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In preparation for the procedure, echocardiography is the method of choice for assessment of mitral valve (<jats:styled-content style=\"fixed-case\">MV<\/jats:styled-content>) morphology and function and thus provides important information if successful treatment of <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> can be accomplished by MitraClip. This review article provides structured and detailed guidance how to systematically assess functional and degenerative <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MV<\/jats:styled-content> pathology by echocardiography in order to select eligible patients for this procedure. 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