{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:25:58Z","timestamp":1761017158869},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T00:00:00Z","timestamp":1476403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Adult studies demonstrate that echocardiographic measurements of cardiac function using speckle tracking correlate with invasive measurements, but such data in the pediatric population are sparse. Our aim was to compare speckle\u2010derived measures of cardiac function to measurements routinely obtained by cardiac catheterization in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Echocardiograms were performed on the day of cardiac catheterization. Using Tomtec 2D Cardiac Performance Analysis, longitudinal strain (<jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>), longitudinal strain rate (<jats:styled-content style=\"fixed-case\">LSR<\/jats:styled-content>), early diastolic <jats:styled-content style=\"fixed-case\">LSR<\/jats:styled-content>, and ejection fraction (<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>) for the right and left ventricle (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) were calculated via speckle tracking. Global <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LSR<\/jats:styled-content> were calculated for the <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>. These results were compared to cardiac index, maximum ventricular dp\/dt (max dp\/dt), ventricular end\u2010diastolic pressure (<jats:styled-content style=\"fixed-case\">EDP<\/jats:styled-content>), and pulmonary capillary wedge pressure (<jats:styled-content style=\"fixed-case\">PCWP<\/jats:styled-content>) obtained by fluid\u2010filled catheters. A blinded observer performed all echo measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty studies were performed on 28 patients ages 4\u00a0months to 20\u00a0years old. Their diagnoses included cardiac transplant (48 studies), repaired <jats:styled-content style=\"fixed-case\">AV<\/jats:styled-content> septal defect (1), and dilated cardiomyopathy (1). <jats:styled-content style=\"fixed-case\">RVEDP<\/jats:styled-content> ranged from 2 to 22\u00a0mm Hg (median=6) and <jats:styled-content style=\"fixed-case\">PCWP<\/jats:styled-content> ranged from 6 to 32\u00a0mmHg (median 10). <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> global <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> 2\u2010chamber <jats:styled-content style=\"fixed-case\">LSR<\/jats:styled-content> by speckle\u2010tracking negatively correlated with <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> max dp\/dt (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> global <jats:styled-content style=\"fixed-case\">LS <\/jats:styled-content><jats:italic>R<\/jats:italic>=\u2212.83, <jats:italic>P<\/jats:italic>=.001; <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> 2\u2010chamber <jats:styled-content style=\"fixed-case\">LSR <\/jats:styled-content><jats:italic>R<\/jats:italic>=\u2212.69, <jats:italic>P<\/jats:italic>=.009). <jats:styled-content style=\"fixed-case\">RV LS<\/jats:styled-content> weakly correlated with max dp\/dt (<jats:italic>R<\/jats:italic>=.363, <jats:italic>P<\/jats:italic>=.002). Early diastolic strain rate did not correlate with <jats:styled-content style=\"fixed-case\">EDP<\/jats:styled-content> in either ventricle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Speckle\u2010derived measurements of function in the <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> have stronger correlation than the <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content> to catheter\u2010derived measures. <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> global <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content> has the strongest correlation with invasive function measures in children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13347","type":"journal-article","created":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T06:53:16Z","timestamp":1476427996000},"page":"1903-1910","source":"Crossref","is-referenced-by-count":5,"title":["Interpreting measurements of cardiac function using vendor\u2010independent speckle tracking echocardiography in children: a prospective, blinded comparison with catheter\u2010derived measurements"],"prefix":"10.1111","volume":"33","author":[{"given":"Suma P.","family":"Goudar","sequence":"first","affiliation":[{"name":"Ward Family Heart Center Children's Mercy Hospital  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Hamilton","family":"Baker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Medical University of South Carolina  Charleston South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahryar M.","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Medical University of South Carolina  Charleston South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly J.","family":"Reid","sequence":"additional","affiliation":[{"name":"Ward Family Heart Center Children's Mercy Hospital  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish","family":"Shirali","sequence":"additional","affiliation":[{"name":"Ward Family Heart Center Children's Mercy Hospital  Kansas City Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Scheurer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Pediatric Cardiology Medical University of South Carolina  Charleston South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.11.034"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.040"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000019907.77526.75"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.08.010"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-009-9477-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jeq088"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.09.008"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.11.039"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.09.018"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.08.011"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.01.021"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.01.015"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.114.002110"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/AC.69.3.3027831"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.08.002"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0102.101396"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.08.007"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.662882"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.02.017"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13347","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13347","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:40:22Z","timestamp":1695552022000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,14]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/echo.13347"],"URL":"https:\/\/doi.org\/10.1111\/echo.13347","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,14]]}}}