{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:16:40Z","timestamp":1761844600299},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008373","name":"Takeda Pharmaceutical Company Limited","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008373","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004820","name":"Mochida Pharmaceutical Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004820","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002973","name":"Daiichi-Sankyo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002973","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Our recent report demonstrated that atrial electromechanical conduction time (<jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5) measured with speckle tracking echocardiography could predict cardiac events in patients with pathological left ventricular hypertrophy. This study aimed to validate <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 by comparison with electroanatomical mapping and to investigate the clinical utility of <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 in patients with atrial fibrillation (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) undergoing catheter ablation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010six patients with preserved <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> ejection fraction (<jats:styled-content style=\"fixed-case\">LVEF<\/jats:styled-content> \u2265 50%) undergoing pulmonary vein isolation (<jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>) for <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> were studied. Atrial electrical conduction delay was determined by measuring atrial electrical activation time (<jats:styled-content style=\"fixed-case\">EAT<\/jats:styled-content>) using three\u2010dimensional electroanatomical mapping just after <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>. Echocardiographic parameters were acquired within 24 hours and at 6 months after <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>. The study also included 10 control subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> patients had a larger left atrial (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) volume index (<jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content>) and more prolonged <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 compared with control subjects. According to the validation study, <jats:styled-content style=\"fixed-case\">EAT<\/jats:styled-content> was closely related to <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 and a\u2032, and this association was independent of <jats:styled-content style=\"fixed-case\">LAVI<\/jats:styled-content> and the presence of persistent <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5: R<jats:sup>2<\/jats:sup> = 0.342, P &lt; 0.0001, a\u2032: R<jats:sup>2<\/jats:sup> = 0.337, P &lt; 0.0001). At 6 months after <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> LAVI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 were significantly improved. During continued follow\u2010up beyond 6 months (total follow\u2010up, 26 \u00b1 12 months), the <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 shortening at 6 months after <jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content> was significantly greater in <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\u2010free patients than patients with <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> recurrence. Conclusions: This study suggested that the <jats:styled-content style=\"fixed-case\">EMT<\/jats:styled-content>\u2010\u03b5 could be a useful echocardiographic marker of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> electromechanical abnormalities in patients with <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13259","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T18:03:03Z","timestamp":1462384983000},"page":"1317-1325","source":"Crossref","is-referenced-by-count":6,"title":["Clinical Utility of Atrial Electromechanical Conduction Time Measured with Speckle Tracking Echocardiography after Catheter Ablation in Patients with Atrial Fibrillation: A Validation Study with Electroanatomical Mapping"],"prefix":"10.1111","volume":"33","author":[{"given":"Akira","family":"Fujii","sequence":"first","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuji","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Nagai","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhisa","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruyoshi","family":"Uetani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun\u2010ichi","family":"Funada","sequence":"additional","affiliation":[{"name":"Department of Cardiology National Hospital Organization Ehime Medical Center Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Okura","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; Nephrology Ehime University Graduate School of Medicine Toon Ehime Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitsuo","family":"Higaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pulmonology, Hypertension &amp; 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