{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T21:17:51Z","timestamp":1770326271715,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,6,25]],"date-time":"2016-06-25T00:00:00Z","timestamp":1466812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,10]]},"abstract":"Aims<\/jats:title>Extent of left ventricular (LV<\/jats:styled-content>) reverse remodeling after aortic valve repair or replacement (AVR<\/jats:styled-content>) may differ between patients operated for acute aortic regurgitation (AR<\/jats:styled-content>) and chronic AR<\/jats:styled-content>. The aim of this study was to compare changes in LV<\/jats:styled-content> volumes and function between patients with acute and chronic AR<\/jats:styled-content> who underwent AVR<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods and Results<\/jats:title>A total of 98 patients (54\u00b115\u00a0years, 61% men) with acute (n=21) or chronic AR<\/jats:styled-content> (n=77) were included in the present retrospective evaluation. LV<\/jats:styled-content> volumes, LV<\/jats:styled-content> ejection fraction, and global longitudinal strain indexed for LV<\/jats:styled-content> end\u2010diastolic volume (GLS<\/jats:styled-content>i) were assessed preoperatively and after a median follow\u2010up of 28\u00a0months (interquartile range: 17\u201366\u00a0months). Patients with acute AR<\/jats:styled-content> tended to have smaller preoperative LV<\/jats:styled-content> end\u2010diastolic volume compared with chronic AR<\/jats:styled-content> (156\u00b115 vs 183\u00b16\u00a0mL; P<\/jats:italic>=.070). Both in patients with acute and chronic AR<\/jats:styled-content>, significant LV<\/jats:styled-content> reverse remodeling with sustained reduction in LV<\/jats:styled-content> volumes occurred during follow\u2010up with a significant smaller LV<\/jats:styled-content> end\u2010diastolic volume in acute AR<\/jats:styled-content> compared with chronic AR<\/jats:styled-content> (106\u00b18 vs 128\u00b15\u00a0mL; P<\/jats:italic>=.032). Preoperative and postoperative LV<\/jats:styled-content> ejection fractions were not significantly different between groups. In contrast, GLS<\/jats:styled-content>i was better in patients with acute AR<\/jats:styled-content> compared with chronic AR<\/jats:styled-content> before AVR<\/jats:styled-content> (\u22121.34\u00b10.20 vs \u22120.96\u00b10.07%\/10\u00a0mL; P<\/jats:italic>=.042) and during follow\u2010up (\u22121.65\u00b10.16 vs \u22121.29\u00b10.07%\/10\u00a0mL; P<\/jats:italic>=.017).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>After AVR<\/jats:styled-content>, LV<\/jats:styled-content> reverse remodeling occurs both in patients with acute and chronic AR<\/jats:styled-content>. However, LV<\/jats:styled-content> end\u2010diastolic volume was more reduced and GLS<\/jats:styled-content>i was more preserved during follow\u2010up in acute AR<\/jats:styled-content> than in chronic AR<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13295","type":"journal-article","created":{"date-parts":[[2016,6,26]],"date-time":"2016-06-26T07:53:06Z","timestamp":1466927586000},"page":"1458-1464","source":"Crossref","is-referenced-by-count":19,"title":["Left ventricular reverse remodeling after aortic valve surgery for acute versus chronic aortic regurgitation"],"prefix":"10.1111","volume":"33","author":[{"given":"Madelien V.","family":"Regeer","sequence":"first","affiliation":[{"name":"Heart Lung Center Leiden Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel I. 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M.","family":"Klautz","sequence":"additional","affiliation":[{"name":"Heart Lung Center Leiden Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen J.","family":"Bax","sequence":"additional","affiliation":[{"name":"Heart Lung Center Leiden Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Delgado","sequence":"additional","affiliation":[{"name":"Heart Lung Center Leiden Leiden University Medical Center Leiden The 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