{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T14:40:09Z","timestamp":1784990409428,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T00:00:00Z","timestamp":1466985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:label\/><jats:p>Ischemic mitral regurgitation (MR) is an established adverse prognostic factor after myocardial infarction (MI). Functional ischemic mitral regurgitation in acute phase of MI remains under\u2010investigated due to its often transient and dynamic nature. We aimed to assess left ventricular (LV) mechanics by speckle\u2010tracking echocardiography in acute inferoposterior MI and ischemic mitral regurgitation (MR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010nine patients with no structural cardiac valve abnormalities and first acute inferoposterior MI were prospectively enrolled into the study. Two\u2010dimensional transthoracic echocardiography for regional myocardial function and valve assessment was performed within 48 hours of presentation after reperfusion therapy (percutaneous coronary intervention). Based on degree of MR, patients were divided into no significant MR (NMR) group (N = 34, with no or mild (grade 0\u2013I) MR) and ischemic MR (IMR) group (N = 35, with grade \u22652 MR). Thirty\u2010five age\u2010 and gender\u2010matched healthy individuals served as a normal reference group. Offline 2D speckle tracking analysis was performed with GE EchoPAC software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LV ejection fraction and longitudinal myocardial deformation parameters were significantly better in healthy subjects, but did not differ between both study groups. All circumferential myocardial deformation parameters were significantly worse in IMR group compared to healthy subjects and NMR group. Global, basal, and mid\u2010ventricular radial strain was significantly lower in IMR group compared to both\u2014healthy subjects and NMR group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ischemic mitral regurgitation in acute inferoposterior MI is associated with worse radial and circumferential LV deformation parameters assessed by 2D speckle tracking echocardiography.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13240","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T03:08:04Z","timestamp":1467169684000},"page":"1131-1142","source":"Crossref","is-referenced-by-count":7,"title":["Left Ventricular Mechanics in Functional Ischemic Mitral Regurgitation in Acute Inferoposterior Myocardial Infarction"],"prefix":"10.1111","volume":"33","author":[{"given":"Zivile","family":"Valuckiene","sequence":"first","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justas","family":"Ovsianas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"},{"name":"Klinikum Gutersloh Reckenberger Stra\u00dfe 19 33332 Gutersloh Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruta","family":"Ablonskyte\u2010Dudoniene","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaida","family":"Mizariene","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Melinyte","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaldas","family":"Jurkevicius","sequence":"additional","affiliation":[{"name":"Department of Cardiology Lithuanian University of Health Sciences Eiveniu 2, LT\u201050009, Kaunas Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.04.001"},{"key":"e_1_2_6_3_1","first-page":"403","article-title":"Cardiac mechanics evaluated by speckle tracking echocardiography","volume":"102","author":"Abduch MC","year":"2014","journal-title":"Arq Bras 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