced-by-count":18,"title":["Assessment of Atrial Electromechanical Delay and Left Atrial Mechanical Functions in Patients with Ulcerative Colitis"],"prefix":"10.1111","volume":"33","author":[{"given":"Gokay","family":"Nar","sequence":"first","affiliation":[{"name":"Department of Cardiology Faculty of Medicine Ahi Evran University Kirsehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Ergul","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ahi Evran 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