{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T02:54:34Z","timestamp":1790218474188,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,6,25]],"date-time":"2016-06-25T00:00:00Z","timestamp":1466812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,9]]},"abstract":"Objective<\/jats:title>Peripartum cardiomyopathy (PPCM<\/jats:styled-content>) is a rare cause of heart failure that develops in the last month of pregnancy or within 5\u00a0months of delivery. Longitudinal systolic strain has been shown to be impaired in HF<\/jats:styled-content> patients with both preserved and depressed EF<\/jats:styled-content>, but has not previously characterized in patients with PPCM<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>The purpose of our study was to investigate the prognosis and recovery in patients with PPCM<\/jats:styled-content> and use 2D strain imaging to characterize regional and global LV<\/jats:styled-content> strain in patients with PPCM<\/jats:styled-content>. Between 2009 and 2014, we identified 47 newly diagnosed patients with PPCM<\/jats:styled-content> and reduced EF<\/jats:styled-content> (rPPCM<\/jats:styled-content>), and 14 patients within the first 4\u00a0weeks postpartum who presented with signs and symptoms of HF<\/jats:styled-content>, and elevated BNP<\/jats:styled-content>\/pro\u2010NT<\/jats:styled-content>\u2010BNP<\/jats:styled-content>, but preserved LVEF<\/jats:styled-content> (pPPCM<\/jats:styled-content>). We compared the echocardiographic characteristics of the patients with rPPCM<\/jats:styled-content> and pPPCM<\/jats:styled-content> with 14 healthy controls.<\/jats:p><\/jats:sec>Results<\/jats:title>All\u2010cause mortality was 10.6% (5\/47) and rehospitalization for HF<\/jats:styled-content> rate was 31.9% (15\/47) at a median follow\u2010up of 12.5\u00a0months (range: 1\u201360\u00a0months) in the rPPCM<\/jats:styled-content> group. In 25.5% (12\/47) of patients with rPPCM<\/jats:styled-content>, there was no recovery or worsening of LVEF<\/jats:styled-content>, while complete and partial (more than 10% increase but less than 55%) recovery was seen in 57.4% (27\/47) and 17% (8\/47) of patients, respectively. Global and longitudinal strain (GLS<\/jats:styled-content>) values were not independent predictors of all\u2010cause mortality or the composite endpoint of all\u2010cause mortality, rehospitalization, or no LVEF<\/jats:styled-content> recovery in these patients. GLS<\/jats:styled-content> and segmental strain were significantly lower in the preserved EF<\/jats:styled-content> group compared with controls but higher compared with PPCM<\/jats:styled-content> with reduced EF.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Global and segmental longitudinal strain parameters were significantly reduced in PPCM<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13277","type":"journal-article","created":{"date-parts":[[2016,6,25]],"date-time":"2016-06-25T05:56:45Z","timestamp":1466834205000},"page":"1354-1360","source":"Crossref","is-referenced-by-count":39,"title":["Longitudinal systolic strain profiles and outcomes in peripartum cardiomyopathy"],"prefix":"10.1111","volume":"33","author":[{"given":"Alexandros","family":"Briasoulis","sequence":"first","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Mocanu","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Marinescu","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama","family":"Qaqi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan","family":"Palla","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tesfaye","family":"Telila","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Afonso","sequence":"additional","affiliation":[{"name":"Division of Cardiology Detroit Medical Center Wayne State University Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfq120"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.01.039"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000162478.36652.7E"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200004133421502"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00624-5"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.014"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.01.007"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.09.009"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-302760"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfs070"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.04.037"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-008-9414-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn141"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2011.01384.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-012-0256-z"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13277","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T18:39:19Z","timestamp":1694889559000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,25]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/echo.13277"],"URL":"https:\/\/doi.org\/10.1111\/echo.13277","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,25]]}}}