{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T06:45:35Z","timestamp":1695624335387},"reference-count":10,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T00:00:00Z","timestamp":1472169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Mitral valve resistance (<jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content>) is a hemodynamic consequence of mitral stenosis (<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>), but it has no clear threshold with a shortage of data to be reliable. We aimed to investigate match and mismatch between opening area and resistance especially in patients with moderate and mild <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study comprised 88 patients with moderate and mild rheumatic <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>. Transthoracic echocardiographic study estimated the following: mitral valve area (<jats:styled-content style=\"fixed-case\">MVA<\/jats:styled-content>) by both planimetry (2D) and pressure half\u2010time (<jats:styled-content style=\"fixed-case\">PHT<\/jats:styled-content>), mitral valve score (<jats:styled-content style=\"fixed-case\">MVS<\/jats:styled-content>), mean transmitral pressure gradient (<jats:styled-content style=\"fixed-case\">MPG<\/jats:styled-content>), diastolic filling time (<jats:styled-content style=\"fixed-case\">DFT<\/jats:styled-content>), left ventricular out flow tract diameter (<jats:styled-content style=\"fixed-case\">LVOT<\/jats:styled-content>d) and velocity\u2010time integral (<jats:styled-content style=\"fixed-case\">LVOT<\/jats:styled-content>vti), and <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> = <jats:styled-content style=\"fixed-case\">MPG<\/jats:styled-content>\/aortic flow ratio [(<jats:styled-content style=\"fixed-case\">LVOT<\/jats:styled-content>d) (<jats:styled-content style=\"fixed-case\">LVOT<\/jats:styled-content>vti)\/<jats:styled-content style=\"fixed-case\">DFT<\/jats:styled-content>] in dynes\u00b7s\/cm<jats:sup>5<\/jats:sup>. Patients were classified into two groups: group 1 (51 patients) with matched <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> and group 2 (37 patients) with mismatched higher <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the matched group, moderate <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> showed <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> &lt;105 dynes\u00b7s\/cm<jats:sup>5<\/jats:sup> and &lt;76dynes\u00b7s\/cm<jats:sup>5<\/jats:sup> with mild <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>. Group 2 compared to group 1 had higher <jats:styled-content style=\"fixed-case\">NYHA<\/jats:styled-content> class (1.4\u00b10.6 vs 1.2\u00b10.4, <jats:italic>P<\/jats:italic>&lt;.05) and higher <jats:styled-content style=\"fixed-case\">MVS<\/jats:styled-content> (8.1\u00b11.8 vs 7\u00b10.9, <jats:italic>P<\/jats:italic>&lt;.05). <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> showed positive correlation with <jats:styled-content style=\"fixed-case\">MVS<\/jats:styled-content> (r=.5, <jats:italic>P<\/jats:italic>&lt;.05), and logistic regression analysis showed that <jats:styled-content style=\"fixed-case\">MVS<\/jats:styled-content> is the only independent predictor of the <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> severity in the mismatched group (i.e., with higher <jats:styled-content style=\"fixed-case\">MVR<\/jats:styled-content> compared to the <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content> analysis results) (B\u00b1<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>=6.997\u00b12.826, t=2.476, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.241\u00b112.752 with an odds ratio=0.412, <jats:italic>P<\/jats:italic>&lt;.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>On investigating match and mismatch between opening area and resistance, the only independent predictor of mismatch is the mitral valve score.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13349","type":"journal-article","created":{"date-parts":[[2016,8,27]],"date-time":"2016-08-27T04:50:02Z","timestamp":1472273402000},"page":"1801-1804","source":"Crossref","is-referenced-by-count":0,"title":["Match and mismatch between opening area and resistance in mild and moderate rheumatic mitral stenosis"],"prefix":"10.1111","volume":"33","author":[{"given":"Ibtesam Ibrahim","family":"El\u2010Dosouky","sequence":"first","affiliation":[{"name":"Cardiology Department Faculty of Medicine Zagazig University  Zagazig Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00326-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2007.02.006"},{"key":"e_1_2_7_4_1","first-page":"455","article-title":"Clinico\u2010morphological dissociation in patients with mitral valve stenosis","volume":"64","author":"Rossi EG","year":"1995","journal-title":"Arg Bras Cardiol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.60.4.299"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_7_7_1","first-page":"1553","volume-title":"Braunwald's Heart Disease: A Textbook of Cardiovascular Disease","author":"Bonow R","year":"2004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.2.893"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90445-S"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90679-U"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90504-R"}],"container-title":["Echocardiography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13349","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fecho.13349","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/echo.13349","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:39:52Z","timestamp":1695551992000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/echo.13349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,26]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/echo.13349"],"URL":"https:\/\/doi.org\/10.1111\/echo.13349","archive":["Portico"],"relation":{},"ISSN":["0742-2822","1540-8175"],"issn-type":[{"value":"0742-2822","type":"print"},{"value":"1540-8175","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,26]]}}}