{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T15:36:24Z","timestamp":1776872184970,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T00:00:00Z","timestamp":1471651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,10]]},"abstract":"Background<\/jats:title>Echocardiogram has limitations in effectively assessing right ventricular (RV<\/jats:styled-content>) function in children post tetralogy of Fallot (TOF<\/jats:styled-content>) repair. We evaluated the utility of speckle tracking echocardiography (STE<\/jats:styled-content>)\u2010based RV<\/jats:styled-content> global longitudinal strain (GLS<\/jats:styled-content>) for the assessment of RV<\/jats:styled-content> systolic function.<\/jats:p><\/jats:sec>Methods<\/jats:title>All patients with repaired TOF<\/jats:styled-content> who had both echocardiograms and cardiac MRI<\/jats:styled-content> (CMR<\/jats:styled-content>) within a 6\u2010month interval were included. RV<\/jats:styled-content> volumes and ejection fraction (EF<\/jats:styled-content>) were obtained by CMR<\/jats:styled-content>s. Traditional echocardiographic function parameters and RV GLS<\/jats:styled-content> were compared to CMR<\/jats:styled-content>\u2010derived RV EF<\/jats:styled-content>. Subjects were divided into two groups based on CMR RV EF<\/jats:styled-content> (group I: RV EF<\/jats:styled-content> \u226545%; and group II<\/jats:styled-content>: RV EF<\/jats:styled-content> <45%).<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 57 subjects were included. Mean age was 13.0\u00b13.6\u00a0years and 58% were males. Group I had 39 subjects and group II<\/jats:styled-content> had 18. Only six of the 18 patients (33%) in group II<\/jats:styled-content> were identified as having at least mild RV<\/jats:styled-content> dysfunction by echocardiogram. The mean RV GLS<\/jats:styled-content> was significantly abnormal in group II<\/jats:styled-content> (\u221215.3\u00b13.8%) compared to group I (\u221220.9\u00b13.3%; P<\/jats:italic><.001). By ROC<\/jats:styled-content> analysis, an RV GLS<\/jats:styled-content> cutoff value of \u221218% had 78% sensitivity and 77% specificity in identifying RV EF<\/jats:styled-content> <45% (area under curve .87, P<\/jats:italic><.001). Intra\u2010 and inter\u2010observer reproducibility of RV GLS<\/jats:styled-content> were good.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>RV GLS<\/jats:styled-content> is a simple and effective tool for the assessment of RV<\/jats:styled-content> systolic function in patients post TOF<\/jats:styled-content> repair. This technique would help further refine patient selection for timing of CMR<\/jats:styled-content> and management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13302","type":"journal-article","created":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T07:59:11Z","timestamp":1471679951000},"page":"1557-1562","source":"Crossref","is-referenced-by-count":23,"title":["Right ventricular global longitudinal strain in repaired tetralogy of Fallot"],"prefix":"10.1111","volume":"33","author":[{"given":"Kamill Del","family":"Toro","sequence":"first","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Seattle Children's Hospital Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian D.","family":"Soriano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Seattle Children's Hospital Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujatha","family":"Buddhe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Seattle Children's Hospital Seattle Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02938380"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.10.045"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-13-9"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2006.02.009"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80161-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12386"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.03.077"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-008-9314-4"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1316-0"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2007.00068.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.4.487"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-008-9387-0"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0213-z"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.11.009"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e32833bb524"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.040"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2002.116532"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-5-27"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.03.056"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.09.005"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jen315"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02435-9"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-010-0123-3"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-009-9477-7"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24610"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13302","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T12:47:22Z","timestamp":1695559642000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,20]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1111\/echo.13302"],"URL":"https:\/\/doi.org\/10.1111\/echo.13302","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,20]]}}}