{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:27Z","timestamp":1787014107490,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,4,24]],"date-time":"2016-04-24T00:00:00Z","timestamp":1461456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Percutaneous atrial septal defect (\n                      <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>\n                      ) device closure is a safe and effective means of reducing or eliminating interatrial shunting. The response of the right heart to device closure is incompletely understood.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      To evaluate the effects of transcatheter closure of secundum\n                      <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>\n                      on right ventricle size and function, that is, both systolic and diastolic by transthoracic echocardiography (\n                      <jats:styled-content style=\"fixed-case\">TTE<\/jats:styled-content>\n                      ) over a 6\u2010month period.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seventy\u2010three patients had 73 device implantations. The patients were assessed with echocardiography before and at 1 and 6 months after procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean age was 26 \u00b1 17 years. Mean\n                      <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>\n                      size indexed to body surface area (\n                      <jats:styled-content style=\"fixed-case\">BSA<\/jats:styled-content>\n                      ) was 19.1 \u00b1 8.6 mm\/m\n                      <jats:sup>2<\/jats:sup>\n                      . The device size ranged from 12 to 42 mm. One month after closure, there were statistically significant decreases in right ventricular (\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      ) basal diameter (3.5 \u00b1 0.7 cm vs. 4.2 \u00b1 0.8 cm),\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>\n                      end\u2010diastolic diameter ratio (0.9 \u00b1 0.1 vs. 1.2 \u00b1 0.2), left ventricular eccentricity index (\n                      <jats:styled-content style=\"fixed-case\">LVEI<\/jats:styled-content>\n                      ) (1.0 \u00b1 0.1 vs. 1.2 \u00b1 0.2), right atrial (\n                      <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>\n                      ) major dimension (4.4 \u00b1 0.8 cm vs. 4.8 \u00b1 1.0 cm),\n                      <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>\n                      end\u2010systolic area (13.2 \u00b1 4.6 cm\n                      <jats:sup>2<\/jats:sup>\n                      vs. 18.5 \u00b1 6.7 cm\n                      <jats:sup>2<\/jats:sup>\n                      ), tricuspid annular plane systolic excursion (\n                      <jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>\n                      ) (2.2 \u00b1 1.8 cm vs. 2.8 \u00b1 0.5 cm), tricuspid annular systolic velocity (\n                      <jats:styled-content style=\"fixed-case\">TASV<\/jats:styled-content>\n                      or S\u2032) (13.1 \u00b1 3.0 cm\/sec vs. 16.0 \u00b1 2.8 cm\/sec), E\/A (1.4 \u00b1 0.3 vs. 1.7 \u00b1 0.5), and E\/e\u2032 (5.9 \u00b1 5.0 vs. 7.2 \u00b1 2.0) in comparison with baseline. Six months after closure, there were statistically significant decreases in\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      major dimension (5.9 \u00b1 1.1 cm vs. 6.3 \u00b1 1.0 cm),\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>\n                      end\u2010diastolic diameter ratio (0.8 \u00b1 0.1 vs. 0.9 \u00b1 0.1),\n                      <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>\n                      major dimension (4.1 \u00b1 0.8 cm vs. 4.4 \u00b1 0.8 cm), and\n                      <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>\n                      end\u2010systolic area (11.4 \u00b1 3.8 cm\n                      <jats:sup>2<\/jats:sup>\n                      vs. 13.2 \u00b1 4.6 cm\n                      <jats:sup>2<\/jats:sup>\n                      ) in comparison with 1 month post\u2013device closure. After 6 months, there was a statistically insignificant increase in both\n                      <jats:styled-content style=\"fixed-case\">TASV<\/jats:styled-content>\n                      (13.7 \u00b1 2.8 cm\/sec vs. 13.1 \u00b1 3.0 cm\/sec) and\n                      <jats:styled-content style=\"fixed-case\">TAPSE<\/jats:styled-content>\n                      (2.5 \u00b1 1.6 cm\/sec vs. 2.2 \u00b1 1.8 cm\/sec). There was no significant change in tissue Doppler\n                      <jats:styled-content style=\"fixed-case\">MPI<\/jats:styled-content>\n                      at baseline, 1 month, and 6 months after closure (0.38 \u00b1 0.19 vs. 0.35 \u00b1 0.15 vs. 0.38 \u00b1 0.13). There was significant decrease in E\/e\u2032 from baseline to 1 month and 1 month to 6 months after closure (7.2 \u00b1 2.0 vs. 5.9 \u00b1 5.0 vs. 4.7 \u00b1 1.5).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      volumes decreased significantly in the first month after\n                      <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>\n                      device closure and continued up to 6 months. There was no change in global right ventricular systolic function but a high basal\n                      <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\n                      systolic function decreased after closure. Some patients had impaired diastolic function before closure of defect, which reversed to normal within 6 months after closure. Diastolic dysfunction in older age\u2010group may be a cause for long duration taken by right heart chambers to regress and deserves further investigation.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/echo.13250","type":"journal-article","created":{"date-parts":[[2016,4,24]],"date-time":"2016-04-24T23:48:39Z","timestamp":1461541719000},"page":"1381-1388","source":"Crossref","is-referenced-by-count":32,"title":["Right Ventricle before and after Atrial Septal Defect Device Closure"],"prefix":"10.1111","volume":"33","author":[{"given":"Vidya Sagar","family":"Akula","sequence":"first","affiliation":[{"name":"Department of Cardiology Sri Venkateswara Institute of Medical Sciences Tirupati Andhra Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajasekhar","family":"Durgaprasad","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sri Venkateswara Institute of Medical Sciences Tirupati Andhra Pradesh 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