{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:17:40Z","timestamp":1790698660840,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T00:00:00Z","timestamp":1483401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Echocardiography"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study focuses on determining concomitant persistent left superior vena cava (<jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content>) in patients with congenital heart disease (<jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2005 and 2012, a total of 2.663 patients with <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>, 88 (3.3%) of whom were diagnosed with persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content>, were evaluated retrospectively. The demographic characteristics of patients, clinical and radiographic findings, echocardiography, cardiac catheterization, and angiography results obtained from the patients\u2019 records were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of the patients was 9.5\u00a0months, and 46 of the 88 (52.3%) patients were female. The most common concomitant <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> were ventricular septal defect, double outlet right ventricle (<jats:styled-content style=\"fixed-case\">DORV<\/jats:styled-content>), and tetralogy of Fallot (<jats:styled-content style=\"fixed-case\">TOF<\/jats:styled-content>). When the patients were compared according to their <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content>, persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> frequency was significantly higher in those with <jats:styled-content style=\"fixed-case\">DORV<\/jats:styled-content> (<jats:italic>P<\/jats:italic>&lt;.001), <jats:styled-content style=\"fixed-case\">TOF<\/jats:styled-content> (<jats:italic>P<\/jats:italic>=.04), patent ductus arteriosus (<jats:italic>P<\/jats:italic>=.01), and atrial septal defect (<jats:italic>P<\/jats:italic>=.03). Eighty\u2010three of the 88 (94.3%) patients with persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> had right <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content>, and 5 (5.7%) had absence of the right <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content>. Twenty\u2010seven of the 83 (32.5%) patients with double <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> had connected normal innominate vein. In all cases, right aortic arch association was seen in 14 (15.9%) patients. Eighty\u2010four (95.4%) of the patients were diagnosed by echocardiography prior to catheter angiography. Persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> drained to the coronary sinus in all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Increased awareness about the association of certain <jats:styled-content style=\"fixed-case\">CHD<\/jats:styled-content> with persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> and a careful echocardiographic examination can facilitate the diagnosis of persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content>. In addition, precise prior diagnosis of persistent left <jats:styled-content style=\"fixed-case\">SVC<\/jats:styled-content> can prevent complications during surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/echo.13447","type":"journal-article","created":{"date-parts":[[2017,1,4]],"date-time":"2017-01-04T04:42:42Z","timestamp":1483504962000},"page":"436-440","source":"Crossref","is-referenced-by-count":27,"title":["Persistent left superior vena cava accompanying congenital heart disease in children: Experience of a tertiary care center"],"prefix":"10.1111","volume":"34","author":[{"given":"Mehmet Emre","family":"Ari","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology Dr. Sami Ulus Obstetrics and Gynecology Children's Health and Diseases Training and Research Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vehbi","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Dr. 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